| Full name: unc-5 family C-terminal like | Alias Symbol: MGC34763|ZUD | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 222643 | HGNC ID: HGNC:21203 | Ensembl Gene: ENSG00000124602 | OMIM ID: 617464 |
| Drug and gene relationship at DGIdb | |||
Expression of UNC5CL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UNC5CL | 222643 | 231008_at | 0.0698 | 0.8203 | |
| GSE26886 | UNC5CL | 222643 | 231008_at | 0.0754 | 0.6082 | |
| GSE45670 | UNC5CL | 222643 | 231008_at | 0.0891 | 0.6792 | |
| GSE53622 | UNC5CL | 222643 | 83743 | -0.3748 | 0.0002 | |
| GSE53624 | UNC5CL | 222643 | 83743 | -0.6763 | 0.0000 | |
| GSE63941 | UNC5CL | 222643 | 231008_at | 0.3276 | 0.3039 | |
| GSE77861 | UNC5CL | 222643 | 231008_at | -0.0494 | 0.6689 | |
| GSE97050 | UNC5CL | 222643 | A_33_P3374299 | -0.0725 | 0.8138 | |
| SRP064894 | UNC5CL | 222643 | RNAseq | 0.5889 | 0.0975 | |
| SRP133303 | UNC5CL | 222643 | RNAseq | -0.5419 | 0.0323 | |
| SRP159526 | UNC5CL | 222643 | RNAseq | 1.1257 | 0.0810 | |
| TCGA | UNC5CL | 222643 | RNAseq | -1.2964 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UNC5CL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UNC5CL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UNC5CL | 222643 | 3 | 3 | 24 | |
| GSE20123 | UNC5CL | 222643 | 3 | 3 | 24 | |
| GSE43470 | UNC5CL | 222643 | 6 | 0 | 37 | |
| GSE46452 | UNC5CL | 222643 | 2 | 9 | 48 | |
| GSE47630 | UNC5CL | 222643 | 8 | 4 | 28 | |
| GSE54993 | UNC5CL | 222643 | 3 | 2 | 65 | |
| GSE54994 | UNC5CL | 222643 | 11 | 4 | 38 | |
| GSE60625 | UNC5CL | 222643 | 0 | 1 | 10 | |
| GSE74703 | UNC5CL | 222643 | 6 | 0 | 30 | |
| GSE74704 | UNC5CL | 222643 | 1 | 3 | 16 | |
| TCGA | UNC5CL | 222643 | 19 | 13 | 64 |
Total number of gains: 62; Total number of losses: 42; Total Number of normals: 384.
Somatic mutations of UNC5CL:
Generating mutation plots.
Highly correlated genes for UNC5CL:
Showing top 20/89 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UNC5CL | CMTM6 | 0.83038 | 3 | 0 | 3 |
| UNC5CL | SRPK1 | 0.814189 | 3 | 0 | 3 |
| UNC5CL | UBA3 | 0.789419 | 3 | 0 | 3 |
| UNC5CL | RPP38 | 0.788453 | 3 | 0 | 3 |
| UNC5CL | SPATA5L1 | 0.776215 | 3 | 0 | 3 |
| UNC5CL | ZNF394 | 0.771641 | 3 | 0 | 3 |
| UNC5CL | C6orf120 | 0.766448 | 3 | 0 | 3 |
| UNC5CL | ZNF101 | 0.76307 | 3 | 0 | 3 |
| UNC5CL | PARG | 0.759767 | 3 | 0 | 3 |
| UNC5CL | CNOT10 | 0.75716 | 3 | 0 | 3 |
| UNC5CL | MRPS18C | 0.755956 | 3 | 0 | 3 |
| UNC5CL | MTCH2 | 0.751475 | 3 | 0 | 3 |
| UNC5CL | TCF19 | 0.74918 | 3 | 0 | 3 |
| UNC5CL | TRAPPC8 | 0.746328 | 3 | 0 | 3 |
| UNC5CL | SRP9 | 0.738234 | 3 | 0 | 3 |
| UNC5CL | SYPL1 | 0.735336 | 3 | 0 | 3 |
| UNC5CL | FAN1 | 0.725019 | 3 | 0 | 3 |
| UNC5CL | TET2 | 0.723773 | 4 | 0 | 4 |
| UNC5CL | ZNF273 | 0.721956 | 3 | 0 | 3 |
| UNC5CL | MRPL42 | 0.719542 | 3 | 0 | 3 |
For details and further investigation, click here
