| Full name: mediator complex subunit 31 | Alias Symbol: CGI-125|Soh1 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 51003 | HGNC ID: HGNC:24260 | Ensembl Gene: ENSG00000108590 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MED31:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MED31 | 51003 | 222867_s_at | 0.0087 | 0.9898 | |
| GSE20347 | MED31 | 51003 | 219318_x_at | -0.2541 | 0.0075 | |
| GSE23400 | MED31 | 51003 | 219318_x_at | -0.2195 | 0.0000 | |
| GSE26886 | MED31 | 51003 | 222867_s_at | -0.1621 | 0.4190 | |
| GSE29001 | MED31 | 51003 | 219318_x_at | -0.5392 | 0.0001 | |
| GSE38129 | MED31 | 51003 | 219318_x_at | -0.3003 | 0.0002 | |
| GSE45670 | MED31 | 51003 | 222867_s_at | 0.1525 | 0.3173 | |
| GSE63941 | MED31 | 51003 | 222867_s_at | 0.1114 | 0.8106 | |
| GSE77861 | MED31 | 51003 | 222867_s_at | 0.0736 | 0.8102 | |
| GSE97050 | MED31 | 51003 | A_33_P3362526 | -0.0532 | 0.9191 | |
| SRP007169 | MED31 | 51003 | RNAseq | -0.4579 | 0.3306 | |
| SRP008496 | MED31 | 51003 | RNAseq | -0.6018 | 0.0421 | |
| SRP064894 | MED31 | 51003 | RNAseq | -0.2880 | 0.0482 | |
| SRP133303 | MED31 | 51003 | RNAseq | -0.1981 | 0.2573 | |
| SRP159526 | MED31 | 51003 | RNAseq | -0.3603 | 0.0794 | |
| SRP193095 | MED31 | 51003 | RNAseq | -0.3348 | 0.0304 | |
| SRP219564 | MED31 | 51003 | RNAseq | -0.6550 | 0.1226 | |
| TCGA | MED31 | 51003 | RNAseq | 0.2157 | 0.0152 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MED31 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MED31:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MED31 | 51003 | 4 | 2 | 24 | |
| GSE20123 | MED31 | 51003 | 4 | 3 | 23 | |
| GSE43470 | MED31 | 51003 | 1 | 6 | 36 | |
| GSE46452 | MED31 | 51003 | 34 | 1 | 24 | |
| GSE47630 | MED31 | 51003 | 7 | 1 | 32 | |
| GSE54993 | MED31 | 51003 | 4 | 3 | 63 | |
| GSE54994 | MED31 | 51003 | 5 | 8 | 40 | |
| GSE60625 | MED31 | 51003 | 4 | 0 | 7 | |
| GSE74703 | MED31 | 51003 | 1 | 3 | 32 | |
| GSE74704 | MED31 | 51003 | 2 | 1 | 17 | |
| TCGA | MED31 | 51003 | 18 | 20 | 58 |
Total number of gains: 84; Total number of losses: 48; Total Number of normals: 356.
Somatic mutations of MED31:
Generating mutation plots.
Highly correlated genes for MED31:
Showing top 20/300 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MED31 | CSHL1 | 0.721873 | 4 | 0 | 4 |
| MED31 | GALR3 | 0.709457 | 4 | 0 | 4 |
| MED31 | SLC28A2 | 0.703378 | 4 | 0 | 4 |
| MED31 | KRT32 | 0.695446 | 4 | 0 | 4 |
| MED31 | HTR3B | 0.690983 | 4 | 0 | 4 |
| MED31 | SSTR4 | 0.681368 | 4 | 0 | 4 |
| MED31 | CCIN | 0.677936 | 4 | 0 | 4 |
| MED31 | GPR37L1 | 0.677601 | 4 | 0 | 4 |
| MED31 | UPK2 | 0.677143 | 4 | 0 | 4 |
| MED31 | SPX | 0.675641 | 4 | 0 | 4 |
| MED31 | ZBED2 | 0.674734 | 4 | 0 | 3 |
| MED31 | GLYAT | 0.67222 | 4 | 0 | 3 |
| MED31 | DUSP13 | 0.670065 | 4 | 0 | 3 |
| MED31 | CCDC7 | 0.661909 | 4 | 0 | 4 |
| MED31 | TAAR5 | 0.659321 | 4 | 0 | 4 |
| MED31 | HBZ | 0.658355 | 4 | 0 | 4 |
| MED31 | PDE6A | 0.656902 | 4 | 0 | 4 |
| MED31 | GSN-AS1 | 0.65592 | 4 | 0 | 3 |
| MED31 | TPMT | 0.65319 | 3 | 0 | 3 |
| MED31 | MAGEA8 | 0.650532 | 3 | 0 | 3 |
For details and further investigation, click here
