NLRP11

 

Full name: NLR family pyrin domain containing 11 Alias Symbol: PYPAF6|NOD17|PAN10|CLR19.6
Type: protein-coding gene Cytoband: 19q13.43
Entrez ID: 204801 HGNC ID: HGNC:22945 Ensembl Gene: ENSG00000179873 OMIM ID: 609664
Drug and gene relationship at DGIdb

 

Expression of NLRP11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NLRP11 204801 1552531_a_at 0.1295 0.4605
GSE26886 NLRP11 204801 1552531_a_at 0.2200 0.2269
GSE45670 NLRP11 204801 1552531_a_at 0.2057 0.1514
GSE53622 NLRP11 204801 46030 0.0941 0.6277
GSE53624 NLRP11 204801 95068 0.0137 0.9137
GSE63941 NLRP11 204801 1552531_a_at 0.1583 0.4095
GSE77861 NLRP11 204801 1552531_a_at -0.1845 0.0520
TCGA NLRP11 204801 RNAseq -1.4928 0.2164

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by NLRP11 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NLRP11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NLRP11 204801 3 4 23
GSE20123 NLRP11 204801 3 3 24
GSE43470 NLRP11 204801 3 9 31
GSE46452 NLRP11 204801 45 1 13
GSE47630 NLRP11 204801 8 6 26
GSE54993 NLRP11 204801 17 4 49
GSE54994 NLRP11 204801 5 13 35
GSE60625 NLRP11 204801 9 0 2
GSE74703 NLRP11 204801 3 6 27
GSE74704 NLRP11 204801 3 1 16
TCGA NLRP11 204801 19 15 62

Total number of gains: 118; Total number of losses: 62; Total Number of normals: 308.  

 

Somatic mutations of NLRP11:

 

Generating mutation plots.

 

Highly correlated genes for NLRP11:

 

Showing all 14 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NLRP11CEP1280.711349303
NLRP11MEP1A0.675534303
NLRP11LINC005250.661328303
NLRP11DEFB1260.622047303
NLRP11FCAMR0.590877403
NLRP11SSX30.570537403
NLRP11ZNF4450.564637303
NLRP11FAM47B0.56097303
NLRP11PRSS500.558855303
NLRP11TMPO-AS10.556361503
NLRP11RAD21L10.551854303
NLRP11SPATA80.546525403
NLRP11JRK0.529807503
NLRP11CDH240.525017503

For details and further investigation, click here