| Full name: RAD21 cohesin complex component like 1 | Alias Symbol: dJ545L17.2|RAD21L | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 642636 | HGNC ID: HGNC:16271 | Ensembl Gene: ENSG00000244588 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RAD21L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAD21L1 | 642636 | 215917_at | 0.0608 | 0.7753 | |
| GSE20347 | RAD21L1 | 642636 | 215917_at | -0.0116 | 0.8419 | |
| GSE23400 | RAD21L1 | 642636 | 215917_at | -0.0094 | 0.5344 | |
| GSE26886 | RAD21L1 | 642636 | 215917_at | 0.0498 | 0.6610 | |
| GSE29001 | RAD21L1 | 642636 | 215917_at | -0.0207 | 0.8295 | |
| GSE38129 | RAD21L1 | 642636 | 215917_at | -0.0397 | 0.3431 | |
| GSE45670 | RAD21L1 | 642636 | 215917_at | 0.0263 | 0.7931 | |
| GSE53622 | RAD21L1 | 642636 | 90590 | -0.9721 | 0.0000 | |
| GSE53624 | RAD21L1 | 642636 | 90590 | -1.3922 | 0.0000 | |
| GSE63941 | RAD21L1 | 642636 | 215917_at | 0.0061 | 0.9651 | |
| GSE77861 | RAD21L1 | 642636 | 215917_at | -0.1498 | 0.0603 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RAD21L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAD21L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAD21L1 | 642636 | 12 | 4 | 14 | |
| GSE20123 | RAD21L1 | 642636 | 13 | 4 | 13 | |
| GSE43470 | RAD21L1 | 642636 | 11 | 1 | 31 | |
| GSE46452 | RAD21L1 | 642636 | 26 | 1 | 32 | |
| GSE47630 | RAD21L1 | 642636 | 19 | 4 | 17 | |
| GSE54993 | RAD21L1 | 642636 | 2 | 14 | 54 | |
| GSE54994 | RAD21L1 | 642636 | 24 | 2 | 27 | |
| GSE60625 | RAD21L1 | 642636 | 0 | 0 | 11 | |
| GSE74703 | RAD21L1 | 642636 | 10 | 1 | 25 | |
| GSE74704 | RAD21L1 | 642636 | 8 | 2 | 10 | |
| TCGA | RAD21L1 | 642636 | 40 | 11 | 45 |
Total number of gains: 165; Total number of losses: 44; Total Number of normals: 279.
Somatic mutations of RAD21L1:
Generating mutation plots.
Highly correlated genes for RAD21L1:
Showing top 20/176 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAD21L1 | SDR9C7 | 0.782433 | 3 | 0 | 3 |
| RAD21L1 | TMEM79 | 0.781214 | 3 | 0 | 3 |
| RAD21L1 | SBSN | 0.755549 | 3 | 0 | 3 |
| RAD21L1 | PLIN3 | 0.745472 | 3 | 0 | 3 |
| RAD21L1 | SLC13A4 | 0.743297 | 3 | 0 | 3 |
| RAD21L1 | METRNL | 0.731757 | 3 | 0 | 3 |
| RAD21L1 | KLK13 | 0.716812 | 3 | 0 | 3 |
| RAD21L1 | KLK12 | 0.715958 | 3 | 0 | 3 |
| RAD21L1 | TOM1 | 0.714424 | 3 | 0 | 3 |
| RAD21L1 | CRYBB3 | 0.709773 | 3 | 0 | 3 |
| RAD21L1 | PLEKHN1 | 0.708352 | 3 | 0 | 3 |
| RAD21L1 | GGT6 | 0.706377 | 3 | 0 | 3 |
| RAD21L1 | LRRFIP2 | 0.705477 | 3 | 0 | 3 |
| RAD21L1 | YOD1 | 0.703978 | 3 | 0 | 3 |
| RAD21L1 | ANKRD31 | 0.698305 | 3 | 0 | 3 |
| RAD21L1 | MAL2 | 0.697903 | 3 | 0 | 3 |
| RAD21L1 | SLC16A6 | 0.697185 | 3 | 0 | 3 |
| RAD21L1 | CWH43 | 0.694793 | 3 | 0 | 3 |
| RAD21L1 | KLHL10 | 0.690805 | 3 | 0 | 3 |
| RAD21L1 | LY6G6C | 0.690423 | 3 | 0 | 3 |
For details and further investigation, click here
