| Full name: olfactory receptor family 2 subfamily B member 11 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 127623 | HGNC ID: HGNC:31249 | Ensembl Gene: ENSG00000177535 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
OR2B11 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR2B11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | OR2B11 | 127623 | 24724 | 0.0571 | 0.5179 | |
| GSE53624 | OR2B11 | 127623 | 24724 | -0.0112 | 0.9087 | |
| GSE97050 | OR2B11 | 127623 | A_33_P3310377 | -0.2170 | 0.4023 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR2B11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR2B11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR2B11 | 127623 | 7 | 1 | 22 | |
| GSE20123 | OR2B11 | 127623 | 7 | 1 | 22 | |
| GSE43470 | OR2B11 | 127623 | 4 | 3 | 36 | |
| GSE46452 | OR2B11 | 127623 | 4 | 2 | 53 | |
| GSE47630 | OR2B11 | 127623 | 15 | 1 | 24 | |
| GSE54993 | OR2B11 | 127623 | 0 | 6 | 64 | |
| GSE54994 | OR2B11 | 127623 | 18 | 0 | 35 | |
| GSE60625 | OR2B11 | 127623 | 0 | 0 | 11 | |
| GSE74703 | OR2B11 | 127623 | 4 | 1 | 31 | |
| GSE74704 | OR2B11 | 127623 | 2 | 0 | 18 | |
| TCGA | OR2B11 | 127623 | 45 | 4 | 47 |
Total number of gains: 106; Total number of losses: 19; Total Number of normals: 363.
Somatic mutations of OR2B11:
Generating mutation plots.
Highly correlated genes for OR2B11:
Showing top 20/178 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR2B11 | OR1F1 | 0.889571 | 3 | 0 | 3 |
| OR2B11 | PRSS38 | 0.858573 | 3 | 0 | 3 |
| OR2B11 | TSSK3 | 0.845742 | 3 | 0 | 3 |
| OR2B11 | TTLL9 | 0.838412 | 3 | 0 | 3 |
| OR2B11 | YY2 | 0.837162 | 3 | 0 | 3 |
| OR2B11 | OR2T4 | 0.833587 | 3 | 0 | 3 |
| OR2B11 | RBM43 | 0.833561 | 3 | 0 | 3 |
| OR2B11 | FFAR1 | 0.828882 | 3 | 0 | 3 |
| OR2B11 | KCNQ4 | 0.828216 | 3 | 0 | 3 |
| OR2B11 | PAX6 | 0.827112 | 3 | 0 | 3 |
| OR2B11 | AANAT | 0.825091 | 3 | 0 | 3 |
| OR2B11 | PROCA1 | 0.815156 | 3 | 0 | 3 |
| OR2B11 | INSC | 0.813498 | 3 | 0 | 3 |
| OR2B11 | OR2D2 | 0.813051 | 3 | 0 | 3 |
| OR2B11 | TFE3 | 0.812768 | 3 | 0 | 3 |
| OR2B11 | KCNC3 | 0.811846 | 3 | 0 | 3 |
| OR2B11 | DYTN | 0.808178 | 3 | 0 | 3 |
| OR2B11 | OR4D1 | 0.807651 | 3 | 0 | 3 |
| OR2B11 | AQP8 | 0.805051 | 3 | 0 | 3 |
| OR2B11 | SLC22A12 | 0.804359 | 3 | 0 | 3 |
For details and further investigation, click here
