| Full name: DnaJ heat shock protein family (Hsp40) member C21 | Alias Symbol: GS3|DNAJA5|JJJ1 | ||
| Type: protein-coding gene | Cytoband: 5p13.2 | ||
| Entrez ID: 134218 | HGNC ID: HGNC:27030 | Ensembl Gene: ENSG00000168724 | OMIM ID: 617048 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJC21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC21 | 134218 | 238337_s_at | -0.0869 | 0.7971 | |
| GSE26886 | DNAJC21 | 134218 | 235032_at | 0.3141 | 0.0772 | |
| GSE45670 | DNAJC21 | 134218 | 238337_s_at | 0.0444 | 0.8041 | |
| GSE53622 | DNAJC21 | 134218 | 54867 | -0.8429 | 0.0000 | |
| GSE53624 | DNAJC21 | 134218 | 54867 | -0.7671 | 0.0000 | |
| GSE63941 | DNAJC21 | 134218 | 238337_s_at | -0.1113 | 0.7645 | |
| GSE77861 | DNAJC21 | 134218 | 235032_at | -0.2119 | 0.4259 | |
| GSE97050 | DNAJC21 | 134218 | A_33_P3310533 | -0.0313 | 0.9146 | |
| SRP007169 | DNAJC21 | 134218 | RNAseq | 0.9359 | 0.0457 | |
| SRP008496 | DNAJC21 | 134218 | RNAseq | 0.8825 | 0.0126 | |
| SRP064894 | DNAJC21 | 134218 | RNAseq | -0.4052 | 0.0082 | |
| SRP133303 | DNAJC21 | 134218 | RNAseq | -0.0616 | 0.6073 | |
| SRP159526 | DNAJC21 | 134218 | RNAseq | 0.0428 | 0.8899 | |
| SRP193095 | DNAJC21 | 134218 | RNAseq | -0.4302 | 0.0002 | |
| SRP219564 | DNAJC21 | 134218 | RNAseq | -0.6315 | 0.0315 | |
| TCGA | DNAJC21 | 134218 | RNAseq | -0.0072 | 0.8813 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNAJC21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC21 | 134218 | 10 | 0 | 20 | |
| GSE20123 | DNAJC21 | 134218 | 10 | 0 | 20 | |
| GSE43470 | DNAJC21 | 134218 | 18 | 0 | 25 | |
| GSE46452 | DNAJC21 | 134218 | 6 | 21 | 32 | |
| GSE47630 | DNAJC21 | 134218 | 6 | 12 | 22 | |
| GSE54993 | DNAJC21 | 134218 | 5 | 4 | 61 | |
| GSE54994 | DNAJC21 | 134218 | 26 | 2 | 25 | |
| GSE60625 | DNAJC21 | 134218 | 0 | 0 | 11 | |
| GSE74703 | DNAJC21 | 134218 | 14 | 0 | 22 | |
| GSE74704 | DNAJC21 | 134218 | 9 | 0 | 11 | |
| TCGA | DNAJC21 | 134218 | 52 | 6 | 38 |
Total number of gains: 156; Total number of losses: 45; Total Number of normals: 287.
Somatic mutations of DNAJC21:
Generating mutation plots.
Highly correlated genes for DNAJC21:
Showing top 20/263 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC21 | SMARCC2 | 0.763841 | 3 | 0 | 3 |
| DNAJC21 | SNRPN | 0.760107 | 3 | 0 | 3 |
| DNAJC21 | UBE2L3 | 0.756325 | 4 | 0 | 4 |
| DNAJC21 | CCNB3 | 0.748156 | 3 | 0 | 3 |
| DNAJC21 | BUD31 | 0.746204 | 3 | 0 | 3 |
| DNAJC21 | ACSL3 | 0.736486 | 3 | 0 | 3 |
| DNAJC21 | BAG1 | 0.723834 | 3 | 0 | 3 |
| DNAJC21 | YIPF2 | 0.717991 | 3 | 0 | 3 |
| DNAJC21 | TCF7L2 | 0.717933 | 3 | 0 | 3 |
| DNAJC21 | HNRNPUL2 | 0.715728 | 3 | 0 | 3 |
| DNAJC21 | IGIP | 0.715661 | 3 | 0 | 3 |
| DNAJC21 | PAIP1 | 0.715346 | 4 | 0 | 4 |
| DNAJC21 | TMEM168 | 0.714373 | 3 | 0 | 3 |
| DNAJC21 | PACRGL | 0.71286 | 3 | 0 | 3 |
| DNAJC21 | RBBP6 | 0.710981 | 3 | 0 | 3 |
| DNAJC21 | PALM | 0.707651 | 3 | 0 | 3 |
| DNAJC21 | ZNF790 | 0.706577 | 3 | 0 | 3 |
| DNAJC21 | TSPYL1 | 0.706443 | 3 | 0 | 3 |
| DNAJC21 | TADA2B | 0.705755 | 3 | 0 | 3 |
| DNAJC21 | UFL1 | 0.701778 | 3 | 0 | 3 |
For details and further investigation, click here
