| Full name: tetratricopeptide repeat domain 21A | Alias Symbol: STI2|IFT139A | ||
| Type: protein-coding gene | Cytoband: 3p22.2 | ||
| Entrez ID: 199223 | HGNC ID: HGNC:30761 | Ensembl Gene: ENSG00000168026 | OMIM ID: 611430 |
| Drug and gene relationship at DGIdb | |||
Expression of TTC21A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC21A | 199223 | 230997_at | -0.1483 | 0.7749 | |
| GSE26886 | TTC21A | 199223 | 230997_at | -0.5209 | 0.0114 | |
| GSE45670 | TTC21A | 199223 | 230997_at | -0.1423 | 0.4147 | |
| GSE53622 | TTC21A | 199223 | 18326 | -0.1941 | 0.0055 | |
| GSE53624 | TTC21A | 199223 | 18326 | -0.4334 | 0.0000 | |
| GSE63941 | TTC21A | 199223 | 230997_at | -0.2114 | 0.1998 | |
| GSE77861 | TTC21A | 199223 | 232308_at | -0.1494 | 0.2003 | |
| GSE97050 | TTC21A | 199223 | A_23_P428248 | -0.2443 | 0.3506 | |
| SRP064894 | TTC21A | 199223 | RNAseq | -0.4516 | 0.0646 | |
| SRP133303 | TTC21A | 199223 | RNAseq | -0.8985 | 0.0012 | |
| SRP159526 | TTC21A | 199223 | RNAseq | -0.8170 | 0.0674 | |
| SRP193095 | TTC21A | 199223 | RNAseq | -0.5851 | 0.0066 | |
| SRP219564 | TTC21A | 199223 | RNAseq | -0.5331 | 0.1172 | |
| TCGA | TTC21A | 199223 | RNAseq | -0.5744 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTC21A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC21A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC21A | 199223 | 0 | 19 | 11 | |
| GSE20123 | TTC21A | 199223 | 0 | 19 | 11 | |
| GSE43470 | TTC21A | 199223 | 0 | 20 | 23 | |
| GSE46452 | TTC21A | 199223 | 2 | 17 | 40 | |
| GSE47630 | TTC21A | 199223 | 1 | 25 | 14 | |
| GSE54993 | TTC21A | 199223 | 7 | 2 | 61 | |
| GSE54994 | TTC21A | 199223 | 1 | 33 | 19 | |
| GSE60625 | TTC21A | 199223 | 5 | 0 | 6 | |
| GSE74703 | TTC21A | 199223 | 0 | 16 | 20 | |
| GSE74704 | TTC21A | 199223 | 0 | 13 | 7 | |
| TCGA | TTC21A | 199223 | 2 | 70 | 24 |
Total number of gains: 18; Total number of losses: 234; Total Number of normals: 236.
Somatic mutations of TTC21A:
Generating mutation plots.
Highly correlated genes for TTC21A:
Showing top 20/220 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC21A | INSC | 0.834354 | 3 | 0 | 3 |
| TTC21A | SLC22A12 | 0.832839 | 3 | 0 | 3 |
| TTC21A | GDF7 | 0.822318 | 3 | 0 | 3 |
| TTC21A | PRSS38 | 0.812623 | 3 | 0 | 3 |
| TTC21A | OTOG | 0.810622 | 3 | 0 | 3 |
| TTC21A | YY2 | 0.806454 | 3 | 0 | 3 |
| TTC21A | KCNJ13 | 0.798009 | 3 | 0 | 3 |
| TTC21A | FOXA3 | 0.783746 | 3 | 0 | 3 |
| TTC21A | BTNL9 | 0.783678 | 3 | 0 | 3 |
| TTC21A | OR1F1 | 0.775168 | 3 | 0 | 3 |
| TTC21A | MYOD1 | 0.775023 | 3 | 0 | 3 |
| TTC21A | OR2B11 | 0.774287 | 3 | 0 | 3 |
| TTC21A | PAX2 | 0.763146 | 3 | 0 | 3 |
| TTC21A | NOBOX | 0.760529 | 3 | 0 | 3 |
| TTC21A | CPNE9 | 0.753905 | 3 | 0 | 3 |
| TTC21A | DDC | 0.751359 | 3 | 0 | 3 |
| TTC21A | OR13G1 | 0.749914 | 3 | 0 | 3 |
| TTC21A | PDE6C | 0.749502 | 3 | 0 | 3 |
| TTC21A | SIM1 | 0.746613 | 3 | 0 | 3 |
| TTC21A | ENTPD8 | 0.74391 | 3 | 0 | 3 |
For details and further investigation, click here
