| Full name: zinc finger and BTB domain containing 12 | Alias Symbol: G10|NG35|D6S59E | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 221527 | HGNC ID: HGNC:19066 | Ensembl Gene: ENSG00000204366 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZBTB12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB12 | 221527 | 233843_at | 0.0240 | 0.9484 | |
| GSE26886 | ZBTB12 | 221527 | 233843_at | -0.0057 | 0.9669 | |
| GSE45670 | ZBTB12 | 221527 | 233843_at | 0.1853 | 0.0348 | |
| GSE53622 | ZBTB12 | 221527 | 52599 | 0.4526 | 0.0009 | |
| GSE53624 | ZBTB12 | 221527 | 52599 | 0.5227 | 0.0000 | |
| GSE63941 | ZBTB12 | 221527 | 233843_at | 0.0675 | 0.7608 | |
| GSE77861 | ZBTB12 | 221527 | 233843_at | 0.0030 | 0.9867 | |
| GSE97050 | ZBTB12 | 221527 | A_23_P111155 | 0.0292 | 0.9029 | |
| SRP007169 | ZBTB12 | 221527 | RNAseq | 0.2829 | 0.6953 | |
| SRP064894 | ZBTB12 | 221527 | RNAseq | 0.1638 | 0.4548 | |
| SRP133303 | ZBTB12 | 221527 | RNAseq | -0.2251 | 0.1407 | |
| SRP159526 | ZBTB12 | 221527 | RNAseq | 0.9440 | 0.0287 | |
| SRP193095 | ZBTB12 | 221527 | RNAseq | 0.0566 | 0.7294 | |
| SRP219564 | ZBTB12 | 221527 | RNAseq | 0.3811 | 0.2840 | |
| TCGA | ZBTB12 | 221527 | RNAseq | 0.3905 | 0.0045 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZBTB12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB12 | 221527 | 5 | 1 | 24 | |
| GSE20123 | ZBTB12 | 221527 | 5 | 1 | 24 | |
| GSE43470 | ZBTB12 | 221527 | 5 | 1 | 37 | |
| GSE46452 | ZBTB12 | 221527 | 1 | 10 | 48 | |
| GSE47630 | ZBTB12 | 221527 | 7 | 4 | 29 | |
| GSE54993 | ZBTB12 | 221527 | 2 | 1 | 67 | |
| GSE54994 | ZBTB12 | 221527 | 11 | 4 | 38 | |
| GSE60625 | ZBTB12 | 221527 | 0 | 1 | 10 | |
| GSE74703 | ZBTB12 | 221527 | 5 | 0 | 31 | |
| GSE74704 | ZBTB12 | 221527 | 2 | 0 | 18 | |
| TCGA | ZBTB12 | 221527 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of ZBTB12:
Generating mutation plots.
Highly correlated genes for ZBTB12:
Showing top 20/112 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB12 | RFXAP | 0.753959 | 3 | 0 | 3 |
| ZBTB12 | ZNF318 | 0.745725 | 3 | 0 | 3 |
| ZBTB12 | MTHFD1L | 0.741926 | 3 | 0 | 3 |
| ZBTB12 | SARDH | 0.733806 | 3 | 0 | 3 |
| ZBTB12 | ZNF496 | 0.722891 | 3 | 0 | 3 |
| ZBTB12 | NRGN | 0.719265 | 3 | 0 | 3 |
| ZBTB12 | HPCA | 0.711467 | 3 | 0 | 3 |
| ZBTB12 | PNN | 0.711241 | 3 | 0 | 3 |
| ZBTB12 | GAP43 | 0.710267 | 3 | 0 | 3 |
| ZBTB12 | ACAD11 | 0.702434 | 3 | 0 | 3 |
| ZBTB12 | MIF | 0.694703 | 3 | 0 | 3 |
| ZBTB12 | RBBP5 | 0.688683 | 3 | 0 | 3 |
| ZBTB12 | ZNF740 | 0.685751 | 3 | 0 | 3 |
| ZBTB12 | SP3 | 0.685514 | 3 | 0 | 3 |
| ZBTB12 | RAB4B | 0.67337 | 4 | 0 | 3 |
| ZBTB12 | UNC5A | 0.670441 | 3 | 0 | 3 |
| ZBTB12 | SPDYE3 | 0.667857 | 3 | 0 | 3 |
| ZBTB12 | ARL2 | 0.666799 | 3 | 0 | 3 |
| ZBTB12 | B3GNT4 | 0.665775 | 5 | 0 | 4 |
| ZBTB12 | KCNN1 | 0.664506 | 4 | 0 | 4 |
For details and further investigation, click here
