| Full name: zinc finger CCHC-type containing 3 | Alias Symbol: dJ1103G7.7 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 85364 | HGNC ID: HGNC:16230 | Ensembl Gene: ENSG00000247315 | OMIM ID: 618326 |
| Drug and gene relationship at DGIdb | |||
Expression of ZCCHC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZCCHC3 | 85364 | 225091_at | 0.3384 | 0.2587 | |
| GSE26886 | ZCCHC3 | 85364 | 225091_at | 0.5448 | 0.0013 | |
| GSE45670 | ZCCHC3 | 85364 | 225091_at | 0.2350 | 0.1760 | |
| GSE53622 | ZCCHC3 | 85364 | 79848 | 0.2157 | 0.0350 | |
| GSE53624 | ZCCHC3 | 85364 | 79848 | 0.3803 | 0.0006 | |
| GSE63941 | ZCCHC3 | 85364 | 225091_at | 0.2560 | 0.5695 | |
| GSE77861 | ZCCHC3 | 85364 | 225091_at | 0.5356 | 0.0451 | |
| GSE97050 | ZCCHC3 | 85364 | A_24_P399694 | 0.1771 | 0.5762 | |
| SRP007169 | ZCCHC3 | 85364 | RNAseq | 1.4222 | 0.0159 | |
| SRP064894 | ZCCHC3 | 85364 | RNAseq | 0.3341 | 0.0463 | |
| SRP133303 | ZCCHC3 | 85364 | RNAseq | 0.1062 | 0.4297 | |
| SRP159526 | ZCCHC3 | 85364 | RNAseq | 0.4787 | 0.0949 | |
| SRP193095 | ZCCHC3 | 85364 | RNAseq | 0.3889 | 0.0057 | |
| SRP219564 | ZCCHC3 | 85364 | RNAseq | 0.4159 | 0.1524 | |
| TCGA | ZCCHC3 | 85364 | RNAseq | -0.0414 | 0.4724 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZCCHC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZCCHC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZCCHC3 | 85364 | 12 | 4 | 14 | |
| GSE20123 | ZCCHC3 | 85364 | 13 | 4 | 13 | |
| GSE43470 | ZCCHC3 | 85364 | 11 | 1 | 31 | |
| GSE46452 | ZCCHC3 | 85364 | 26 | 1 | 32 | |
| GSE47630 | ZCCHC3 | 85364 | 19 | 4 | 17 | |
| GSE54993 | ZCCHC3 | 85364 | 2 | 15 | 53 | |
| GSE54994 | ZCCHC3 | 85364 | 24 | 2 | 27 | |
| GSE60625 | ZCCHC3 | 85364 | 0 | 0 | 11 | |
| GSE74703 | ZCCHC3 | 85364 | 10 | 1 | 25 | |
| GSE74704 | ZCCHC3 | 85364 | 8 | 2 | 10 | |
| TCGA | ZCCHC3 | 85364 | 41 | 11 | 44 |
Total number of gains: 166; Total number of losses: 45; Total Number of normals: 277.
Somatic mutations of ZCCHC3:
Generating mutation plots.
Highly correlated genes for ZCCHC3:
Showing top 20/937 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZCCHC3 | PAK1 | 0.838897 | 3 | 0 | 3 |
| ZCCHC3 | POLR3D | 0.825533 | 3 | 0 | 3 |
| ZCCHC3 | ZC3H18 | 0.811898 | 3 | 0 | 3 |
| ZCCHC3 | ZNF532 | 0.806837 | 4 | 0 | 4 |
| ZCCHC3 | MRPL9 | 0.804199 | 3 | 0 | 3 |
| ZCCHC3 | PHIP | 0.802437 | 3 | 0 | 3 |
| ZCCHC3 | PKIG | 0.796516 | 3 | 0 | 3 |
| ZCCHC3 | PTPN4 | 0.785865 | 3 | 0 | 3 |
| ZCCHC3 | SRSF6 | 0.779055 | 3 | 0 | 3 |
| ZCCHC3 | TBC1D8B | 0.772795 | 3 | 0 | 3 |
| ZCCHC3 | KLHL29 | 0.771642 | 3 | 0 | 3 |
| ZCCHC3 | RFXAP | 0.768628 | 3 | 0 | 3 |
| ZCCHC3 | UNC119 | 0.764494 | 3 | 0 | 3 |
| ZCCHC3 | SEC22C | 0.762943 | 3 | 0 | 3 |
| ZCCHC3 | PIK3R3 | 0.761534 | 3 | 0 | 3 |
| ZCCHC3 | CRKL | 0.758845 | 3 | 0 | 3 |
| ZCCHC3 | TSC22D1 | 0.754107 | 3 | 0 | 3 |
| ZCCHC3 | LARP6 | 0.751803 | 4 | 0 | 4 |
| ZCCHC3 | ZNF322 | 0.750212 | 3 | 0 | 3 |
| ZCCHC3 | OAF | 0.748997 | 3 | 0 | 3 |
For details and further investigation, click here
