RBM20

 

Full name: RNA binding motif protein 20 Alias Symbol: 
Type: protein-coding gene Cytoband: 10q25.2
Entrez ID: 282996 HGNC ID: HGNC:27424 Ensembl Gene: ENSG00000203867 OMIM ID: 613171
Drug and gene relationship at DGIdb

 

Expression of RBM20:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RBM20 282996 238763_at -1.6057 0.2970
GSE26886 RBM20 282996 238763_at -3.3441 0.0000
GSE45670 RBM20 282996 238763_at -2.6086 0.0000
GSE53622 RBM20 282996 24954 0.0882 0.4854
GSE53624 RBM20 282996 24954 0.0691 0.4967
GSE63941 RBM20 282996 238763_at 0.2305 0.6522
GSE77861 RBM20 282996 238763_at -0.9318 0.0189
GSE97050 RBM20 282996 A_33_P3307163 0.3831 0.2874
SRP007169 RBM20 282996 RNAseq -5.1122 0.0000
SRP064894 RBM20 282996 RNAseq -3.5720 0.0000
SRP133303 RBM20 282996 RNAseq -2.6274 0.0000
SRP159526 RBM20 282996 RNAseq -3.2912 0.0000
SRP193095 RBM20 282996 RNAseq -2.0848 0.0000
SRP219564 RBM20 282996 RNAseq -0.9602 0.4200
TCGA RBM20 282996 RNAseq -0.9563 0.0052

Upregulated datasets: 0; Downregulated datasets: 7.  


 

Survival by RBM20 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RBM20:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RBM20 282996 1 9 20
GSE20123 RBM20 282996 1 8 21
GSE43470 RBM20 282996 0 7 36
GSE46452 RBM20 282996 0 11 48
GSE47630 RBM20 282996 2 14 24
GSE54993 RBM20 282996 8 0 62
GSE54994 RBM20 282996 1 10 42
GSE60625 RBM20 282996 0 0 11
GSE74703 RBM20 282996 0 5 31
GSE74704 RBM20 282996 1 4 15
TCGA RBM20 282996 4 29 63

Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.  


 

Somatic mutations of RBM20:

 

Generating mutation plots.

 

Highly correlated genes for RBM20:

 

Showing top 20/1015 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RBM20MTMR100.841223404
RBM20PDLIM50.83279404
RBM20CD2AP0.827577303
RBM20MGST20.82469404
RBM20ELMO20.819444404
RBM20PAIP2B0.817436404
RBM20TRIM60.812834303
RBM20PRKAB10.809515404
RBM20CCDC60.804029404
RBM20CHIC20.802633303
RBM20CNN30.802014303
RBM20DOCK90.800421404
RBM20WDR260.799371404
RBM20PDZD80.797708303
RBM20CUL30.796865404
RBM20VSIG20.79585303
RBM20GDPD30.794355303
RBM20STK390.79152505
RBM20TJP10.790647404
RBM20CHMP2B0.789072404

For details and further investigation, click here