| Full name: mitochondrial ribosomal protein S33 | Alias Symbol: CGI-139 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 51650 | HGNC ID: HGNC:16634 | Ensembl Gene: ENSG00000090263 | OMIM ID: 611993 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPS33:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS33 | 51650 | 218654_s_at | -0.1237 | 0.8075 | |
| GSE20347 | MRPS33 | 51650 | 218654_s_at | 0.2471 | 0.1510 | |
| GSE23400 | MRPS33 | 51650 | 218654_s_at | 0.2897 | 0.0000 | |
| GSE26886 | MRPS33 | 51650 | 218654_s_at | -0.4967 | 0.1060 | |
| GSE29001 | MRPS33 | 51650 | 218654_s_at | 0.1181 | 0.6333 | |
| GSE38129 | MRPS33 | 51650 | 218654_s_at | 0.3624 | 0.0050 | |
| GSE45670 | MRPS33 | 51650 | 218654_s_at | 0.2132 | 0.2764 | |
| GSE53622 | MRPS33 | 51650 | 122851 | 0.1186 | 0.1316 | |
| GSE53624 | MRPS33 | 51650 | 122851 | 0.2954 | 0.0000 | |
| GSE63941 | MRPS33 | 51650 | 218654_s_at | 0.5508 | 0.0655 | |
| GSE77861 | MRPS33 | 51650 | 218654_s_at | 0.3372 | 0.0930 | |
| GSE97050 | MRPS33 | 51650 | A_23_P157352 | 0.1869 | 0.4596 | |
| SRP007169 | MRPS33 | 51650 | RNAseq | 0.2884 | 0.3684 | |
| SRP008496 | MRPS33 | 51650 | RNAseq | 0.5059 | 0.0232 | |
| SRP064894 | MRPS33 | 51650 | RNAseq | 0.1844 | 0.4309 | |
| SRP133303 | MRPS33 | 51650 | RNAseq | 0.2506 | 0.1173 | |
| SRP159526 | MRPS33 | 51650 | RNAseq | 0.0032 | 0.9919 | |
| SRP193095 | MRPS33 | 51650 | RNAseq | -0.4105 | 0.0019 | |
| SRP219564 | MRPS33 | 51650 | RNAseq | -0.4905 | 0.0666 | |
| TCGA | MRPS33 | 51650 | RNAseq | 0.0723 | 0.3226 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPS33 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS33:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS33 | 51650 | 5 | 2 | 23 | |
| GSE20123 | MRPS33 | 51650 | 5 | 2 | 23 | |
| GSE43470 | MRPS33 | 51650 | 2 | 4 | 37 | |
| GSE46452 | MRPS33 | 51650 | 7 | 2 | 50 | |
| GSE47630 | MRPS33 | 51650 | 7 | 4 | 29 | |
| GSE54993 | MRPS33 | 51650 | 3 | 5 | 62 | |
| GSE54994 | MRPS33 | 51650 | 5 | 8 | 40 | |
| GSE60625 | MRPS33 | 51650 | 0 | 0 | 11 | |
| GSE74703 | MRPS33 | 51650 | 2 | 4 | 30 | |
| GSE74704 | MRPS33 | 51650 | 1 | 2 | 17 | |
| TCGA | MRPS33 | 51650 | 27 | 23 | 46 |
Total number of gains: 64; Total number of losses: 56; Total Number of normals: 368.
Somatic mutations of MRPS33:
Generating mutation plots.
Highly correlated genes for MRPS33:
Showing top 20/446 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS33 | CSRNP2 | 0.752194 | 3 | 0 | 3 |
| MRPS33 | DLG3 | 0.745385 | 3 | 0 | 3 |
| MRPS33 | RPS6KA3 | 0.738088 | 5 | 0 | 4 |
| MRPS33 | GPD2 | 0.717546 | 3 | 0 | 3 |
| MRPS33 | FAM98C | 0.715097 | 3 | 0 | 3 |
| MRPS33 | LUC7L2 | 0.713553 | 5 | 0 | 5 |
| MRPS33 | RBM34 | 0.712342 | 3 | 0 | 3 |
| MRPS33 | SPPL2A | 0.71211 | 3 | 0 | 3 |
| MRPS33 | GSTK1 | 0.709893 | 4 | 0 | 3 |
| MRPS33 | RNF125 | 0.708605 | 3 | 0 | 3 |
| MRPS33 | ADO | 0.708565 | 3 | 0 | 3 |
| MRPS33 | DNAJB6 | 0.706209 | 3 | 0 | 3 |
| MRPS33 | BAG1 | 0.704089 | 3 | 0 | 3 |
| MRPS33 | SNRPN | 0.703851 | 3 | 0 | 3 |
| MRPS33 | HCCS | 0.702042 | 4 | 0 | 3 |
| MRPS33 | ACP6 | 0.696635 | 3 | 0 | 3 |
| MRPS33 | ZNF681 | 0.695119 | 3 | 0 | 3 |
| MRPS33 | TMEM205 | 0.692431 | 4 | 0 | 3 |
| MRPS33 | SENP8 | 0.692426 | 4 | 0 | 4 |
| MRPS33 | C1orf115 | 0.687681 | 3 | 0 | 3 |
For details and further investigation, click here
