| Full name: LY6/PLAUR domain containing 4 | Alias Symbol: MGC42718 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 147719 | HGNC ID: HGNC:28659 | Ensembl Gene: ENSG00000273111 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LYPD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYPD4 | 147719 | 231266_at | 0.0061 | 0.9874 | |
| GSE26886 | LYPD4 | 147719 | 231266_at | -0.2700 | 0.0263 | |
| GSE45670 | LYPD4 | 147719 | 231266_at | -0.0268 | 0.8386 | |
| GSE53622 | LYPD4 | 147719 | 74489 | -0.7062 | 0.0000 | |
| GSE53624 | LYPD4 | 147719 | 74489 | -0.7536 | 0.0000 | |
| GSE63941 | LYPD4 | 147719 | 231266_at | 0.0443 | 0.8190 | |
| GSE77861 | LYPD4 | 147719 | 231266_at | -0.0545 | 0.6536 | |
| GSE97050 | LYPD4 | 147719 | A_23_P311780 | 0.2204 | 0.5391 | |
| TCGA | LYPD4 | 147719 | RNAseq | 2.4349 | 0.1790 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LYPD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LYPD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYPD4 | 147719 | 4 | 4 | 22 | |
| GSE20123 | LYPD4 | 147719 | 4 | 3 | 23 | |
| GSE43470 | LYPD4 | 147719 | 3 | 11 | 29 | |
| GSE46452 | LYPD4 | 147719 | 47 | 1 | 11 | |
| GSE47630 | LYPD4 | 147719 | 9 | 5 | 26 | |
| GSE54993 | LYPD4 | 147719 | 17 | 4 | 49 | |
| GSE54994 | LYPD4 | 147719 | 7 | 12 | 34 | |
| GSE60625 | LYPD4 | 147719 | 9 | 0 | 2 | |
| GSE74703 | LYPD4 | 147719 | 3 | 7 | 26 | |
| GSE74704 | LYPD4 | 147719 | 4 | 1 | 15 | |
| TCGA | LYPD4 | 147719 | 14 | 15 | 67 |
Total number of gains: 121; Total number of losses: 63; Total Number of normals: 304.
Somatic mutations of LYPD4:
Generating mutation plots.
Highly correlated genes for LYPD4:
Showing top 20/82 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYPD4 | SV2C | 0.709833 | 3 | 0 | 3 |
| LYPD4 | HPD | 0.708971 | 3 | 0 | 3 |
| LYPD4 | SEC14L3 | 0.704209 | 3 | 0 | 3 |
| LYPD4 | MMP17 | 0.696995 | 3 | 0 | 3 |
| LYPD4 | MYH14 | 0.668875 | 3 | 0 | 3 |
| LYPD4 | BCKDHA | 0.66548 | 3 | 0 | 3 |
| LYPD4 | TGM7 | 0.658256 | 4 | 0 | 3 |
| LYPD4 | CDC20B | 0.657095 | 3 | 0 | 3 |
| LYPD4 | ANKRD33 | 0.650748 | 3 | 0 | 3 |
| LYPD4 | C19orf73 | 0.650113 | 3 | 0 | 3 |
| LYPD4 | HRCT1 | 0.637807 | 3 | 0 | 3 |
| LYPD4 | MAMSTR | 0.636636 | 3 | 0 | 3 |
| LYPD4 | MEP1B | 0.634583 | 4 | 0 | 4 |
| LYPD4 | TNR | 0.633437 | 3 | 0 | 3 |
| LYPD4 | LINC00587 | 0.621115 | 5 | 0 | 4 |
| LYPD4 | LCN8 | 0.620277 | 3 | 0 | 3 |
| LYPD4 | VRTN | 0.618545 | 4 | 0 | 3 |
| LYPD4 | WNT9B | 0.618389 | 6 | 0 | 5 |
| LYPD4 | KLHL34 | 0.611751 | 4 | 0 | 4 |
| LYPD4 | AQP10 | 0.611235 | 4 | 0 | 3 |
For details and further investigation, click here
