| Full name: ubiquitin specific peptidase 19 | Alias Symbol: KIAA0891|ZMYND9 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 10869 | HGNC ID: HGNC:12617 | Ensembl Gene: ENSG00000172046 | OMIM ID: 614471 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of USP19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP19 | 10869 | 226357_at | -0.0807 | 0.7536 | |
| GSE20347 | USP19 | 10869 | 214674_at | -0.1425 | 0.0673 | |
| GSE23400 | USP19 | 10869 | 214674_at | -0.0316 | 0.3727 | |
| GSE26886 | USP19 | 10869 | 226357_at | -0.0840 | 0.6292 | |
| GSE29001 | USP19 | 10869 | 214674_at | -0.2927 | 0.1168 | |
| GSE38129 | USP19 | 10869 | 214674_at | -0.1616 | 0.0145 | |
| GSE45670 | USP19 | 10869 | 226357_at | -0.1494 | 0.0439 | |
| GSE53622 | USP19 | 10869 | 51549 | -0.2605 | 0.0001 | |
| GSE53624 | USP19 | 10869 | 51549 | -0.1389 | 0.0157 | |
| GSE63941 | USP19 | 10869 | 226357_at | -0.2890 | 0.1812 | |
| GSE77861 | USP19 | 10869 | 226357_at | -0.1651 | 0.2952 | |
| GSE97050 | USP19 | 10869 | A_33_P3360301 | -0.1474 | 0.5458 | |
| SRP007169 | USP19 | 10869 | RNAseq | -0.3442 | 0.3884 | |
| SRP008496 | USP19 | 10869 | RNAseq | -0.5244 | 0.0219 | |
| SRP064894 | USP19 | 10869 | RNAseq | -0.3052 | 0.0090 | |
| SRP133303 | USP19 | 10869 | RNAseq | -0.4884 | 0.0008 | |
| SRP159526 | USP19 | 10869 | RNAseq | -0.3178 | 0.1076 | |
| SRP193095 | USP19 | 10869 | RNAseq | -0.2706 | 0.0065 | |
| SRP219564 | USP19 | 10869 | RNAseq | -0.4607 | 0.2224 | |
| TCGA | USP19 | 10869 | RNAseq | -0.1955 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USP19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP19 | 10869 | 0 | 18 | 12 | |
| GSE20123 | USP19 | 10869 | 0 | 19 | 11 | |
| GSE43470 | USP19 | 10869 | 0 | 18 | 25 | |
| GSE46452 | USP19 | 10869 | 2 | 16 | 41 | |
| GSE47630 | USP19 | 10869 | 1 | 24 | 15 | |
| GSE54993 | USP19 | 10869 | 6 | 2 | 62 | |
| GSE54994 | USP19 | 10869 | 0 | 36 | 17 | |
| GSE60625 | USP19 | 10869 | 5 | 0 | 6 | |
| GSE74703 | USP19 | 10869 | 0 | 14 | 22 | |
| GSE74704 | USP19 | 10869 | 0 | 12 | 8 | |
| TCGA | USP19 | 10869 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of USP19:
Generating mutation plots.
Highly correlated genes for USP19:
Showing top 20/425 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP19 | GPR37L1 | 0.776121 | 3 | 0 | 3 |
| USP19 | NPFF | 0.774488 | 3 | 0 | 3 |
| USP19 | PSKH1 | 0.769376 | 3 | 0 | 3 |
| USP19 | ATG14 | 0.754026 | 3 | 0 | 3 |
| USP19 | JPH2 | 0.743186 | 3 | 0 | 3 |
| USP19 | TADA2B | 0.740818 | 3 | 0 | 3 |
| USP19 | ZNF814 | 0.726295 | 3 | 0 | 3 |
| USP19 | KRTAP5-8 | 0.719089 | 3 | 0 | 3 |
| USP19 | GABPA | 0.718305 | 3 | 0 | 3 |
| USP19 | SLC4A5 | 0.715649 | 3 | 0 | 3 |
| USP19 | KDM2A | 0.714435 | 3 | 0 | 3 |
| USP19 | GPATCH1 | 0.711982 | 3 | 0 | 3 |
| USP19 | ZNF358 | 0.708516 | 4 | 0 | 3 |
| USP19 | DAG1 | 0.70598 | 3 | 0 | 3 |
| USP19 | CCDC97 | 0.703585 | 4 | 0 | 4 |
| USP19 | RFXAP | 0.700028 | 4 | 0 | 3 |
| USP19 | HIGD2A | 0.69387 | 4 | 0 | 4 |
| USP19 | SLC18A2 | 0.692962 | 3 | 0 | 3 |
| USP19 | SCAMP4 | 0.692128 | 3 | 0 | 3 |
| USP19 | PDK2 | 0.691208 | 3 | 0 | 3 |
For details and further investigation, click here
