| Full name: ribosomal protein L12 | Alias Symbol: L12 | ||
| Type: protein-coding gene | Cytoband: 9q33.3 | ||
| Entrez ID: 6136 | HGNC ID: HGNC:10302 | Ensembl Gene: ENSG00000197958 | OMIM ID: 180475 |
| Drug and gene relationship at DGIdb | |||
Expression of RPL12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL12 | 6136 | 200809_x_at | -0.0926 | 0.6287 | |
| GSE20347 | RPL12 | 6136 | 200809_x_at | -0.1114 | 0.2702 | |
| GSE23400 | RPL12 | 6136 | 200809_x_at | 0.0706 | 0.3397 | |
| GSE26886 | RPL12 | 6136 | 200809_x_at | 0.4954 | 0.0000 | |
| GSE29001 | RPL12 | 6136 | 200809_x_at | -0.1485 | 0.4266 | |
| GSE38129 | RPL12 | 6136 | 200809_x_at | 0.0744 | 0.3958 | |
| GSE45670 | RPL12 | 6136 | 200809_x_at | -0.2017 | 0.0902 | |
| GSE53622 | RPL12 | 6136 | 16705 | -0.0387 | 0.5981 | |
| GSE53624 | RPL12 | 6136 | 16705 | 0.3542 | 0.0000 | |
| GSE63941 | RPL12 | 6136 | 200809_x_at | 0.6861 | 0.0045 | |
| GSE77861 | RPL12 | 6136 | 200809_x_at | -0.0731 | 0.7603 | |
| GSE97050 | RPL12 | 6136 | A_23_P217068 | -0.1901 | 0.7229 | |
| SRP007169 | RPL12 | 6136 | RNAseq | -1.1094 | 0.0018 | |
| SRP008496 | RPL12 | 6136 | RNAseq | -0.9640 | 0.0000 | |
| SRP064894 | RPL12 | 6136 | RNAseq | -0.1884 | 0.5214 | |
| SRP133303 | RPL12 | 6136 | RNAseq | -0.4398 | 0.0044 | |
| SRP159526 | RPL12 | 6136 | RNAseq | -0.3995 | 0.0035 | |
| SRP193095 | RPL12 | 6136 | RNAseq | -0.8929 | 0.0000 | |
| SRP219564 | RPL12 | 6136 | RNAseq | -0.6168 | 0.0921 | |
| TCGA | RPL12 | 6136 | RNAseq | 0.1480 | 0.0524 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RPL12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL12 | 6136 | 6 | 9 | 15 | |
| GSE20123 | RPL12 | 6136 | 6 | 9 | 15 | |
| GSE43470 | RPL12 | 6136 | 5 | 6 | 32 | |
| GSE46452 | RPL12 | 6136 | 6 | 13 | 40 | |
| GSE47630 | RPL12 | 6136 | 3 | 16 | 21 | |
| GSE54993 | RPL12 | 6136 | 3 | 3 | 64 | |
| GSE54994 | RPL12 | 6136 | 11 | 8 | 34 | |
| GSE60625 | RPL12 | 6136 | 0 | 0 | 11 | |
| GSE74703 | RPL12 | 6136 | 5 | 4 | 27 | |
| GSE74704 | RPL12 | 6136 | 3 | 7 | 10 | |
| TCGA | RPL12 | 6136 | 27 | 25 | 44 |
Total number of gains: 75; Total number of losses: 100; Total Number of normals: 313.
Somatic mutations of RPL12:
Generating mutation plots.
Highly correlated genes for RPL12:
Showing top 20/215 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL12 | RPS2 | 0.759216 | 3 | 0 | 3 |
| RPL12 | EFNA1 | 0.726252 | 3 | 0 | 3 |
| RPL12 | GPS2 | 0.709639 | 4 | 0 | 4 |
| RPL12 | RAD23A | 0.705181 | 3 | 0 | 3 |
| RPL12 | TRAPPC1 | 0.704589 | 3 | 0 | 3 |
| RPL12 | C12orf45 | 0.700556 | 3 | 0 | 3 |
| RPL12 | RPL35 | 0.695182 | 12 | 0 | 11 |
| RPL12 | RPS18 | 0.692998 | 9 | 0 | 8 |
| RPL12 | RPS26 | 0.689676 | 3 | 0 | 3 |
| RPL12 | STAMBP | 0.681996 | 3 | 0 | 3 |
| RPL12 | STRBP | 0.671125 | 3 | 0 | 3 |
| RPL12 | ADAR | 0.670528 | 3 | 0 | 3 |
| RPL12 | KLHL23 | 0.662403 | 3 | 0 | 3 |
| RPL12 | RPL31 | 0.659577 | 12 | 0 | 10 |
| RPL12 | RPS3 | 0.656361 | 9 | 0 | 6 |
| RPL12 | RPL22 | 0.65602 | 4 | 0 | 3 |
| RPL12 | MARK1 | 0.652932 | 3 | 0 | 3 |
| RPL12 | IPO9 | 0.649348 | 3 | 0 | 3 |
| RPL12 | CDK2AP2 | 0.64761 | 3 | 0 | 3 |
| RPL12 | CMC4 | 0.645957 | 3 | 0 | 3 |
For details and further investigation, click here
