| Full name: selectin P ligand | Alias Symbol: PSGL-1|CD162 | ||
| Type: protein-coding gene | Cytoband: 12q24.11 | ||
| Entrez ID: 6404 | HGNC ID: HGNC:10722 | Ensembl Gene: ENSG00000110876 | OMIM ID: 600738 |
| Drug and gene relationship at DGIdb | |||
Expression of SELPLG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SELPLG | 6404 | 209879_at | 0.3739 | 0.6931 | |
| GSE20347 | SELPLG | 6404 | 209880_s_at | -0.1339 | 0.0463 | |
| GSE23400 | SELPLG | 6404 | 209879_at | 0.0852 | 0.1409 | |
| GSE26886 | SELPLG | 6404 | 209879_at | 0.1296 | 0.6753 | |
| GSE29001 | SELPLG | 6404 | 209879_at | 0.0407 | 0.9032 | |
| GSE38129 | SELPLG | 6404 | 209880_s_at | -0.1563 | 0.0524 | |
| GSE45670 | SELPLG | 6404 | 209879_at | -0.0144 | 0.9444 | |
| GSE53622 | SELPLG | 6404 | 4790 | 0.1475 | 0.0480 | |
| GSE53624 | SELPLG | 6404 | 4790 | 0.0240 | 0.8327 | |
| GSE63941 | SELPLG | 6404 | 209880_s_at | 0.6086 | 0.0002 | |
| GSE77861 | SELPLG | 6404 | 209880_s_at | -0.0753 | 0.6683 | |
| GSE97050 | SELPLG | 6404 | A_23_P64860 | 0.0399 | 0.8704 | |
| SRP007169 | SELPLG | 6404 | RNAseq | 0.8370 | 0.2523 | |
| SRP008496 | SELPLG | 6404 | RNAseq | 0.7307 | 0.1308 | |
| SRP064894 | SELPLG | 6404 | RNAseq | 0.9662 | 0.0069 | |
| SRP133303 | SELPLG | 6404 | RNAseq | 0.1441 | 0.4207 | |
| SRP159526 | SELPLG | 6404 | RNAseq | -0.0806 | 0.9169 | |
| SRP193095 | SELPLG | 6404 | RNAseq | 0.4104 | 0.0305 | |
| SRP219564 | SELPLG | 6404 | RNAseq | 1.2009 | 0.0035 | |
| TCGA | SELPLG | 6404 | RNAseq | 0.0898 | 0.4805 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SELPLG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SELPLG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SELPLG | 6404 | 5 | 3 | 22 | |
| GSE20123 | SELPLG | 6404 | 5 | 4 | 21 | |
| GSE43470 | SELPLG | 6404 | 2 | 1 | 40 | |
| GSE46452 | SELPLG | 6404 | 9 | 1 | 49 | |
| GSE47630 | SELPLG | 6404 | 9 | 1 | 30 | |
| GSE54993 | SELPLG | 6404 | 0 | 5 | 65 | |
| GSE54994 | SELPLG | 6404 | 4 | 2 | 47 | |
| GSE60625 | SELPLG | 6404 | 0 | 0 | 11 | |
| GSE74703 | SELPLG | 6404 | 2 | 0 | 34 | |
| GSE74704 | SELPLG | 6404 | 2 | 2 | 16 | |
| TCGA | SELPLG | 6404 | 21 | 10 | 65 |
Total number of gains: 59; Total number of losses: 29; Total Number of normals: 400.
Somatic mutations of SELPLG:
Generating mutation plots.
Highly correlated genes for SELPLG:
Showing top 20/374 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SELPLG | COPE | 0.828159 | 3 | 0 | 3 |
| SELPLG | PREX1 | 0.775391 | 5 | 0 | 5 |
| SELPLG | CALY | 0.766954 | 3 | 0 | 3 |
| SELPLG | FKBP4 | 0.762194 | 3 | 0 | 3 |
| SELPLG | SLC32A1 | 0.760171 | 3 | 0 | 3 |
| SELPLG | SCAF1 | 0.758862 | 3 | 0 | 3 |
| SELPLG | SPEG | 0.754633 | 3 | 0 | 3 |
| SELPLG | KRTAP12-2 | 0.747545 | 3 | 0 | 3 |
| SELPLG | RFXAP | 0.741226 | 3 | 0 | 3 |
| SELPLG | EPN1 | 0.735367 | 5 | 0 | 5 |
| SELPLG | ZC3H18 | 0.731784 | 4 | 0 | 4 |
| SELPLG | ALG11 | 0.731454 | 3 | 0 | 3 |
| SELPLG | SLC26A5 | 0.72986 | 3 | 0 | 3 |
| SELPLG | OR2AT4 | 0.729609 | 3 | 0 | 3 |
| SELPLG | PROP1 | 0.7237 | 4 | 0 | 4 |
| SELPLG | SH2B1 | 0.723522 | 3 | 0 | 3 |
| SELPLG | KIR3DL2 | 0.721495 | 3 | 0 | 3 |
| SELPLG | SLA | 0.720996 | 5 | 0 | 5 |
| SELPLG | TMCO6 | 0.715993 | 3 | 0 | 3 |
| SELPLG | UBA1 | 0.713613 | 3 | 0 | 3 |
For details and further investigation, click here
