| Full name: phospholipase A2 group IIC | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.12 | ||
| Entrez ID: 391013 | HGNC ID: HGNC:9032 | Ensembl Gene: ENSG00000187980 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
PLA2G2C involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04014 | Ras signaling pathway | |
| hsa04270 | Vascular smooth muscle contraction |
Expression of PLA2G2C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | PLA2G2C | 391013 | 81575 | 0.2653 | 0.0074 | |
| GSE53624 | PLA2G2C | 391013 | 140411 | 0.0580 | 0.5696 | |
| GSE97050 | PLA2G2C | 391013 | A_33_P3344156 | -0.2126 | 0.3874 | |
| SRP219564 | PLA2G2C | 391013 | RNAseq | -3.5820 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PLA2G2C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLA2G2C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLA2G2C | 391013 | 0 | 5 | 25 | |
| GSE20123 | PLA2G2C | 391013 | 0 | 4 | 26 | |
| GSE43470 | PLA2G2C | 391013 | 0 | 8 | 35 | |
| GSE46452 | PLA2G2C | 391013 | 5 | 1 | 53 | |
| GSE47630 | PLA2G2C | 391013 | 8 | 3 | 29 | |
| GSE54993 | PLA2G2C | 391013 | 3 | 1 | 66 | |
| GSE54994 | PLA2G2C | 391013 | 11 | 4 | 38 | |
| GSE60625 | PLA2G2C | 391013 | 0 | 0 | 11 | |
| GSE74703 | PLA2G2C | 391013 | 0 | 5 | 31 | |
| GSE74704 | PLA2G2C | 391013 | 0 | 0 | 20 | |
| TCGA | PLA2G2C | 391013 | 11 | 21 | 64 |
Total number of gains: 38; Total number of losses: 52; Total Number of normals: 398.
Somatic mutations of PLA2G2C:
Generating mutation plots.
Highly correlated genes for PLA2G2C:
Showing top 20/300 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLA2G2C | CLDN9 | 0.886821 | 3 | 0 | 3 |
| PLA2G2C | CLTCL1 | 0.872494 | 3 | 0 | 3 |
| PLA2G2C | FOXE3 | 0.871876 | 3 | 0 | 3 |
| PLA2G2C | FBRSL1 | 0.864627 | 3 | 0 | 3 |
| PLA2G2C | TMEM105 | 0.862042 | 3 | 0 | 3 |
| PLA2G2C | SIM1 | 0.859754 | 3 | 0 | 3 |
| PLA2G2C | SLC26A1 | 0.858624 | 3 | 0 | 3 |
| PLA2G2C | KCNH3 | 0.85293 | 3 | 0 | 3 |
| PLA2G2C | SPACA3 | 0.849464 | 3 | 0 | 3 |
| PLA2G2C | BTNL2 | 0.849211 | 3 | 0 | 3 |
| PLA2G2C | GJD4 | 0.846094 | 3 | 0 | 3 |
| PLA2G2C | GRIK4 | 0.845482 | 3 | 0 | 3 |
| PLA2G2C | NKX6-3 | 0.844792 | 3 | 0 | 3 |
| PLA2G2C | WDR87 | 0.841932 | 3 | 0 | 3 |
| PLA2G2C | STRC | 0.840882 | 3 | 0 | 3 |
| PLA2G2C | DCDC1 | 0.840347 | 3 | 0 | 3 |
| PLA2G2C | KRTAP4-8 | 0.839222 | 3 | 0 | 3 |
| PLA2G2C | SERPINA10 | 0.839013 | 3 | 0 | 3 |
| PLA2G2C | CIB3 | 0.836815 | 3 | 0 | 3 |
| PLA2G2C | SLC22A31 | 0.83557 | 3 | 0 | 3 |
For details and further investigation, click here
