| Full name: THAP domain containing 8 | Alias Symbol: FLJ32891 | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 199745 | HGNC ID: HGNC:23191 | Ensembl Gene: ENSG00000161277 | OMIM ID: 612536 |
| Drug and gene relationship at DGIdb | |||
Expression of THAP8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THAP8 | 199745 | 228500_at | -0.2239 | 0.3805 | |
| GSE26886 | THAP8 | 199745 | 228500_at | 0.2396 | 0.2025 | |
| GSE45670 | THAP8 | 199745 | 228500_at | 0.1974 | 0.1736 | |
| GSE53622 | THAP8 | 199745 | 44660 | -0.1472 | 0.1784 | |
| GSE53624 | THAP8 | 199745 | 44660 | 0.1336 | 0.0380 | |
| GSE63941 | THAP8 | 199745 | 228500_at | -0.5985 | 0.0921 | |
| GSE77861 | THAP8 | 199745 | 228500_at | 0.0205 | 0.9422 | |
| GSE97050 | THAP8 | 199745 | A_24_P296907 | -0.1234 | 0.6519 | |
| SRP007169 | THAP8 | 199745 | RNAseq | 0.5457 | 0.4360 | |
| SRP064894 | THAP8 | 199745 | RNAseq | 0.9644 | 0.0038 | |
| SRP133303 | THAP8 | 199745 | RNAseq | -0.0782 | 0.7220 | |
| SRP159526 | THAP8 | 199745 | RNAseq | 0.0588 | 0.8626 | |
| SRP219564 | THAP8 | 199745 | RNAseq | -0.5360 | 0.3101 | |
| TCGA | THAP8 | 199745 | RNAseq | 0.1553 | 0.1158 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by THAP8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THAP8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THAP8 | 199745 | 7 | 4 | 19 | |
| GSE20123 | THAP8 | 199745 | 7 | 3 | 20 | |
| GSE43470 | THAP8 | 199745 | 3 | 7 | 33 | |
| GSE46452 | THAP8 | 199745 | 48 | 1 | 10 | |
| GSE47630 | THAP8 | 199745 | 9 | 5 | 26 | |
| GSE54993 | THAP8 | 199745 | 17 | 3 | 50 | |
| GSE54994 | THAP8 | 199745 | 6 | 9 | 38 | |
| GSE60625 | THAP8 | 199745 | 9 | 0 | 2 | |
| GSE74703 | THAP8 | 199745 | 3 | 4 | 29 | |
| GSE74704 | THAP8 | 199745 | 6 | 1 | 13 | |
| TCGA | THAP8 | 199745 | 22 | 10 | 64 |
Total number of gains: 137; Total number of losses: 47; Total Number of normals: 304.
Somatic mutations of THAP8:
Generating mutation plots.
Highly correlated genes for THAP8:
Showing top 20/262 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THAP8 | ITIH5 | 0.780542 | 3 | 0 | 3 |
| THAP8 | RNASE4 | 0.759254 | 3 | 0 | 3 |
| THAP8 | MYADM | 0.757454 | 3 | 0 | 3 |
| THAP8 | ZNF548 | 0.757126 | 3 | 0 | 3 |
| THAP8 | ANK2 | 0.751744 | 3 | 0 | 3 |
| THAP8 | PANK4 | 0.747786 | 3 | 0 | 3 |
| THAP8 | FBN1 | 0.739842 | 3 | 0 | 3 |
| THAP8 | PHF13 | 0.736449 | 3 | 0 | 3 |
| THAP8 | AKAP12 | 0.732548 | 3 | 0 | 3 |
| THAP8 | RRAGA | 0.731452 | 3 | 0 | 3 |
| THAP8 | FGFR1 | 0.730792 | 4 | 0 | 4 |
| THAP8 | OMD | 0.728315 | 3 | 0 | 3 |
| THAP8 | DIAPH2 | 0.725636 | 3 | 0 | 3 |
| THAP8 | CNTLN | 0.724081 | 3 | 0 | 3 |
| THAP8 | KIAA1109 | 0.719874 | 3 | 0 | 3 |
| THAP8 | VCP | 0.719305 | 3 | 0 | 3 |
| THAP8 | KCNK2 | 0.715099 | 3 | 0 | 3 |
| THAP8 | OLFML1 | 0.714615 | 4 | 0 | 3 |
| THAP8 | DAPK1 | 0.713793 | 3 | 0 | 3 |
| THAP8 | KCNA2 | 0.713734 | 4 | 0 | 3 |
For details and further investigation, click here
