| Full name: KIAA1109 | Alias Symbol: FLJ21404|FSA|KIAA1371|Tweek | ||
| Type: protein-coding gene | Cytoband: 4q27 | ||
| Entrez ID: 84162 | HGNC ID: HGNC:26953 | Ensembl Gene: ENSG00000138688 | OMIM ID: 611565 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of KIAA1109:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIAA1109 | 84162 | 212779_at | -0.1860 | 0.5682 | |
| GSE20347 | KIAA1109 | 84162 | 212779_at | -0.6242 | 0.0000 | |
| GSE23400 | KIAA1109 | 84162 | 212779_at | -0.2719 | 0.0068 | |
| GSE26886 | KIAA1109 | 84162 | 212779_at | 0.2398 | 0.4640 | |
| GSE29001 | KIAA1109 | 84162 | 212779_at | -0.4404 | 0.0867 | |
| GSE38129 | KIAA1109 | 84162 | 212779_at | -0.6956 | 0.0000 | |
| GSE45670 | KIAA1109 | 84162 | 212779_at | -0.5311 | 0.0005 | |
| GSE53622 | KIAA1109 | 84162 | 70213 | -0.3715 | 0.0000 | |
| GSE53624 | KIAA1109 | 84162 | 70213 | -0.5322 | 0.0000 | |
| GSE63941 | KIAA1109 | 84162 | 212779_at | -1.8830 | 0.0003 | |
| GSE77861 | KIAA1109 | 84162 | 212779_at | -0.3645 | 0.1418 | |
| GSE97050 | KIAA1109 | 84162 | A_24_P325176 | -0.3243 | 0.2152 | |
| SRP007169 | KIAA1109 | 84162 | RNAseq | 0.1600 | 0.6676 | |
| SRP008496 | KIAA1109 | 84162 | RNAseq | 0.2196 | 0.3198 | |
| SRP064894 | KIAA1109 | 84162 | RNAseq | -0.4891 | 0.0863 | |
| SRP133303 | KIAA1109 | 84162 | RNAseq | -0.0322 | 0.8864 | |
| SRP159526 | KIAA1109 | 84162 | RNAseq | -0.7498 | 0.0001 | |
| SRP193095 | KIAA1109 | 84162 | RNAseq | -0.2821 | 0.0057 | |
| SRP219564 | KIAA1109 | 84162 | RNAseq | -0.4878 | 0.1850 | |
| TCGA | KIAA1109 | 84162 | RNAseq | -0.2874 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KIAA1109 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIAA1109:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIAA1109 | 84162 | 1 | 13 | 16 | |
| GSE20123 | KIAA1109 | 84162 | 1 | 13 | 16 | |
| GSE43470 | KIAA1109 | 84162 | 0 | 13 | 30 | |
| GSE46452 | KIAA1109 | 84162 | 1 | 36 | 22 | |
| GSE47630 | KIAA1109 | 84162 | 0 | 22 | 18 | |
| GSE54993 | KIAA1109 | 84162 | 9 | 0 | 61 | |
| GSE54994 | KIAA1109 | 84162 | 1 | 10 | 42 | |
| GSE60625 | KIAA1109 | 84162 | 0 | 1 | 10 | |
| GSE74703 | KIAA1109 | 84162 | 0 | 11 | 25 | |
| GSE74704 | KIAA1109 | 84162 | 0 | 7 | 13 | |
| TCGA | KIAA1109 | 84162 | 8 | 36 | 52 |
Total number of gains: 21; Total number of losses: 162; Total Number of normals: 305.
Somatic mutations of KIAA1109:
Generating mutation plots.
Highly correlated genes for KIAA1109:
Showing top 20/1199 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIAA1109 | DPY19L3 | 0.730306 | 3 | 0 | 3 |
| KIAA1109 | RBM20 | 0.723278 | 4 | 0 | 4 |
| KIAA1109 | THAP8 | 0.719874 | 3 | 0 | 3 |
| KIAA1109 | SPATA9 | 0.711645 | 3 | 0 | 3 |
| KIAA1109 | BDH2 | 0.707439 | 10 | 0 | 10 |
| KIAA1109 | C11orf96 | 0.704119 | 3 | 0 | 3 |
| KIAA1109 | NLGN4Y | 0.703166 | 3 | 0 | 3 |
| KIAA1109 | NOA1 | 0.701761 | 3 | 0 | 3 |
| KIAA1109 | AFF1 | 0.701365 | 11 | 0 | 10 |
| KIAA1109 | ZNF776 | 0.699286 | 5 | 0 | 5 |
| KIAA1109 | ZNF626 | 0.697982 | 4 | 0 | 4 |
| KIAA1109 | KLHDC8B | 0.696014 | 3 | 0 | 3 |
| KIAA1109 | ZMAT1 | 0.69425 | 5 | 0 | 4 |
| KIAA1109 | PEX11B | 0.693508 | 3 | 0 | 3 |
| KIAA1109 | PPM1K | 0.690273 | 6 | 0 | 5 |
| KIAA1109 | PTAR1 | 0.688597 | 6 | 0 | 5 |
| KIAA1109 | DNAJC13 | 0.688335 | 4 | 0 | 3 |
| KIAA1109 | RHOJ | 0.687857 | 3 | 0 | 3 |
| KIAA1109 | DALRD3 | 0.687716 | 3 | 0 | 3 |
| KIAA1109 | USP9Y | 0.686876 | 4 | 0 | 4 |
For details and further investigation, click here
