| Full name: ALG10 alpha-1,2-glucosyltransferase | Alias Symbol: FLJ14751|DIE2|ALG10A | ||
| Type: protein-coding gene | Cytoband: 12p11.1 | ||
| Entrez ID: 84920 | HGNC ID: HGNC:23162 | Ensembl Gene: ENSG00000139133 | OMIM ID: 618355 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ALG10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALG10 | 84920 | 1552306_at | 0.5875 | 0.4574 | |
| GSE26886 | ALG10 | 84920 | 1552306_at | 0.4546 | 0.2153 | |
| GSE45670 | ALG10 | 84920 | 1552306_at | 1.3812 | 0.0000 | |
| GSE53622 | ALG10 | 84920 | 109720 | 0.7376 | 0.0000 | |
| GSE53624 | ALG10 | 84920 | 109720 | 0.9541 | 0.0000 | |
| GSE63941 | ALG10 | 84920 | 1552306_at | 0.9688 | 0.2579 | |
| GSE77861 | ALG10 | 84920 | 1552306_at | 0.1621 | 0.2480 | |
| GSE97050 | ALG10 | 84920 | A_33_P3230881 | 0.1883 | 0.5260 | |
| SRP007169 | ALG10 | 84920 | RNAseq | 1.4349 | 0.0113 | |
| SRP008496 | ALG10 | 84920 | RNAseq | 1.3323 | 0.0001 | |
| SRP064894 | ALG10 | 84920 | RNAseq | 0.5707 | 0.0148 | |
| SRP133303 | ALG10 | 84920 | RNAseq | 0.9174 | 0.0034 | |
| SRP159526 | ALG10 | 84920 | RNAseq | 1.1555 | 0.0060 | |
| SRP193095 | ALG10 | 84920 | RNAseq | 0.3259 | 0.0020 | |
| SRP219564 | ALG10 | 84920 | RNAseq | 0.8050 | 0.1690 | |
| TCGA | ALG10 | 84920 | RNAseq | 0.2173 | 0.0130 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by ALG10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALG10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALG10 | 84920 | 9 | 2 | 19 | |
| GSE20123 | ALG10 | 84920 | 9 | 2 | 19 | |
| GSE43470 | ALG10 | 84920 | 6 | 4 | 33 | |
| GSE46452 | ALG10 | 84920 | 10 | 1 | 48 | |
| GSE47630 | ALG10 | 84920 | 12 | 1 | 27 | |
| GSE54993 | ALG10 | 84920 | 1 | 9 | 60 | |
| GSE54994 | ALG10 | 84920 | 7 | 2 | 44 | |
| GSE60625 | ALG10 | 84920 | 0 | 1 | 10 | |
| GSE74703 | ALG10 | 84920 | 6 | 3 | 27 | |
| GSE74704 | ALG10 | 84920 | 5 | 1 | 14 | |
| TCGA | ALG10 | 84920 | 39 | 5 | 52 |
Total number of gains: 104; Total number of losses: 31; Total Number of normals: 353.
Somatic mutations of ALG10:
Generating mutation plots.
Highly correlated genes for ALG10:
Showing top 20/1186 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALG10 | RCC1 | 0.814509 | 3 | 0 | 3 |
| ALG10 | AIFM1 | 0.800759 | 3 | 0 | 3 |
| ALG10 | NIPA2 | 0.790382 | 3 | 0 | 3 |
| ALG10 | MRPL42 | 0.777154 | 4 | 0 | 4 |
| ALG10 | PALB2 | 0.770683 | 4 | 0 | 4 |
| ALG10 | NCF2 | 0.766392 | 3 | 0 | 3 |
| ALG10 | LSM10 | 0.764683 | 3 | 0 | 3 |
| ALG10 | MKRN1 | 0.756684 | 3 | 0 | 3 |
| ALG10 | RRP9 | 0.755055 | 3 | 0 | 3 |
| ALG10 | STOML1 | 0.753831 | 3 | 0 | 3 |
| ALG10 | AAGAB | 0.752898 | 3 | 0 | 3 |
| ALG10 | RNF26 | 0.749653 | 3 | 0 | 3 |
| ALG10 | PSMC3 | 0.749228 | 3 | 0 | 3 |
| ALG10 | GGCX | 0.749116 | 3 | 0 | 3 |
| ALG10 | POP5 | 0.749039 | 4 | 0 | 3 |
| ALG10 | COMMD4 | 0.748929 | 4 | 0 | 4 |
| ALG10 | MAGOHB | 0.747235 | 5 | 0 | 4 |
| ALG10 | DNAAF2 | 0.744389 | 3 | 0 | 3 |
| ALG10 | SMARCA5 | 0.742584 | 4 | 0 | 4 |
| ALG10 | RSBN1L | 0.739075 | 4 | 0 | 3 |
For details and further investigation, click here
