| Full name: 3-hydroxybutyrate dehydrogenase 2 | Alias Symbol: UCPA-OR|FLJ13261|UNQ6308|PRO20933|SDR15C1 | ||
| Type: protein-coding gene | Cytoband: 4q24 | ||
| Entrez ID: 56898 | HGNC ID: HGNC:32389 | Ensembl Gene: ENSG00000164039 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of BDH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BDH2 | 56898 | 218285_s_at | -0.3985 | 0.3694 | |
| GSE20347 | BDH2 | 56898 | 218285_s_at | -0.4049 | 0.0366 | |
| GSE23400 | BDH2 | 56898 | 218285_s_at | -0.3204 | 0.0007 | |
| GSE26886 | BDH2 | 56898 | 218285_s_at | -0.1754 | 0.5743 | |
| GSE29001 | BDH2 | 56898 | 218285_s_at | -0.4020 | 0.1035 | |
| GSE38129 | BDH2 | 56898 | 218285_s_at | -0.5456 | 0.0003 | |
| GSE45670 | BDH2 | 56898 | 218285_s_at | -0.8040 | 0.0000 | |
| GSE63941 | BDH2 | 56898 | 218285_s_at | -2.3080 | 0.0111 | |
| GSE77861 | BDH2 | 56898 | 218285_s_at | -0.7364 | 0.0066 | |
| GSE97050 | BDH2 | 56898 | A_24_P80500 | -0.2200 | 0.3322 | |
| SRP007169 | BDH2 | 56898 | RNAseq | -1.1633 | 0.0030 | |
| SRP008496 | BDH2 | 56898 | RNAseq | -0.8543 | 0.0013 | |
| SRP064894 | BDH2 | 56898 | RNAseq | -0.2633 | 0.1327 | |
| SRP133303 | BDH2 | 56898 | RNAseq | -0.4658 | 0.0174 | |
| SRP159526 | BDH2 | 56898 | RNAseq | -0.6844 | 0.0340 | |
| SRP193095 | BDH2 | 56898 | RNAseq | -1.0218 | 0.0000 | |
| SRP219564 | BDH2 | 56898 | RNAseq | -0.5003 | 0.1398 | |
| TCGA | BDH2 | 56898 | RNAseq | -0.4955 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by BDH2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of BDH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BDH2 | 56898 | 0 | 12 | 18 | |
| GSE20123 | BDH2 | 56898 | 0 | 12 | 18 | |
| GSE43470 | BDH2 | 56898 | 0 | 13 | 30 | |
| GSE46452 | BDH2 | 56898 | 1 | 36 | 22 | |
| GSE47630 | BDH2 | 56898 | 0 | 20 | 20 | |
| GSE54993 | BDH2 | 56898 | 9 | 0 | 61 | |
| GSE54994 | BDH2 | 56898 | 1 | 10 | 42 | |
| GSE60625 | BDH2 | 56898 | 0 | 3 | 8 | |
| GSE74703 | BDH2 | 56898 | 0 | 11 | 25 | |
| GSE74704 | BDH2 | 56898 | 0 | 6 | 14 | |
| TCGA | BDH2 | 56898 | 8 | 40 | 48 |
Total number of gains: 19; Total number of losses: 163; Total Number of normals: 306.
Somatic mutations of BDH2:
Generating mutation plots.
Highly correlated genes for BDH2:
Showing top 20/986 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BDH2 | PRKAB1 | 0.762607 | 3 | 0 | 3 |
| BDH2 | LRRK2 | 0.760688 | 5 | 0 | 5 |
| BDH2 | GPBP1 | 0.758075 | 4 | 0 | 3 |
| BDH2 | GNL3 | 0.754976 | 3 | 0 | 3 |
| BDH2 | NDUFAF2 | 0.749369 | 3 | 0 | 3 |
| BDH2 | ABCB7 | 0.74681 | 3 | 0 | 3 |
| BDH2 | PXK | 0.736425 | 3 | 0 | 3 |
| BDH2 | CSDE1 | 0.735526 | 6 | 0 | 6 |
| BDH2 | EEPD1 | 0.735246 | 3 | 0 | 3 |
| BDH2 | C7 | 0.734196 | 4 | 0 | 4 |
| BDH2 | ARHGAP31 | 0.728149 | 3 | 0 | 3 |
| BDH2 | TK2 | 0.727292 | 3 | 0 | 3 |
| BDH2 | WDR11 | 0.726615 | 3 | 0 | 3 |
| BDH2 | EPB41L4A-AS1 | 0.726371 | 3 | 0 | 3 |
| BDH2 | TRIM5 | 0.725789 | 3 | 0 | 3 |
| BDH2 | CYP4V2 | 0.722541 | 3 | 0 | 3 |
| BDH2 | P2RY12 | 0.72069 | 3 | 0 | 3 |
| BDH2 | NTN4 | 0.720634 | 3 | 0 | 3 |
| BDH2 | GTF2B | 0.716907 | 3 | 0 | 3 |
| BDH2 | BRWD3 | 0.715383 | 3 | 0 | 3 |
For details and further investigation, click here
