RPL7A

 

Full name: ribosomal protein L7a Alias Symbol: SURF3|TRUP|L7A
Type: protein-coding gene Cytoband: 9q34.2
Entrez ID: 6130 HGNC ID: HGNC:10364 Ensembl Gene: ENSG00000148303 OMIM ID: 185640
Drug and gene relationship at DGIdb

 

Expression of RPL7A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 RPL7A 6130 9077 -0.2002 0.0070
GSE53624 RPL7A 6130 28350 -0.0795 0.2040
GSE97050 RPL7A 6130 A_23_P135084 -0.2312 0.4373
SRP007169 RPL7A 6130 RNAseq -0.8226 0.0660
SRP008496 RPL7A 6130 RNAseq -0.6731 0.0083
SRP064894 RPL7A 6130 RNAseq -0.3668 0.2056
SRP133303 RPL7A 6130 RNAseq -0.7455 0.0000
SRP159526 RPL7A 6130 RNAseq -0.5693 0.0205
SRP193095 RPL7A 6130 RNAseq -0.9350 0.0000
SRP219564 RPL7A 6130 RNAseq -0.4350 0.2386
TCGA RPL7A 6130 RNAseq -0.0159 0.7821

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by RPL7A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RPL7A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RPL7A 6130 5 7 18
GSE20123 RPL7A 6130 5 7 18
GSE43470 RPL7A 6130 4 7 32
GSE46452 RPL7A 6130 6 13 40
GSE47630 RPL7A 6130 4 15 21
GSE54993 RPL7A 6130 3 3 64
GSE54994 RPL7A 6130 12 9 32
GSE60625 RPL7A 6130 0 0 11
GSE74703 RPL7A 6130 4 5 27
GSE74704 RPL7A 6130 3 5 12
TCGA RPL7A 6130 28 26 42

Total number of gains: 74; Total number of losses: 97; Total Number of normals: 317.  

 

Somatic mutations of RPL7A:

 

Generating mutation plots.

 

Highly correlated genes for RPL7A:

 

Showing all 12 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RPL7AZBTB430.66173303
RPL7AEDF10.658168403
RPL7ARPL240.65173303
RPL7ASSNA10.64052403
RPL7ARPLP00.627805403
RPL7ARPL120.624138403
RPL7ARPL350.560956403
RPL7ARPS60.555873303
RPL7ARPL390.555667403
RPL7ARPS130.543242403
RPL7ARPS80.543178403
RPL7ARPS20.530512403

For details and further investigation, click here