| Full name: testis specific serine kinase 3 | Alias Symbol: SPOGA3 | ||
| Type: protein-coding gene | Cytoband: 1p35.1 | ||
| Entrez ID: 81629 | HGNC ID: HGNC:15473 | Ensembl Gene: ENSG00000162526 | OMIM ID: 607660 |
| Drug and gene relationship at DGIdb | |||
Expression of TSSK3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSSK3 | 81629 | 1552395_at | 0.0135 | 0.9700 | |
| GSE26886 | TSSK3 | 81629 | 1552395_at | -0.0905 | 0.5814 | |
| GSE45670 | TSSK3 | 81629 | 1552395_at | 0.1258 | 0.1155 | |
| GSE53622 | TSSK3 | 81629 | 5533 | 0.0797 | 0.2422 | |
| GSE53624 | TSSK3 | 81629 | 5533 | -0.2966 | 0.0000 | |
| GSE63941 | TSSK3 | 81629 | 1552395_at | 0.2519 | 0.1098 | |
| GSE77861 | TSSK3 | 81629 | 1552395_at | -0.0141 | 0.9015 | |
| GSE97050 | TSSK3 | 81629 | A_23_P399681 | -0.2377 | 0.3156 | |
| SRP064894 | TSSK3 | 81629 | RNAseq | 0.4680 | 0.0745 | |
| SRP133303 | TSSK3 | 81629 | RNAseq | -0.2867 | 0.1220 | |
| SRP159526 | TSSK3 | 81629 | RNAseq | 0.3384 | 0.5719 | |
| SRP193095 | TSSK3 | 81629 | RNAseq | 0.3452 | 0.0512 | |
| SRP219564 | TSSK3 | 81629 | RNAseq | -0.4217 | 0.3026 | |
| TCGA | TSSK3 | 81629 | RNAseq | -0.0753 | 0.6680 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TSSK3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSSK3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSSK3 | 81629 | 1 | 5 | 24 | |
| GSE20123 | TSSK3 | 81629 | 1 | 4 | 25 | |
| GSE43470 | TSSK3 | 81629 | 6 | 4 | 33 | |
| GSE46452 | TSSK3 | 81629 | 5 | 1 | 53 | |
| GSE47630 | TSSK3 | 81629 | 8 | 3 | 29 | |
| GSE54993 | TSSK3 | 81629 | 1 | 1 | 68 | |
| GSE54994 | TSSK3 | 81629 | 11 | 2 | 40 | |
| GSE60625 | TSSK3 | 81629 | 0 | 0 | 11 | |
| GSE74703 | TSSK3 | 81629 | 3 | 3 | 30 | |
| GSE74704 | TSSK3 | 81629 | 0 | 0 | 20 | |
| TCGA | TSSK3 | 81629 | 11 | 19 | 66 |
Total number of gains: 47; Total number of losses: 42; Total Number of normals: 399.
Somatic mutations of TSSK3:
Generating mutation plots.
Highly correlated genes for TSSK3:
Showing top 20/400 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSSK3 | INSC | 0.846749 | 3 | 0 | 3 |
| TSSK3 | OR2B11 | 0.845742 | 3 | 0 | 3 |
| TSSK3 | TERT | 0.842901 | 3 | 0 | 3 |
| TSSK3 | PAX6 | 0.840529 | 3 | 0 | 3 |
| TSSK3 | SLC22A12 | 0.835208 | 4 | 0 | 4 |
| TSSK3 | YY2 | 0.829265 | 3 | 0 | 3 |
| TSSK3 | PRSS38 | 0.826127 | 3 | 0 | 3 |
| TSSK3 | ESPNL | 0.821509 | 4 | 0 | 4 |
| TSSK3 | PRG3 | 0.811862 | 3 | 0 | 3 |
| TSSK3 | PDE6C | 0.810795 | 3 | 0 | 3 |
| TSSK3 | KCNC3 | 0.808194 | 3 | 0 | 3 |
| TSSK3 | ST8SIA1 | 0.804126 | 3 | 0 | 3 |
| TSSK3 | ATP2B3 | 0.803707 | 3 | 0 | 3 |
| TSSK3 | OTOG | 0.799724 | 3 | 0 | 3 |
| TSSK3 | BSX | 0.793011 | 3 | 0 | 3 |
| TSSK3 | CLEC4D | 0.791519 | 3 | 0 | 3 |
| TSSK3 | ANO7 | 0.782145 | 4 | 0 | 4 |
| TSSK3 | OSM | 0.779665 | 3 | 0 | 3 |
| TSSK3 | SLC6A13 | 0.774887 | 4 | 0 | 4 |
| TSSK3 | KRT77 | 0.773076 | 3 | 0 | 3 |
For details and further investigation, click here
