| Full name: polyamine modulated factor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q22 | ||
| Entrez ID: 11243 | HGNC ID: HGNC:9112 | Ensembl Gene: ENSG00000160783 | OMIM ID: 609176 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PMF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PMF1 | 11243 | 202337_at | 0.0074 | 0.9839 | |
| GSE20347 | PMF1 | 11243 | 202337_at | -0.0371 | 0.7429 | |
| GSE23400 | PMF1 | 11243 | 202337_at | 0.0419 | 0.3593 | |
| GSE26886 | PMF1 | 11243 | 202337_at | 0.0079 | 0.9721 | |
| GSE29001 | PMF1 | 11243 | 202337_at | 0.0793 | 0.6994 | |
| GSE38129 | PMF1 | 11243 | 202337_at | 0.0947 | 0.3119 | |
| GSE45670 | PMF1 | 11243 | 202337_at | 0.0305 | 0.6729 | |
| GSE53622 | PMF1 | 11243 | 67468 | 0.1867 | 0.0005 | |
| GSE53624 | PMF1 | 11243 | 67468 | 0.1421 | 0.0939 | |
| GSE63941 | PMF1 | 11243 | 202337_at | 1.9756 | 0.0002 | |
| GSE77861 | PMF1 | 11243 | 202337_at | 0.0939 | 0.6729 | |
| GSE97050 | PMF1 | 11243 | A_23_P635 | 0.1786 | 0.4148 | |
| SRP007169 | PMF1 | 11243 | RNAseq | -0.8057 | 0.0212 | |
| SRP008496 | PMF1 | 11243 | RNAseq | -0.2989 | 0.1919 | |
| SRP064894 | PMF1 | 11243 | RNAseq | 0.4086 | 0.1265 | |
| SRP133303 | PMF1 | 11243 | RNAseq | 0.0753 | 0.6616 | |
| SRP159526 | PMF1 | 11243 | RNAseq | 0.3784 | 0.1464 | |
| SRP193095 | PMF1 | 11243 | RNAseq | 0.0533 | 0.6728 | |
| SRP219564 | PMF1 | 11243 | RNAseq | 0.1933 | 0.4814 | |
| TCGA | PMF1 | 11243 | RNAseq | 0.0749 | 0.1677 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PMF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PMF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PMF1 | 11243 | 13 | 0 | 17 | |
| GSE20123 | PMF1 | 11243 | 13 | 0 | 17 | |
| GSE43470 | PMF1 | 11243 | 7 | 2 | 34 | |
| GSE46452 | PMF1 | 11243 | 2 | 1 | 56 | |
| GSE47630 | PMF1 | 11243 | 14 | 0 | 26 | |
| GSE54993 | PMF1 | 11243 | 0 | 5 | 65 | |
| GSE54994 | PMF1 | 11243 | 16 | 0 | 37 | |
| GSE60625 | PMF1 | 11243 | 0 | 0 | 11 | |
| GSE74703 | PMF1 | 11243 | 7 | 2 | 27 | |
| GSE74704 | PMF1 | 11243 | 6 | 0 | 14 | |
| TCGA | PMF1 | 11243 | 38 | 2 | 56 |
Total number of gains: 116; Total number of losses: 12; Total Number of normals: 360.
Somatic mutations of PMF1:
Generating mutation plots.
Highly correlated genes for PMF1:
Showing top 20/606 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PMF1 | PA2G4 | 0.779836 | 3 | 0 | 3 |
| PMF1 | NUB1 | 0.767889 | 3 | 0 | 3 |
| PMF1 | ZNF317 | 0.76257 | 3 | 0 | 3 |
| PMF1 | FKBP8 | 0.761846 | 3 | 0 | 3 |
| PMF1 | ZNF766 | 0.751312 | 3 | 0 | 3 |
| PMF1 | CNOT10 | 0.74797 | 3 | 0 | 3 |
| PMF1 | C11orf80 | 0.746499 | 3 | 0 | 3 |
| PMF1 | ARID2 | 0.746266 | 3 | 0 | 3 |
| PMF1 | RPUSD3 | 0.740658 | 3 | 0 | 3 |
| PMF1 | ZNF558 | 0.733793 | 3 | 0 | 3 |
| PMF1 | DDX18 | 0.73253 | 3 | 0 | 3 |
| PMF1 | SNRPN | 0.73214 | 3 | 0 | 3 |
| PMF1 | RHOG | 0.72901 | 3 | 0 | 3 |
| PMF1 | FAM76B | 0.728247 | 3 | 0 | 3 |
| PMF1 | INO80B | 0.727906 | 3 | 0 | 3 |
| PMF1 | NOTCH3 | 0.725554 | 4 | 0 | 4 |
| PMF1 | IRF2BP1 | 0.721609 | 5 | 0 | 5 |
| PMF1 | HIC2 | 0.72046 | 3 | 0 | 3 |
| PMF1 | FBXO21 | 0.719679 | 3 | 0 | 3 |
| PMF1 | VRK3 | 0.716607 | 5 | 0 | 5 |
For details and further investigation, click here
