| Full name: RNA polymerase II subunit I | Alias Symbol: RPB9|hRPB14.5 | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 5438 | HGNC ID: HGNC:9196 | Ensembl Gene: ENSG00000105258 | OMIM ID: 180662 |
| Drug and gene relationship at DGIdb | |||
Expression of POLR2I:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POLR2I | 5438 | 212955_s_at | -0.2013 | 0.5107 | |
| GSE20347 | POLR2I | 5438 | 212955_s_at | -0.4215 | 0.0075 | |
| GSE23400 | POLR2I | 5438 | 212955_s_at | -0.0867 | 0.3473 | |
| GSE26886 | POLR2I | 5438 | 212955_s_at | 0.7243 | 0.0002 | |
| GSE29001 | POLR2I | 5438 | 212955_s_at | -0.3368 | 0.4287 | |
| GSE38129 | POLR2I | 5438 | 212955_s_at | -0.1642 | 0.2851 | |
| GSE45670 | POLR2I | 5438 | 212955_s_at | -0.1336 | 0.4447 | |
| GSE53622 | POLR2I | 5438 | 33567 | -0.2576 | 0.0003 | |
| GSE53624 | POLR2I | 5438 | 33567 | 0.0312 | 0.6351 | |
| GSE63941 | POLR2I | 5438 | 212955_s_at | 0.5104 | 0.3266 | |
| GSE77861 | POLR2I | 5438 | 212955_s_at | -0.0993 | 0.6910 | |
| GSE97050 | POLR2I | 5438 | A_23_P56256 | 0.0127 | 0.9611 | |
| SRP007169 | POLR2I | 5438 | RNAseq | -0.1865 | 0.7594 | |
| SRP008496 | POLR2I | 5438 | RNAseq | -0.4808 | 0.2309 | |
| SRP064894 | POLR2I | 5438 | RNAseq | 0.3416 | 0.3899 | |
| SRP133303 | POLR2I | 5438 | RNAseq | -0.0581 | 0.8179 | |
| SRP159526 | POLR2I | 5438 | RNAseq | 0.2417 | 0.5375 | |
| SRP193095 | POLR2I | 5438 | RNAseq | -0.3551 | 0.0166 | |
| SRP219564 | POLR2I | 5438 | RNAseq | -0.3232 | 0.1603 | |
| TCGA | POLR2I | 5438 | RNAseq | 0.0876 | 0.2122 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by POLR2I expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POLR2I:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POLR2I | 5438 | 8 | 4 | 18 | |
| GSE20123 | POLR2I | 5438 | 8 | 3 | 19 | |
| GSE43470 | POLR2I | 5438 | 3 | 7 | 33 | |
| GSE46452 | POLR2I | 5438 | 48 | 1 | 10 | |
| GSE47630 | POLR2I | 5438 | 9 | 5 | 26 | |
| GSE54993 | POLR2I | 5438 | 17 | 3 | 50 | |
| GSE54994 | POLR2I | 5438 | 6 | 9 | 38 | |
| GSE60625 | POLR2I | 5438 | 9 | 0 | 2 | |
| GSE74703 | POLR2I | 5438 | 3 | 4 | 29 | |
| GSE74704 | POLR2I | 5438 | 7 | 1 | 12 | |
| TCGA | POLR2I | 5438 | 22 | 10 | 64 |
Total number of gains: 140; Total number of losses: 47; Total Number of normals: 301.
Somatic mutations of POLR2I:
Generating mutation plots.
Highly correlated genes for POLR2I:
Showing top 20/288 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POLR2I | SUGP1 | 0.823918 | 3 | 0 | 3 |
| POLR2I | ZNF513 | 0.79262 | 3 | 0 | 3 |
| POLR2I | TSNARE1 | 0.775365 | 3 | 0 | 3 |
| POLR2I | RFXAP | 0.774351 | 3 | 0 | 3 |
| POLR2I | ALKBH6 | 0.758362 | 4 | 0 | 3 |
| POLR2I | RBM4 | 0.751229 | 3 | 0 | 3 |
| POLR2I | TSPAN31 | 0.745522 | 3 | 0 | 3 |
| POLR2I | INTS1 | 0.739421 | 3 | 0 | 3 |
| POLR2I | C19orf54 | 0.731434 | 3 | 0 | 3 |
| POLR2I | CHCHD6 | 0.730008 | 4 | 0 | 4 |
| POLR2I | TMEM129 | 0.721649 | 3 | 0 | 3 |
| POLR2I | ZNF362 | 0.720065 | 3 | 0 | 3 |
| POLR2I | COX6B1 | 0.718797 | 12 | 0 | 11 |
| POLR2I | PACSIN2 | 0.713929 | 3 | 0 | 3 |
| POLR2I | F8 | 0.713233 | 3 | 0 | 3 |
| POLR2I | EIF3K | 0.708903 | 12 | 0 | 12 |
| POLR2I | INO80E | 0.699736 | 3 | 0 | 3 |
| POLR2I | TMEM147 | 0.699632 | 12 | 0 | 12 |
| POLR2I | PRKCSH | 0.693113 | 3 | 0 | 3 |
| POLR2I | EIF2B1 | 0.689831 | 3 | 0 | 3 |
For details and further investigation, click here
