| Full name: ribosomal protein L35 | Alias Symbol: L35 | ||
| Type: protein-coding gene | Cytoband: 9q33.3 | ||
| Entrez ID: 11224 | HGNC ID: HGNC:10344 | Ensembl Gene: ENSG00000136942 | OMIM ID: 618315 |
| Drug and gene relationship at DGIdb | |||
Expression of RPL35:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL35 | 11224 | 200002_at | -0.0922 | 0.6178 | |
| GSE20347 | RPL35 | 11224 | 200002_at | -0.1467 | 0.2609 | |
| GSE23400 | RPL35 | 11224 | 200002_at | 0.1045 | 0.1688 | |
| GSE26886 | RPL35 | 11224 | 200002_at | 0.2261 | 0.3955 | |
| GSE29001 | RPL35 | 11224 | 200002_at | -0.1562 | 0.6603 | |
| GSE38129 | RPL35 | 11224 | 200002_at | -0.0215 | 0.8366 | |
| GSE45670 | RPL35 | 11224 | 200002_at | -0.1232 | 0.2142 | |
| GSE53622 | RPL35 | 11224 | 45317 | 0.3130 | 0.0001 | |
| GSE53624 | RPL35 | 11224 | 45317 | 0.5489 | 0.0000 | |
| GSE63941 | RPL35 | 11224 | 200002_at | 0.8450 | 0.0002 | |
| GSE77861 | RPL35 | 11224 | 200002_at | -0.0594 | 0.7031 | |
| GSE97050 | RPL35 | 11224 | A_23_P112429 | 0.0309 | 0.9370 | |
| SRP007169 | RPL35 | 11224 | RNAseq | -0.7915 | 0.0184 | |
| SRP008496 | RPL35 | 11224 | RNAseq | -0.6717 | 0.0002 | |
| SRP064894 | RPL35 | 11224 | RNAseq | 0.2036 | 0.6141 | |
| SRP133303 | RPL35 | 11224 | RNAseq | -0.2666 | 0.1090 | |
| SRP159526 | RPL35 | 11224 | RNAseq | -0.5535 | 0.0028 | |
| SRP193095 | RPL35 | 11224 | RNAseq | -0.8738 | 0.0000 | |
| SRP219564 | RPL35 | 11224 | RNAseq | -0.4777 | 0.1515 | |
| TCGA | RPL35 | 11224 | RNAseq | 0.1489 | 0.0200 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPL35 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL35:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL35 | 11224 | 4 | 8 | 18 | |
| GSE20123 | RPL35 | 11224 | 4 | 8 | 18 | |
| GSE43470 | RPL35 | 11224 | 6 | 4 | 33 | |
| GSE46452 | RPL35 | 11224 | 6 | 13 | 40 | |
| GSE47630 | RPL35 | 11224 | 3 | 16 | 21 | |
| GSE54993 | RPL35 | 11224 | 3 | 3 | 64 | |
| GSE54994 | RPL35 | 11224 | 12 | 8 | 33 | |
| GSE60625 | RPL35 | 11224 | 0 | 0 | 11 | |
| GSE74703 | RPL35 | 11224 | 5 | 3 | 28 | |
| GSE74704 | RPL35 | 11224 | 2 | 6 | 12 | |
| TCGA | RPL35 | 11224 | 27 | 25 | 44 |
Total number of gains: 72; Total number of losses: 94; Total Number of normals: 322.
Somatic mutations of RPL35:
Generating mutation plots.
Highly correlated genes for RPL35:
Showing top 20/169 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL35 | RPL12 | 0.695182 | 12 | 0 | 11 |
| RPL35 | MACROD1 | 0.68872 | 3 | 0 | 3 |
| RPL35 | ZNF296 | 0.682593 | 3 | 0 | 3 |
| RPL35 | GSTO2 | 0.675317 | 3 | 0 | 3 |
| RPL35 | RPL41 | 0.647043 | 6 | 0 | 6 |
| RPL35 | RPL18 | 0.640894 | 8 | 0 | 7 |
| RPL35 | COMTD1 | 0.638793 | 3 | 0 | 3 |
| RPL35 | RPS29 | 0.6371 | 4 | 0 | 3 |
| RPL35 | KRT18 | 0.634308 | 5 | 0 | 4 |
| RPL35 | RPS15 | 0.628625 | 12 | 0 | 10 |
| RPL35 | TUBGCP2 | 0.627656 | 4 | 0 | 3 |
| RPL35 | RPL36 | 0.623793 | 11 | 0 | 9 |
| RPL35 | RPL31 | 0.621643 | 8 | 0 | 6 |
| RPL35 | HLA-G | 0.621274 | 4 | 0 | 3 |
| RPL35 | PPP1CA | 0.618819 | 6 | 0 | 6 |
| RPL35 | LSM4 | 0.618428 | 3 | 0 | 3 |
| RPL35 | RPS24 | 0.615052 | 8 | 0 | 7 |
| RPL35 | RPS5 | 0.612012 | 10 | 0 | 8 |
| RPL35 | DANCR | 0.606715 | 3 | 0 | 3 |
| RPL35 | SET | 0.605711 | 3 | 0 | 3 |
For details and further investigation, click here
