| Full name: heat shock protein family A (Hsp70) member 12B | Alias Symbol: dJ1009E24.2 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 116835 | HGNC ID: HGNC:16193 | Ensembl Gene: ENSG00000132622 | OMIM ID: 610702 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of HSPA12B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSPA12B | 116835 | 229172_at | -0.1818 | 0.7286 | |
| GSE26886 | HSPA12B | 116835 | 229172_at | 0.1163 | 0.5874 | |
| GSE45670 | HSPA12B | 116835 | 229172_at | -0.4545 | 0.0158 | |
| GSE53622 | HSPA12B | 116835 | 97276 | -0.7600 | 0.0000 | |
| GSE53624 | HSPA12B | 116835 | 97276 | -0.4570 | 0.0000 | |
| GSE63941 | HSPA12B | 116835 | 229172_at | -0.1155 | 0.4813 | |
| GSE77861 | HSPA12B | 116835 | 229172_at | -0.0224 | 0.8557 | |
| GSE97050 | HSPA12B | 116835 | A_23_P91334 | -0.3060 | 0.3603 | |
| SRP064894 | HSPA12B | 116835 | RNAseq | 0.9691 | 0.0211 | |
| SRP133303 | HSPA12B | 116835 | RNAseq | -0.3834 | 0.1949 | |
| SRP159526 | HSPA12B | 116835 | RNAseq | 0.3054 | 0.4919 | |
| SRP193095 | HSPA12B | 116835 | RNAseq | 0.8445 | 0.0001 | |
| SRP219564 | HSPA12B | 116835 | RNAseq | 0.2226 | 0.7032 | |
| TCGA | HSPA12B | 116835 | RNAseq | -0.3513 | 0.0122 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HSPA12B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSPA12B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSPA12B | 116835 | 12 | 3 | 15 | |
| GSE20123 | HSPA12B | 116835 | 13 | 3 | 14 | |
| GSE43470 | HSPA12B | 116835 | 10 | 1 | 32 | |
| GSE46452 | HSPA12B | 116835 | 26 | 1 | 32 | |
| GSE47630 | HSPA12B | 116835 | 18 | 4 | 18 | |
| GSE54993 | HSPA12B | 116835 | 2 | 14 | 54 | |
| GSE54994 | HSPA12B | 116835 | 24 | 2 | 27 | |
| GSE60625 | HSPA12B | 116835 | 0 | 0 | 11 | |
| GSE74703 | HSPA12B | 116835 | 9 | 1 | 26 | |
| GSE74704 | HSPA12B | 116835 | 8 | 1 | 11 | |
| TCGA | HSPA12B | 116835 | 39 | 11 | 46 |
Total number of gains: 161; Total number of losses: 41; Total Number of normals: 286.
Somatic mutations of HSPA12B:
Generating mutation plots.
Highly correlated genes for HSPA12B:
Showing top 20/107 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSPA12B | HTR3A | 0.792956 | 3 | 0 | 3 |
| HSPA12B | OR10G8 | 0.761645 | 3 | 0 | 3 |
| HSPA12B | PHYHIP | 0.720184 | 3 | 0 | 3 |
| HSPA12B | OR2Z1 | 0.711157 | 3 | 0 | 3 |
| HSPA12B | TM6SF1 | 0.704902 | 3 | 0 | 3 |
| HSPA12B | FGF17 | 0.704752 | 3 | 0 | 3 |
| HSPA12B | GTF2IRD2B | 0.704344 | 3 | 0 | 3 |
| HSPA12B | SIGLEC8 | 0.692913 | 3 | 0 | 3 |
| HSPA12B | FAM171A2 | 0.686974 | 3 | 0 | 3 |
| HSPA12B | UPB1 | 0.683486 | 3 | 0 | 3 |
| HSPA12B | GPR146 | 0.678753 | 3 | 0 | 3 |
| HSPA12B | ZMYND10 | 0.678506 | 3 | 0 | 3 |
| HSPA12B | FGD5 | 0.673245 | 4 | 0 | 3 |
| HSPA12B | GPR88 | 0.668058 | 4 | 0 | 4 |
| HSPA12B | TCEAL7 | 0.667195 | 5 | 0 | 4 |
| HSPA12B | CABP1 | 0.666127 | 3 | 0 | 3 |
| HSPA12B | TXLNB | 0.653747 | 4 | 0 | 3 |
| HSPA12B | CLCN1 | 0.652436 | 3 | 0 | 3 |
| HSPA12B | RASGRF2 | 0.65101 | 4 | 0 | 3 |
| HSPA12B | KLHL10 | 0.65021 | 4 | 0 | 3 |
For details and further investigation, click here
