| Full name: zinc finger protein 445 | Alias Symbol: ZKSCAN15|ZSCAN47 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 353274 | HGNC ID: HGNC:21018 | Ensembl Gene: ENSG00000185219 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF445:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF445 | 353274 | 229766_at | 0.1672 | 0.5702 | |
| GSE26886 | ZNF445 | 353274 | 233992_x_at | -0.3090 | 0.0340 | |
| GSE45670 | ZNF445 | 353274 | 233992_x_at | -0.1003 | 0.2329 | |
| GSE53622 | ZNF445 | 353274 | 57120 | 0.6382 | 0.0000 | |
| GSE53624 | ZNF445 | 353274 | 57120 | 0.3786 | 0.0002 | |
| GSE63941 | ZNF445 | 353274 | 229766_at | -0.5463 | 0.0708 | |
| GSE77861 | ZNF445 | 353274 | 233992_x_at | -0.1841 | 0.0362 | |
| GSE97050 | ZNF445 | 353274 | A_33_P3420035 | -0.1599 | 0.5133 | |
| SRP007169 | ZNF445 | 353274 | RNAseq | 1.2284 | 0.0102 | |
| SRP008496 | ZNF445 | 353274 | RNAseq | 1.0989 | 0.0007 | |
| SRP064894 | ZNF445 | 353274 | RNAseq | 0.0489 | 0.7989 | |
| SRP133303 | ZNF445 | 353274 | RNAseq | -0.1299 | 0.1170 | |
| SRP159526 | ZNF445 | 353274 | RNAseq | 0.1717 | 0.4473 | |
| SRP193095 | ZNF445 | 353274 | RNAseq | 0.0714 | 0.5217 | |
| SRP219564 | ZNF445 | 353274 | RNAseq | -0.1021 | 0.7095 | |
| TCGA | ZNF445 | 353274 | RNAseq | -0.2514 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZNF445 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF445:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF445 | 353274 | 0 | 19 | 11 | |
| GSE20123 | ZNF445 | 353274 | 0 | 19 | 11 | |
| GSE43470 | ZNF445 | 353274 | 0 | 21 | 22 | |
| GSE46452 | ZNF445 | 353274 | 2 | 17 | 40 | |
| GSE47630 | ZNF445 | 353274 | 1 | 24 | 15 | |
| GSE54993 | ZNF445 | 353274 | 7 | 2 | 61 | |
| GSE54994 | ZNF445 | 353274 | 0 | 35 | 18 | |
| GSE60625 | ZNF445 | 353274 | 5 | 0 | 6 | |
| GSE74703 | ZNF445 | 353274 | 0 | 16 | 20 | |
| GSE74704 | ZNF445 | 353274 | 0 | 13 | 7 | |
| TCGA | ZNF445 | 353274 | 1 | 74 | 21 |
Total number of gains: 16; Total number of losses: 240; Total Number of normals: 232.
Somatic mutations of ZNF445:
Generating mutation plots.
Highly correlated genes for ZNF445:
Showing top 20/168 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF445 | ALG11 | 0.925623 | 3 | 0 | 3 |
| ZNF445 | ASB3 | 0.847697 | 3 | 0 | 3 |
| ZNF445 | OR2T33 | 0.841402 | 3 | 0 | 3 |
| ZNF445 | SZT2 | 0.839474 | 4 | 0 | 4 |
| ZNF445 | OR2AT4 | 0.817529 | 3 | 0 | 3 |
| ZNF445 | SPEG | 0.813692 | 3 | 0 | 3 |
| ZNF445 | USP17L2 | 0.804616 | 3 | 0 | 3 |
| ZNF445 | OR1L6 | 0.796299 | 3 | 0 | 3 |
| ZNF445 | KRTAP12-2 | 0.792162 | 3 | 0 | 3 |
| ZNF445 | SLC26A5 | 0.784124 | 3 | 0 | 3 |
| ZNF445 | ARL17A | 0.777845 | 3 | 0 | 3 |
| ZNF445 | SKI | 0.766743 | 3 | 0 | 3 |
| ZNF445 | CDKN2C | 0.757012 | 3 | 0 | 3 |
| ZNF445 | ZNF248 | 0.756519 | 4 | 0 | 3 |
| ZNF445 | SLC4A8 | 0.753005 | 3 | 0 | 3 |
| ZNF445 | TSEN34 | 0.741177 | 3 | 0 | 3 |
| ZNF445 | TAS2R43 | 0.732104 | 3 | 0 | 3 |
| ZNF445 | VAX2 | 0.722899 | 4 | 0 | 4 |
| ZNF445 | KRTAP10-9 | 0.718432 | 3 | 0 | 3 |
| ZNF445 | CLK4 | 0.714951 | 3 | 0 | 3 |
For details and further investigation, click here
