| Full name: stereocilin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q15.3 | ||
| Entrez ID: 161497 | HGNC ID: HGNC:16035 | Ensembl Gene: ENSG00000242866 | OMIM ID: 606440 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of STRC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | STRC | 161497 | 102664 | 0.2766 | 0.0038 | |
| GSE53624 | STRC | 161497 | 102664 | 0.0177 | 0.8842 | |
| GSE97050 | STRC | 161497 | A_23_P163238 | 0.0732 | 0.7144 | |
| SRP133303 | STRC | 161497 | RNAseq | 0.7740 | 0.0817 | |
| SRP159526 | STRC | 161497 | RNAseq | 1.1944 | 0.0708 | |
| SRP219564 | STRC | 161497 | RNAseq | 1.1666 | 0.0994 | |
| TCGA | STRC | 161497 | RNAseq | 0.3082 | 0.3278 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STRC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STRC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STRC | 161497 | 3 | 4 | 23 | |
| GSE20123 | STRC | 161497 | 3 | 5 | 22 | |
| GSE43470 | STRC | 161497 | 3 | 5 | 35 | |
| GSE46452 | STRC | 161497 | 3 | 7 | 49 | |
| GSE47630 | STRC | 161497 | 8 | 10 | 22 | |
| GSE54993 | STRC | 161497 | 4 | 6 | 60 | |
| GSE54994 | STRC | 161497 | 5 | 7 | 41 | |
| GSE60625 | STRC | 161497 | 4 | 0 | 7 | |
| GSE74703 | STRC | 161497 | 3 | 3 | 30 | |
| GSE74704 | STRC | 161497 | 2 | 2 | 16 | |
| TCGA | STRC | 161497 | 12 | 17 | 67 |
Total number of gains: 50; Total number of losses: 66; Total Number of normals: 372.
Somatic mutations of STRC:
Generating mutation plots.
Highly correlated genes for STRC:
Showing top 20/345 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STRC | GRIK4 | 0.910454 | 3 | 0 | 3 |
| STRC | KCNH3 | 0.907377 | 3 | 0 | 3 |
| STRC | CLTCL1 | 0.901855 | 3 | 0 | 3 |
| STRC | FBRSL1 | 0.896042 | 3 | 0 | 3 |
| STRC | TMEM105 | 0.891172 | 3 | 0 | 3 |
| STRC | SUN5 | 0.88862 | 3 | 0 | 3 |
| STRC | SPACA3 | 0.888362 | 3 | 0 | 3 |
| STRC | CNOT3 | 0.88719 | 3 | 0 | 3 |
| STRC | BTNL2 | 0.880498 | 3 | 0 | 3 |
| STRC | SERPINA10 | 0.876978 | 3 | 0 | 3 |
| STRC | WDR87 | 0.876973 | 3 | 0 | 3 |
| STRC | FOXE3 | 0.876843 | 3 | 0 | 3 |
| STRC | SLC22A31 | 0.876478 | 3 | 0 | 3 |
| STRC | SLC26A1 | 0.872497 | 3 | 0 | 3 |
| STRC | NKX6-3 | 0.87199 | 3 | 0 | 3 |
| STRC | GFRA4 | 0.870169 | 3 | 0 | 3 |
| STRC | DCDC1 | 0.869598 | 3 | 0 | 3 |
| STRC | CLDN9 | 0.868654 | 3 | 0 | 3 |
| STRC | AGRP | 0.866903 | 3 | 0 | 3 |
| STRC | ANKDD1A | 0.866362 | 3 | 0 | 3 |
For details and further investigation, click here
