| Full name: small nuclear ribonucleoprotein polypeptide N | Alias Symbol: SMN|SM-D|HCERN3|SNRNP-N|SNURF-SNRPN|RT-LI | ||
| Type: protein-coding gene | Cytoband: 15q11.2 | ||
| Entrez ID: 6638 | HGNC ID: HGNC:11164 | Ensembl Gene: ENSG00000128739 | OMIM ID: 182279 |
| Drug and gene relationship at DGIdb | |||
Expression of SNRPN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNRPN | 6638 | 240204_at | 0.1026 | 0.6986 | |
| GSE26886 | SNRPN | 6638 | 240204_at | 0.0112 | 0.9161 | |
| GSE45670 | SNRPN | 6638 | 240204_at | -0.0152 | 0.8442 | |
| GSE63941 | SNRPN | 6638 | 240204_at | -0.1278 | 0.3946 | |
| GSE77861 | SNRPN | 6638 | 240204_at | -0.0052 | 0.9690 | |
| GSE97050 | SNRPN | 6638 | A_23_P77066 | -0.5887 | 0.1618 | |
| SRP064894 | SNRPN | 6638 | RNAseq | -0.6091 | 0.0631 | |
| SRP133303 | SNRPN | 6638 | RNAseq | -0.6115 | 0.1179 | |
| SRP159526 | SNRPN | 6638 | RNAseq | 0.0793 | 0.8887 | |
| SRP219564 | SNRPN | 6638 | RNAseq | -0.6354 | 0.3283 | |
| TCGA | SNRPN | 6638 | RNAseq | -0.5135 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNRPN expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SNRPN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNRPN | 6638 | 2 | 7 | 21 | |
| GSE20123 | SNRPN | 6638 | 2 | 7 | 21 | |
| GSE43470 | SNRPN | 6638 | 3 | 5 | 35 | |
| GSE46452 | SNRPN | 6638 | 3 | 7 | 49 | |
| GSE47630 | SNRPN | 6638 | 8 | 11 | 21 | |
| GSE54993 | SNRPN | 6638 | 4 | 6 | 60 | |
| GSE54994 | SNRPN | 6638 | 7 | 6 | 40 | |
| GSE60625 | SNRPN | 6638 | 4 | 3 | 4 | |
| GSE74703 | SNRPN | 6638 | 3 | 3 | 30 | |
| GSE74704 | SNRPN | 6638 | 1 | 5 | 14 | |
| TCGA | SNRPN | 6638 | 17 | 20 | 59 |
Total number of gains: 54; Total number of losses: 80; Total Number of normals: 354.
Somatic mutations of SNRPN:
Generating mutation plots.
Highly correlated genes for SNRPN:
Showing top 20/50 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNRPN | KEAP1 | 0.775273 | 3 | 0 | 3 |
| SNRPN | PCID2 | 0.763172 | 3 | 0 | 3 |
| SNRPN | DNAJC21 | 0.760107 | 3 | 0 | 3 |
| SNRPN | ZFX | 0.743047 | 3 | 0 | 3 |
| SNRPN | PMF1 | 0.73214 | 3 | 0 | 3 |
| SNRPN | ZNF35 | 0.730418 | 3 | 0 | 3 |
| SNRPN | QTRT1 | 0.723411 | 3 | 0 | 3 |
| SNRPN | C16orf46 | 0.719813 | 3 | 0 | 3 |
| SNRPN | FICD | 0.719366 | 3 | 0 | 3 |
| SNRPN | LMBRD2 | 0.706369 | 3 | 0 | 3 |
| SNRPN | MRPS33 | 0.703851 | 3 | 0 | 3 |
| SNRPN | TRAPPC8 | 0.702001 | 3 | 0 | 3 |
| SNRPN | NAA30 | 0.693938 | 3 | 0 | 3 |
| SNRPN | NDUFA13 | 0.691331 | 3 | 0 | 3 |
| SNRPN | UNC5CL | 0.683979 | 3 | 0 | 3 |
| SNRPN | ZXDA | 0.680294 | 4 | 0 | 3 |
| SNRPN | CXorf40B | 0.677927 | 3 | 0 | 3 |
| SNRPN | MAD2L2 | 0.677676 | 3 | 0 | 3 |
| SNRPN | ZNF318 | 0.676039 | 3 | 0 | 3 |
| SNRPN | ZNF354C | 0.675165 | 3 | 0 | 3 |
For details and further investigation, click here
