| Full name: doublecortin domain containing 1 | Alias Symbol: FLJ46154 | ||
| Type: protein-coding gene | Cytoband: 11p14.1 | ||
| Entrez ID: 341019 | HGNC ID: HGNC:20625 | Ensembl Gene: ENSG00000170959 | OMIM ID: 608062 |
| Drug and gene relationship at DGIdb | |||
Expression of DCDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | DCDC1 | 341019 | 89746 | 0.3171 | 0.0006 | |
| GSE53624 | DCDC1 | 341019 | 89746 | 0.1246 | 0.2026 | |
| GSE97050 | DCDC1 | 341019 | A_33_P3346083 | -0.0023 | 0.9926 | |
| SRP133303 | DCDC1 | 341019 | RNAseq | 0.4216 | 0.1548 | |
| SRP159526 | DCDC1 | 341019 | RNAseq | 1.5607 | 0.0232 | |
| SRP193095 | DCDC1 | 341019 | RNAseq | 0.2942 | 0.1575 | |
| SRP219564 | DCDC1 | 341019 | RNAseq | 1.1879 | 0.1178 | |
| TCGA | DCDC1 | 341019 | RNAseq | 3.7622 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DCDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCDC1 | 341019 | 1 | 9 | 20 | |
| GSE20123 | DCDC1 | 341019 | 1 | 8 | 21 | |
| GSE43470 | DCDC1 | 341019 | 2 | 4 | 37 | |
| GSE46452 | DCDC1 | 341019 | 8 | 5 | 46 | |
| GSE47630 | DCDC1 | 341019 | 3 | 10 | 27 | |
| GSE54993 | DCDC1 | 341019 | 3 | 0 | 67 | |
| GSE54994 | DCDC1 | 341019 | 4 | 10 | 39 | |
| GSE60625 | DCDC1 | 341019 | 0 | 0 | 11 | |
| GSE74703 | DCDC1 | 341019 | 2 | 2 | 32 | |
| GSE74704 | DCDC1 | 341019 | 0 | 7 | 13 | |
| TCGA | DCDC1 | 341019 | 12 | 25 | 59 |
Total number of gains: 36; Total number of losses: 80; Total Number of normals: 372.
Somatic mutations of DCDC1:
Generating mutation plots.
Highly correlated genes for DCDC1:
Showing top 20/362 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCDC1 | CLTCL1 | 0.912601 | 3 | 0 | 3 |
| DCDC1 | NKX6-3 | 0.904087 | 3 | 0 | 3 |
| DCDC1 | KCNH3 | 0.897633 | 3 | 0 | 3 |
| DCDC1 | DEFB121 | 0.894457 | 3 | 0 | 3 |
| DCDC1 | CIB3 | 0.892721 | 3 | 0 | 3 |
| DCDC1 | FBRSL1 | 0.882404 | 3 | 0 | 3 |
| DCDC1 | SUN5 | 0.877292 | 3 | 0 | 3 |
| DCDC1 | CPLX2 | 0.872747 | 3 | 0 | 3 |
| DCDC1 | SLC39A5 | 0.872366 | 3 | 0 | 3 |
| DCDC1 | TNFAIP8L1 | 0.870936 | 3 | 0 | 3 |
| DCDC1 | BTNL2 | 0.870326 | 3 | 0 | 3 |
| DCDC1 | ZNF763 | 0.869821 | 3 | 0 | 3 |
| DCDC1 | STRC | 0.869598 | 3 | 0 | 3 |
| DCDC1 | GJD4 | 0.86841 | 3 | 0 | 3 |
| DCDC1 | CHST10 | 0.868315 | 3 | 0 | 3 |
| DCDC1 | CLDN9 | 0.867593 | 3 | 0 | 3 |
| DCDC1 | SERPINA10 | 0.867283 | 3 | 0 | 3 |
| DCDC1 | FFAR1 | 0.867043 | 3 | 0 | 3 |
| DCDC1 | CNOT3 | 0.86654 | 3 | 0 | 3 |
| DCDC1 | TXNDC2 | 0.866197 | 3 | 0 | 3 |
For details and further investigation, click here
