| Full name: LMBR1 domain containing 2 | Alias Symbol: DKFZp434H2226 | ||
| Type: protein-coding gene | Cytoband: 5p13.2 | ||
| Entrez ID: 92255 | HGNC ID: HGNC:25287 | Ensembl Gene: ENSG00000164187 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LMBRD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMBRD2 | 92255 | 226779_at | -0.0676 | 0.8800 | |
| GSE26886 | LMBRD2 | 92255 | 226779_at | -0.4927 | 0.2237 | |
| GSE45670 | LMBRD2 | 92255 | 226779_at | 0.0384 | 0.8691 | |
| GSE53622 | LMBRD2 | 92255 | 10081 | -0.2969 | 0.0005 | |
| GSE53624 | LMBRD2 | 92255 | 32566 | -0.2866 | 0.0000 | |
| GSE63941 | LMBRD2 | 92255 | 226779_at | -0.5660 | 0.4230 | |
| GSE77861 | LMBRD2 | 92255 | 226779_at | -0.0489 | 0.9106 | |
| GSE97050 | LMBRD2 | 92255 | A_23_P327698 | 0.0408 | 0.8733 | |
| SRP007169 | LMBRD2 | 92255 | RNAseq | -0.4259 | 0.1403 | |
| SRP008496 | LMBRD2 | 92255 | RNAseq | -0.2378 | 0.3485 | |
| SRP064894 | LMBRD2 | 92255 | RNAseq | -0.4372 | 0.1019 | |
| SRP133303 | LMBRD2 | 92255 | RNAseq | 0.0113 | 0.9362 | |
| SRP159526 | LMBRD2 | 92255 | RNAseq | -0.0447 | 0.9191 | |
| SRP193095 | LMBRD2 | 92255 | RNAseq | -0.6046 | 0.0000 | |
| SRP219564 | LMBRD2 | 92255 | RNAseq | -0.5604 | 0.0890 | |
| TCGA | LMBRD2 | 92255 | RNAseq | -0.2738 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LMBRD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMBRD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMBRD2 | 92255 | 10 | 0 | 20 | |
| GSE20123 | LMBRD2 | 92255 | 10 | 0 | 20 | |
| GSE43470 | LMBRD2 | 92255 | 17 | 0 | 26 | |
| GSE46452 | LMBRD2 | 92255 | 5 | 22 | 32 | |
| GSE47630 | LMBRD2 | 92255 | 6 | 12 | 22 | |
| GSE54993 | LMBRD2 | 92255 | 5 | 4 | 61 | |
| GSE54994 | LMBRD2 | 92255 | 26 | 2 | 25 | |
| GSE60625 | LMBRD2 | 92255 | 0 | 0 | 11 | |
| GSE74703 | LMBRD2 | 92255 | 13 | 0 | 23 | |
| GSE74704 | LMBRD2 | 92255 | 9 | 0 | 11 | |
| TCGA | LMBRD2 | 92255 | 52 | 6 | 38 |
Total number of gains: 153; Total number of losses: 46; Total Number of normals: 289.
Somatic mutations of LMBRD2:
Generating mutation plots.
Highly correlated genes for LMBRD2:
Showing top 20/222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMBRD2 | RRAGB | 0.851618 | 3 | 0 | 3 |
| LMBRD2 | DHX40 | 0.809923 | 3 | 0 | 3 |
| LMBRD2 | ZNF564 | 0.802669 | 3 | 0 | 3 |
| LMBRD2 | NHS | 0.7874 | 3 | 0 | 3 |
| LMBRD2 | SCAF8 | 0.784202 | 3 | 0 | 3 |
| LMBRD2 | TXNDC16 | 0.777089 | 3 | 0 | 3 |
| LMBRD2 | SON | 0.766341 | 3 | 0 | 3 |
| LMBRD2 | RHBDD1 | 0.7606 | 3 | 0 | 3 |
| LMBRD2 | ELAC1 | 0.757292 | 3 | 0 | 3 |
| LMBRD2 | FGFR1OP2 | 0.754397 | 3 | 0 | 3 |
| LMBRD2 | GABPA | 0.752876 | 3 | 0 | 3 |
| LMBRD2 | ASH2L | 0.751302 | 3 | 0 | 3 |
| LMBRD2 | ZNF317 | 0.751224 | 3 | 0 | 3 |
| LMBRD2 | GLUD1 | 0.750322 | 3 | 0 | 3 |
| LMBRD2 | FBXO11 | 0.748903 | 3 | 0 | 3 |
| LMBRD2 | UBR2 | 0.745398 | 4 | 0 | 3 |
| LMBRD2 | ALG6 | 0.7448 | 3 | 0 | 3 |
| LMBRD2 | SPIN4 | 0.735913 | 3 | 0 | 3 |
| LMBRD2 | BIVM | 0.735228 | 3 | 0 | 3 |
| LMBRD2 | C17orf80 | 0.734089 | 3 | 0 | 3 |
For details and further investigation, click here
