| Full name: phosphoglycolate phosphatase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 283871 | HGNC ID: HGNC:8909 | Ensembl Gene: ENSG00000184207 | OMIM ID: 172280 |
| Drug and gene relationship at DGIdb | |||
Expression of PGP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PGP | 283871 | 222622_at | 0.7724 | 0.0742 | |
| GSE20347 | PGP | 283871 | 218410_s_at | 0.0573 | 0.6063 | |
| GSE23400 | PGP | 283871 | 218410_s_at | -0.1021 | 0.0093 | |
| GSE26886 | PGP | 283871 | 222622_at | 1.4462 | 0.0000 | |
| GSE29001 | PGP | 283871 | 218410_s_at | 0.0898 | 0.5342 | |
| GSE38129 | PGP | 283871 | 218410_s_at | 0.0210 | 0.7987 | |
| GSE45670 | PGP | 283871 | 222622_at | 0.7299 | 0.0003 | |
| GSE53622 | PGP | 283871 | 85413 | 0.1020 | 0.1106 | |
| GSE53624 | PGP | 283871 | 85413 | 0.1527 | 0.0650 | |
| GSE63941 | PGP | 283871 | 222622_at | 0.5917 | 0.2039 | |
| GSE77861 | PGP | 283871 | 222622_at | 0.7922 | 0.0112 | |
| GSE97050 | PGP | 283871 | A_24_P942805 | -0.0658 | 0.7482 | |
| SRP007169 | PGP | 283871 | RNAseq | 0.6924 | 0.0801 | |
| SRP008496 | PGP | 283871 | RNAseq | 1.0754 | 0.0001 | |
| SRP064894 | PGP | 283871 | RNAseq | 1.0483 | 0.0002 | |
| SRP133303 | PGP | 283871 | RNAseq | 0.8489 | 0.0006 | |
| SRP159526 | PGP | 283871 | RNAseq | 1.0176 | 0.0019 | |
| SRP193095 | PGP | 283871 | RNAseq | 0.6160 | 0.0000 | |
| SRP219564 | PGP | 283871 | RNAseq | 0.6353 | 0.1033 | |
| TCGA | PGP | 283871 | RNAseq | 0.1161 | 0.0680 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by PGP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PGP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PGP | 283871 | 5 | 5 | 20 | |
| GSE20123 | PGP | 283871 | 5 | 4 | 21 | |
| GSE43470 | PGP | 283871 | 4 | 7 | 32 | |
| GSE46452 | PGP | 283871 | 38 | 1 | 20 | |
| GSE47630 | PGP | 283871 | 13 | 6 | 21 | |
| GSE54993 | PGP | 283871 | 3 | 5 | 62 | |
| GSE54994 | PGP | 283871 | 5 | 9 | 39 | |
| GSE60625 | PGP | 283871 | 4 | 0 | 7 | |
| GSE74703 | PGP | 283871 | 4 | 5 | 27 | |
| GSE74704 | PGP | 283871 | 3 | 2 | 15 | |
| TCGA | PGP | 283871 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of PGP:
Generating mutation plots.
Highly correlated genes for PGP:
Showing top 20/698 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PGP | KCNH3 | 0.847532 | 3 | 0 | 3 |
| PGP | DCDC1 | 0.836779 | 3 | 0 | 3 |
| PGP | STRC | 0.829644 | 3 | 0 | 3 |
| PGP | GYPE | 0.825683 | 3 | 0 | 3 |
| PGP | BBC3 | 0.813226 | 3 | 0 | 3 |
| PGP | ZNF329 | 0.805051 | 3 | 0 | 3 |
| PGP | C1QL2 | 0.805017 | 3 | 0 | 3 |
| PGP | YY2 | 0.803808 | 3 | 0 | 3 |
| PGP | ARHGAP21 | 0.79709 | 3 | 0 | 3 |
| PGP | TSPAN11 | 0.789055 | 3 | 0 | 3 |
| PGP | OR2T27 | 0.787107 | 3 | 0 | 3 |
| PGP | TMEM105 | 0.784188 | 3 | 0 | 3 |
| PGP | KIRREL2 | 0.782882 | 3 | 0 | 3 |
| PGP | TMEM229A | 0.781482 | 3 | 0 | 3 |
| PGP | PLA2G2C | 0.77933 | 3 | 0 | 3 |
| PGP | OR5A1 | 0.778848 | 3 | 0 | 3 |
| PGP | C20orf85 | 0.771518 | 3 | 0 | 3 |
| PGP | CMSS1 | 0.771109 | 4 | 0 | 4 |
| PGP | KCP | 0.768954 | 3 | 0 | 3 |
| PGP | SHARPIN | 0.76741 | 3 | 0 | 3 |
For details and further investigation, click here
