GALR3

 

Full name: galanin receptor 3 Alias Symbol: 
Type: protein-coding gene Cytoband: 22q13.1
Entrez ID: 8484 HGNC ID: HGNC:4134 Ensembl Gene: ENSG00000128310 OMIM ID: 603692
Drug and gene relationship at DGIdb

 

Expression of GALR3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GALR3 8484 33579_i_at -0.4853 0.0757
GSE20347 GALR3 8484 33579_i_at -0.5398 0.0000
GSE23400 GALR3 8484 33579_i_at -0.3018 0.0000
GSE26886 GALR3 8484 33579_i_at -0.7217 0.0001
GSE29001 GALR3 8484 33579_i_at -0.5262 0.0006
GSE38129 GALR3 8484 33579_i_at -0.4438 0.0001
GSE45670 GALR3 8484 33579_i_at -0.1963 0.1356
GSE53622 GALR3 8484 116305 -0.2347 0.0000
GSE53624 GALR3 8484 116305 -0.1134 0.0359
GSE63941 GALR3 8484 33579_i_at 0.0880 0.5383
GSE77861 GALR3 8484 33579_i_at -0.5803 0.0023
GSE97050 GALR3 8484 A_23_P256663 0.0160 0.9520
TCGA GALR3 8484 RNAseq 1.6903 0.0158

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by GALR3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GALR3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GALR3 8484 6 5 19
GSE20123 GALR3 8484 6 4 20
GSE43470 GALR3 8484 4 6 33
GSE46452 GALR3 8484 32 2 25
GSE47630 GALR3 8484 9 4 27
GSE54993 GALR3 8484 3 6 61
GSE54994 GALR3 8484 9 8 36
GSE60625 GALR3 8484 5 0 6
GSE74703 GALR3 8484 4 4 28
GSE74704 GALR3 8484 3 2 15
TCGA GALR3 8484 27 15 54

Total number of gains: 108; Total number of losses: 56; Total Number of normals: 324.  


 

Somatic mutations of GALR3:

 

Generating mutation plots.

 

Highly correlated genes for GALR3:

 

Showing top 20/1212 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GALR3SNORA680.806064404
GALR3C5orf66-AS10.785647404
GALR3INO80C0.779943505
GALR3LCN80.771601404
GALR3DENND2C0.769817404
GALR3SLC35C10.763965909
GALR3SFTA20.763614404
GALR3GDPD30.760956808
GALR3A2ML10.756919404
GALR3ABCC60.755577303
GALR3TMPRSS11B0.75022404
GALR3CAPN140.747258404
GALR3IL17RC0.74589411010
GALR3ANKRD220.742466404
GALR3PTK60.737077909
GALR3CLIC30.73623808
GALR3MAPK30.734199908
GALR3SRRM30.73324303
GALR3LINC012100.7326303
GALR3CBR3-AS10.728438404

For details and further investigation, click here