| Full name: defensin beta 126 | Alias Symbol: bA530N10.1|DEFB-26 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 81623 | HGNC ID: HGNC:15900 | Ensembl Gene: ENSG00000125788 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DEFB126:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DEFB126 | 81623 | 221414_s_at | 0.4547 | 0.2602 | |
| GSE20347 | DEFB126 | 81623 | 221414_s_at | 0.0703 | 0.4490 | |
| GSE23400 | DEFB126 | 81623 | 221414_s_at | -0.0090 | 0.8930 | |
| GSE26886 | DEFB126 | 81623 | 221414_s_at | 0.8373 | 0.0059 | |
| GSE29001 | DEFB126 | 81623 | 221414_s_at | 0.2951 | 0.1168 | |
| GSE38129 | DEFB126 | 81623 | 221414_s_at | 0.4165 | 0.0044 | |
| GSE45670 | DEFB126 | 81623 | 221414_s_at | 0.3695 | 0.0076 | |
| GSE53622 | DEFB126 | 81623 | 94723 | 0.7944 | 0.0000 | |
| GSE53624 | DEFB126 | 81623 | 94723 | 1.1856 | 0.0000 | |
| GSE63941 | DEFB126 | 81623 | 221414_s_at | 0.1282 | 0.7267 | |
| GSE77861 | DEFB126 | 81623 | 221414_s_at | 0.1396 | 0.4412 | |
| TCGA | DEFB126 | 81623 | RNAseq | 3.5939 | 0.0002 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DEFB126 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DEFB126:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DEFB126 | 81623 | 12 | 4 | 14 | |
| GSE20123 | DEFB126 | 81623 | 13 | 4 | 13 | |
| GSE43470 | DEFB126 | 81623 | 11 | 1 | 31 | |
| GSE46452 | DEFB126 | 81623 | 26 | 1 | 32 | |
| GSE47630 | DEFB126 | 81623 | 19 | 4 | 17 | |
| GSE54993 | DEFB126 | 81623 | 2 | 15 | 53 | |
| GSE54994 | DEFB126 | 81623 | 24 | 2 | 27 | |
| GSE60625 | DEFB126 | 81623 | 0 | 0 | 11 | |
| GSE74703 | DEFB126 | 81623 | 10 | 1 | 25 | |
| GSE74704 | DEFB126 | 81623 | 8 | 2 | 10 | |
| TCGA | DEFB126 | 81623 | 41 | 11 | 44 |
Total number of gains: 166; Total number of losses: 45; Total Number of normals: 277.
Somatic mutations of DEFB126:
Generating mutation plots.
Highly correlated genes for DEFB126:
Showing top 20/68 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DEFB126 | LINC01252 | 0.687552 | 3 | 0 | 3 |
| DEFB126 | KCNQ1OT1 | 0.687223 | 3 | 0 | 3 |
| DEFB126 | LIN28B | 0.644774 | 3 | 0 | 3 |
| DEFB126 | C11orf95 | 0.644739 | 3 | 0 | 3 |
| DEFB126 | HNRNPUL1 | 0.641131 | 3 | 0 | 3 |
| DEFB126 | RNF139-AS1 | 0.632829 | 3 | 0 | 3 |
| DEFB126 | FOXO1 | 0.62858 | 3 | 0 | 3 |
| DEFB126 | IGSF9 | 0.626017 | 3 | 0 | 3 |
| DEFB126 | NLRP11 | 0.622047 | 3 | 0 | 3 |
| DEFB126 | RALY-AS1 | 0.613725 | 3 | 0 | 3 |
| DEFB126 | GXYLT2 | 0.607203 | 4 | 0 | 3 |
| DEFB126 | TBC1D1 | 0.606648 | 3 | 0 | 3 |
| DEFB126 | HERC5 | 0.606609 | 3 | 0 | 3 |
| DEFB126 | CRTAM | 0.603696 | 4 | 0 | 3 |
| DEFB126 | HOXA11 | 0.600613 | 3 | 0 | 3 |
| DEFB126 | NUP210 | 0.595298 | 4 | 0 | 3 |
| DEFB126 | CHCHD7 | 0.595219 | 4 | 0 | 3 |
| DEFB126 | POLD1 | 0.593048 | 4 | 0 | 3 |
| DEFB126 | SLC39A3 | 0.591718 | 4 | 0 | 3 |
| DEFB126 | BIRC3 | 0.590367 | 3 | 0 | 3 |
For details and further investigation, click here
