| Full name: tRNA methyltransferase 12 homolog | Alias Symbol: FLJ20772|Trm12|TYW2 | ||
| Type: protein-coding gene | Cytoband: 8q24.13 | ||
| Entrez ID: 55039 | HGNC ID: HGNC:26091 | Ensembl Gene: ENSG00000183665 | OMIM ID: 611244 |
| Drug and gene relationship at DGIdb | |||
Expression of TRMT12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRMT12 | 55039 | 219299_at | 0.7023 | 0.2876 | |
| GSE20347 | TRMT12 | 55039 | 219299_at | 0.8916 | 0.0001 | |
| GSE23400 | TRMT12 | 55039 | 219299_at | 0.4465 | 0.0000 | |
| GSE26886 | TRMT12 | 55039 | 219299_at | 0.6036 | 0.0020 | |
| GSE29001 | TRMT12 | 55039 | 219299_at | 0.8211 | 0.0001 | |
| GSE38129 | TRMT12 | 55039 | 219299_at | 0.8957 | 0.0000 | |
| GSE45670 | TRMT12 | 55039 | 219299_at | 0.5830 | 0.0164 | |
| GSE53622 | TRMT12 | 55039 | 71686 | 0.6068 | 0.0000 | |
| GSE53624 | TRMT12 | 55039 | 71686 | 0.8641 | 0.0000 | |
| GSE63941 | TRMT12 | 55039 | 219299_at | 0.3049 | 0.5677 | |
| GSE77861 | TRMT12 | 55039 | 219299_at | 0.4760 | 0.0314 | |
| GSE97050 | TRMT12 | 55039 | A_23_P82913 | 0.1947 | 0.4691 | |
| SRP007169 | TRMT12 | 55039 | RNAseq | 0.5432 | 0.1757 | |
| SRP008496 | TRMT12 | 55039 | RNAseq | 1.2411 | 0.0018 | |
| SRP064894 | TRMT12 | 55039 | RNAseq | 0.8206 | 0.0004 | |
| SRP133303 | TRMT12 | 55039 | RNAseq | 0.7323 | 0.0000 | |
| SRP159526 | TRMT12 | 55039 | RNAseq | 0.6609 | 0.0056 | |
| SRP193095 | TRMT12 | 55039 | RNAseq | 0.6572 | 0.0000 | |
| SRP219564 | TRMT12 | 55039 | RNAseq | 0.4919 | 0.1330 | |
| TCGA | TRMT12 | 55039 | RNAseq | 0.1779 | 0.0367 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TRMT12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRMT12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRMT12 | 55039 | 19 | 0 | 11 | |
| GSE20123 | TRMT12 | 55039 | 20 | 0 | 10 | |
| GSE43470 | TRMT12 | 55039 | 22 | 0 | 21 | |
| GSE46452 | TRMT12 | 55039 | 28 | 0 | 31 | |
| GSE47630 | TRMT12 | 55039 | 24 | 0 | 16 | |
| GSE54993 | TRMT12 | 55039 | 0 | 21 | 49 | |
| GSE54994 | TRMT12 | 55039 | 36 | 1 | 16 | |
| GSE60625 | TRMT12 | 55039 | 0 | 4 | 7 | |
| GSE74703 | TRMT12 | 55039 | 19 | 0 | 17 | |
| GSE74704 | TRMT12 | 55039 | 13 | 0 | 7 | |
| TCGA | TRMT12 | 55039 | 68 | 1 | 27 |
Total number of gains: 249; Total number of losses: 27; Total Number of normals: 212.
Somatic mutations of TRMT12:
Generating mutation plots.
Highly correlated genes for TRMT12:
Showing top 20/1604 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRMT12 | TIGD1 | 0.792638 | 4 | 0 | 4 |
| TRMT12 | DUS3L | 0.782034 | 3 | 0 | 3 |
| TRMT12 | RLIM | 0.777131 | 3 | 0 | 3 |
| TRMT12 | CHD1 | 0.771777 | 3 | 0 | 3 |
| TRMT12 | NTPCR | 0.76724 | 4 | 0 | 4 |
| TRMT12 | COMMD2 | 0.766686 | 4 | 0 | 4 |
| TRMT12 | CBFA2T2 | 0.764691 | 3 | 0 | 3 |
| TRMT12 | PSPC1 | 0.763878 | 3 | 0 | 3 |
| TRMT12 | C9orf64 | 0.748952 | 3 | 0 | 3 |
| TRMT12 | PPP1R35 | 0.743143 | 3 | 0 | 3 |
| TRMT12 | LYSMD1 | 0.739878 | 3 | 0 | 3 |
| TRMT12 | ZNF707 | 0.738215 | 3 | 0 | 3 |
| TRMT12 | ATP6V1C1 | 0.731351 | 11 | 0 | 11 |
| TRMT12 | WDYHV1 | 0.72999 | 12 | 0 | 12 |
| TRMT12 | TRIB1 | 0.724594 | 3 | 0 | 3 |
| TRMT12 | ARNT | 0.719443 | 3 | 0 | 3 |
| TRMT12 | KTI12 | 0.71745 | 3 | 0 | 3 |
| TRMT12 | ZNF496 | 0.717263 | 4 | 0 | 3 |
| TRMT12 | KIN | 0.716688 | 3 | 0 | 3 |
| TRMT12 | IQCK | 0.714892 | 3 | 0 | 3 |
For details and further investigation, click here
