| Full name: synaptonemal complex protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q23.2 | ||
| Entrez ID: 50511 | HGNC ID: HGNC:18130 | Ensembl Gene: ENSG00000139351 | OMIM ID: 604759 |
| Drug and gene relationship at DGIdb | |||
Expression of SYCP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYCP3 | 50511 | 1553599_a_at | -0.1060 | 0.7236 | |
| GSE26886 | SYCP3 | 50511 | 1553599_a_at | 0.0613 | 0.6550 | |
| GSE45670 | SYCP3 | 50511 | 1553599_a_at | -0.0986 | 0.4500 | |
| GSE53622 | SYCP3 | 50511 | 58885 | -0.3745 | 0.0005 | |
| GSE53624 | SYCP3 | 50511 | 58885 | -0.5553 | 0.0000 | |
| GSE63941 | SYCP3 | 50511 | 1553599_a_at | -0.0044 | 0.9815 | |
| GSE77861 | SYCP3 | 50511 | 1553599_a_at | 0.0128 | 0.8784 | |
| GSE97050 | SYCP3 | 50511 | A_23_P76374 | -0.4296 | 0.1897 | |
| SRP064894 | SYCP3 | 50511 | RNAseq | -0.4923 | 0.0758 | |
| SRP133303 | SYCP3 | 50511 | RNAseq | -1.0217 | 0.0323 | |
| SRP193095 | SYCP3 | 50511 | RNAseq | -0.5252 | 0.0752 | |
| SRP219564 | SYCP3 | 50511 | RNAseq | -0.7795 | 0.1095 | |
| TCGA | SYCP3 | 50511 | RNAseq | -2.1166 | 0.1425 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SYCP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYCP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYCP3 | 50511 | 2 | 2 | 26 | |
| GSE20123 | SYCP3 | 50511 | 2 | 2 | 26 | |
| GSE43470 | SYCP3 | 50511 | 2 | 0 | 41 | |
| GSE46452 | SYCP3 | 50511 | 9 | 1 | 49 | |
| GSE47630 | SYCP3 | 50511 | 9 | 1 | 30 | |
| GSE54993 | SYCP3 | 50511 | 0 | 5 | 65 | |
| GSE54994 | SYCP3 | 50511 | 4 | 2 | 47 | |
| GSE60625 | SYCP3 | 50511 | 0 | 0 | 11 | |
| GSE74703 | SYCP3 | 50511 | 2 | 0 | 34 | |
| GSE74704 | SYCP3 | 50511 | 1 | 2 | 17 | |
| TCGA | SYCP3 | 50511 | 18 | 10 | 68 |
Total number of gains: 49; Total number of losses: 25; Total Number of normals: 414.
Somatic mutations of SYCP3:
Generating mutation plots.
Highly correlated genes for SYCP3:
Showing all 14 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYCP3 | CXorf38 | 0.67129 | 3 | 0 | 3 |
| SYCP3 | TTC21A | 0.669853 | 3 | 0 | 3 |
| SYCP3 | ZNF302 | 0.65003 | 4 | 0 | 4 |
| SYCP3 | HSPA12B | 0.649022 | 3 | 0 | 3 |
| SYCP3 | RWDD3 | 0.647444 | 4 | 0 | 3 |
| SYCP3 | CYP4Z1 | 0.642116 | 4 | 0 | 3 |
| SYCP3 | MBP | 0.627804 | 3 | 0 | 3 |
| SYCP3 | PARD6A | 0.627414 | 3 | 0 | 3 |
| SYCP3 | CDH10 | 0.604353 | 4 | 0 | 3 |
| SYCP3 | NR2E1 | 0.585072 | 4 | 0 | 3 |
| SYCP3 | IKBKB | 0.538998 | 4 | 0 | 3 |
| SYCP3 | ZNF226 | 0.533369 | 5 | 0 | 3 |
| SYCP3 | SKAP1 | 0.525248 | 5 | 0 | 3 |
| SYCP3 | LYPD4 | 0.509897 | 5 | 0 | 3 |
For details and further investigation, click here
