| Full name: ribosomal protein lateral stalk subunit P0 | Alias Symbol: PRLP0|P0|L10E|RPP0|LP0 | ||
| Type: protein-coding gene | Cytoband: 12q24.23 | ||
| Entrez ID: 6175 | HGNC ID: HGNC:10371 | Ensembl Gene: ENSG00000089157 | OMIM ID: 180510 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPLP0:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPLP0 | 6175 | 201033_x_at | -0.0001 | 0.9997 | |
| GSE20347 | RPLP0 | 6175 | 201033_x_at | -0.0812 | 0.3472 | |
| GSE23400 | RPLP0 | 6175 | 201033_x_at | -0.0850 | 0.0417 | |
| GSE26886 | RPLP0 | 6175 | 201033_x_at | -0.0741 | 0.5077 | |
| GSE29001 | RPLP0 | 6175 | 208856_x_at | -0.1889 | 0.4061 | |
| GSE38129 | RPLP0 | 6175 | 211720_x_at | 0.0462 | 0.5336 | |
| GSE45670 | RPLP0 | 6175 | 211720_x_at | -0.1560 | 0.0080 | |
| GSE53622 | RPLP0 | 6175 | 89007 | -0.2766 | 0.0001 | |
| GSE53624 | RPLP0 | 6175 | 76790 | -0.0918 | 0.1429 | |
| GSE63941 | RPLP0 | 6175 | 211720_x_at | 0.0620 | 0.6419 | |
| GSE77861 | RPLP0 | 6175 | 201033_x_at | -0.1246 | 0.4222 | |
| GSE97050 | RPLP0 | 6175 | A_23_P204472 | -0.3427 | 0.4042 | |
| SRP007169 | RPLP0 | 6175 | RNAseq | -1.6320 | 0.0000 | |
| SRP008496 | RPLP0 | 6175 | RNAseq | -1.4409 | 0.0000 | |
| SRP064894 | RPLP0 | 6175 | RNAseq | -0.4641 | 0.1167 | |
| SRP133303 | RPLP0 | 6175 | RNAseq | -0.6379 | 0.0000 | |
| SRP159526 | RPLP0 | 6175 | RNAseq | -0.6743 | 0.0034 | |
| SRP193095 | RPLP0 | 6175 | RNAseq | -0.9154 | 0.0000 | |
| SRP219564 | RPLP0 | 6175 | RNAseq | -0.5531 | 0.1399 | |
| TCGA | RPLP0 | 6175 | RNAseq | 0.0309 | 0.4736 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RPLP0 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPLP0:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPLP0 | 6175 | 6 | 2 | 22 | |
| GSE20123 | RPLP0 | 6175 | 6 | 2 | 22 | |
| GSE43470 | RPLP0 | 6175 | 2 | 2 | 39 | |
| GSE46452 | RPLP0 | 6175 | 9 | 1 | 49 | |
| GSE47630 | RPLP0 | 6175 | 9 | 3 | 28 | |
| GSE54993 | RPLP0 | 6175 | 0 | 5 | 65 | |
| GSE54994 | RPLP0 | 6175 | 7 | 6 | 40 | |
| GSE60625 | RPLP0 | 6175 | 0 | 0 | 11 | |
| GSE74703 | RPLP0 | 6175 | 2 | 1 | 33 | |
| GSE74704 | RPLP0 | 6175 | 3 | 2 | 15 | |
| TCGA | RPLP0 | 6175 | 20 | 11 | 65 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of RPLP0:
Generating mutation plots.
Highly correlated genes for RPLP0:
Showing top 20/482 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPLP0 | RPL18A | 0.740232 | 3 | 0 | 3 |
| RPLP0 | RPL6 | 0.692891 | 11 | 0 | 10 |
| RPLP0 | RPL3 | 0.686959 | 9 | 0 | 8 |
| RPLP0 | RPS18 | 0.679626 | 11 | 0 | 9 |
| RPLP0 | PSENEN | 0.677783 | 4 | 0 | 4 |
| RPLP0 | ZNF709 | 0.671347 | 3 | 0 | 3 |
| RPLP0 | UQCRFS1 | 0.670367 | 6 | 0 | 6 |
| RPLP0 | POLB | 0.667628 | 3 | 0 | 3 |
| RPLP0 | RPS3A | 0.666387 | 3 | 0 | 3 |
| RPLP0 | ARID1A | 0.665089 | 3 | 0 | 3 |
| RPLP0 | NDUFA9 | 0.66443 | 3 | 0 | 3 |
| RPLP0 | OOEP | 0.664151 | 3 | 0 | 3 |
| RPLP0 | YIF1A | 0.662445 | 3 | 0 | 3 |
| RPLP0 | RPS5 | 0.658575 | 13 | 0 | 11 |
| RPLP0 | RPL13A | 0.654726 | 4 | 0 | 3 |
| RPLP0 | RPLP1 | 0.653868 | 9 | 0 | 7 |
| RPLP0 | C2CD2 | 0.653547 | 3 | 0 | 3 |
| RPLP0 | TAF10 | 0.65254 | 3 | 0 | 3 |
| RPLP0 | BLOC1S2 | 0.651655 | 4 | 0 | 4 |
| RPLP0 | ARPC1A | 0.644606 | 6 | 0 | 5 |
For details and further investigation, click here
