GYPE

 

Full name: glycophorin E (MNS blood group) Alias Symbol: GPE|MNS
Type: protein-coding gene Cytoband: 4q31.21
Entrez ID: 2996 HGNC ID: HGNC:4705 Ensembl Gene: ENSG00000197465 OMIM ID: 138590
Drug and gene relationship at DGIdb

 

Expression of GYPE:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GYPE 2996 207854_at 0.0435 0.8476
GSE20347 GYPE 2996 207854_at 0.0114 0.8633
GSE23400 GYPE 2996 207854_at 0.0073 0.6057
GSE26886 GYPE 2996 207854_at 0.1133 0.2482
GSE29001 GYPE 2996 207854_at 0.0677 0.5905
GSE38129 GYPE 2996 207854_at -0.0248 0.6143
GSE45670 GYPE 2996 207854_at 0.1370 0.0708
GSE53622 GYPE 2996 51629 0.0803 0.2118
GSE53624 GYPE 2996 51629 0.2004 0.0675
GSE63941 GYPE 2996 207854_at -0.0618 0.5576
GSE77861 GYPE 2996 207854_at 0.0099 0.9219
GSE97050 GYPE 2996 A_23_P41304 0.1631 0.3810
SRP133303 GYPE 2996 RNAseq -0.6394 0.0337
TCGA GYPE 2996 RNAseq -1.2745 0.0034

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by GYPE expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GYPE:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GYPE 2996 0 12 18
GSE20123 GYPE 2996 0 12 18
GSE43470 GYPE 2996 2 11 30
GSE46452 GYPE 2996 1 36 22
GSE47630 GYPE 2996 0 22 18
GSE54993 GYPE 2996 10 0 60
GSE54994 GYPE 2996 2 11 40
GSE60625 GYPE 2996 0 1 10
GSE74703 GYPE 2996 1 10 25
GSE74704 GYPE 2996 0 6 14
TCGA GYPE 2996 13 30 53

Total number of gains: 29; Total number of losses: 151; Total Number of normals: 308.  


 

Somatic mutations of GYPE:

 

Generating mutation plots.

 

Highly correlated genes for GYPE:

 

Showing top 20/321 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GYPECIB30.827555303
GYPEPGP0.825683303
GYPEINSC0.817669303
GYPEOR2A50.811072303
GYPEC1QL20.800207303
GYPEDCDC10.795759303
GYPEGDPD50.794622303
GYPETMEM229A0.791425303
GYPEOR2T10.791071303
GYPESERPINA100.78705404
GYPEFBXO170.782679404
GYPEOR2T270.782279303
GYPESEC620.782136303
GYPEPABPN1L0.774058303
GYPEABCA20.772858303
GYPEOR5A10.767819303
GYPEBBC30.766921303
GYPEYY20.766286303
GYPEZNF2360.76377404
GYPERASL10B0.758482303

For details and further investigation, click here