| Full name: glycoprotein hormone subunit beta 5 | Alias Symbol: ZLUT1|GPB5 | ||
| Type: protein-coding gene | Cytoband: 14q23.2 | ||
| Entrez ID: 122876 | HGNC ID: HGNC:18055 | Ensembl Gene: ENSG00000179600 | OMIM ID: 609652 |
| Drug and gene relationship at DGIdb | |||
Expression of GPHB5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPHB5 | 122876 | 1553945_at | 0.0667 | 0.8672 | |
| GSE26886 | GPHB5 | 122876 | 1553945_at | -0.0175 | 0.9202 | |
| GSE45670 | GPHB5 | 122876 | 1553945_at | 0.2389 | 0.0080 | |
| GSE53622 | GPHB5 | 122876 | 98228 | -0.2727 | 0.0193 | |
| GSE53624 | GPHB5 | 122876 | 98228 | -0.7319 | 0.0000 | |
| GSE63941 | GPHB5 | 122876 | 1553945_at | 0.0579 | 0.7170 | |
| GSE77861 | GPHB5 | 122876 | 1553945_at | -0.0612 | 0.5199 | |
| GSE97050 | GPHB5 | 122876 | A_23_P336678 | 0.0592 | 0.8403 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GPHB5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPHB5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPHB5 | 122876 | 7 | 3 | 20 | |
| GSE20123 | GPHB5 | 122876 | 7 | 3 | 20 | |
| GSE43470 | GPHB5 | 122876 | 8 | 2 | 33 | |
| GSE46452 | GPHB5 | 122876 | 16 | 3 | 40 | |
| GSE47630 | GPHB5 | 122876 | 11 | 9 | 20 | |
| GSE54993 | GPHB5 | 122876 | 3 | 9 | 58 | |
| GSE54994 | GPHB5 | 122876 | 18 | 5 | 30 | |
| GSE60625 | GPHB5 | 122876 | 0 | 2 | 9 | |
| GSE74703 | GPHB5 | 122876 | 7 | 2 | 27 | |
| GSE74704 | GPHB5 | 122876 | 3 | 2 | 15 | |
| TCGA | GPHB5 | 122876 | 32 | 14 | 50 |
Total number of gains: 112; Total number of losses: 54; Total Number of normals: 322.
Somatic mutations of GPHB5:
Generating mutation plots.
Highly correlated genes for GPHB5:
Showing top 20/267 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPHB5 | TSHB | 0.841739 | 3 | 0 | 3 |
| GPHB5 | KRTAP5-5 | 0.824698 | 3 | 0 | 3 |
| GPHB5 | KRTAP10-8 | 0.817456 | 3 | 0 | 3 |
| GPHB5 | RNF222 | 0.809551 | 3 | 0 | 3 |
| GPHB5 | CLEC18C | 0.802536 | 3 | 0 | 3 |
| GPHB5 | KRTAP5-4 | 0.799871 | 3 | 0 | 3 |
| GPHB5 | MGAT5B | 0.778792 | 4 | 0 | 4 |
| GPHB5 | KLK2 | 0.774559 | 4 | 0 | 4 |
| GPHB5 | SLC35F3 | 0.76941 | 3 | 0 | 3 |
| GPHB5 | KRTAP5-11 | 0.766973 | 3 | 0 | 3 |
| GPHB5 | DPYSL4 | 0.762858 | 3 | 0 | 3 |
| GPHB5 | BARHL2 | 0.762693 | 3 | 0 | 3 |
| GPHB5 | NOTO | 0.760538 | 3 | 0 | 3 |
| GPHB5 | TULP1 | 0.754228 | 3 | 0 | 3 |
| GPHB5 | PATE3 | 0.751859 | 3 | 0 | 3 |
| GPHB5 | SLC6A3 | 0.74574 | 3 | 0 | 3 |
| GPHB5 | GPR62 | 0.729189 | 5 | 0 | 3 |
| GPHB5 | KRT3 | 0.721091 | 4 | 0 | 4 |
| GPHB5 | SLC5A5 | 0.719816 | 4 | 0 | 3 |
| GPHB5 | CCL25 | 0.719297 | 3 | 0 | 3 |
For details and further investigation, click here
