| Full name: ubiquitin interaction motif containing 1 | Alias Symbol: RAP80 | ||
| Type: protein-coding gene | Cytoband: 5q35.2 | ||
| Entrez ID: 51720 | HGNC ID: HGNC:30298 | Ensembl Gene: ENSG00000087206 | OMIM ID: 609433 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UIMC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UIMC1 | 51720 | 220746_s_at | -0.3463 | 0.3522 | |
| GSE20347 | UIMC1 | 51720 | 220746_s_at | 0.0920 | 0.5219 | |
| GSE23400 | UIMC1 | 51720 | 220746_s_at | -0.0281 | 0.7039 | |
| GSE26886 | UIMC1 | 51720 | 220746_s_at | 0.2524 | 0.2773 | |
| GSE29001 | UIMC1 | 51720 | 220746_s_at | -0.1883 | 0.5251 | |
| GSE38129 | UIMC1 | 51720 | 220746_s_at | -0.0403 | 0.7667 | |
| GSE45670 | UIMC1 | 51720 | 220746_s_at | -0.3209 | 0.0770 | |
| GSE53622 | UIMC1 | 51720 | 15479 | -0.4066 | 0.0000 | |
| GSE53624 | UIMC1 | 51720 | 15479 | -0.3514 | 0.0000 | |
| GSE63941 | UIMC1 | 51720 | 220746_s_at | -0.2062 | 0.6245 | |
| GSE77861 | UIMC1 | 51720 | 220746_s_at | -0.0027 | 0.9963 | |
| GSE97050 | UIMC1 | 51720 | A_23_P317691 | -0.2738 | 0.2713 | |
| SRP007169 | UIMC1 | 51720 | RNAseq | -0.1383 | 0.7464 | |
| SRP008496 | UIMC1 | 51720 | RNAseq | -0.2229 | 0.4156 | |
| SRP064894 | UIMC1 | 51720 | RNAseq | 0.1494 | 0.2033 | |
| SRP133303 | UIMC1 | 51720 | RNAseq | 0.1418 | 0.2265 | |
| SRP159526 | UIMC1 | 51720 | RNAseq | -0.0132 | 0.9659 | |
| SRP193095 | UIMC1 | 51720 | RNAseq | 0.1415 | 0.1626 | |
| SRP219564 | UIMC1 | 51720 | RNAseq | 0.1291 | 0.6783 | |
| TCGA | UIMC1 | 51720 | RNAseq | 0.0135 | 0.8120 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UIMC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UIMC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UIMC1 | 51720 | 2 | 13 | 15 | |
| GSE20123 | UIMC1 | 51720 | 2 | 13 | 15 | |
| GSE43470 | UIMC1 | 51720 | 1 | 11 | 31 | |
| GSE46452 | UIMC1 | 51720 | 0 | 27 | 32 | |
| GSE47630 | UIMC1 | 51720 | 0 | 20 | 20 | |
| GSE54993 | UIMC1 | 51720 | 10 | 2 | 58 | |
| GSE54994 | UIMC1 | 51720 | 2 | 17 | 34 | |
| GSE60625 | UIMC1 | 51720 | 1 | 0 | 10 | |
| GSE74703 | UIMC1 | 51720 | 1 | 7 | 28 | |
| GSE74704 | UIMC1 | 51720 | 1 | 6 | 13 | |
| TCGA | UIMC1 | 51720 | 7 | 35 | 54 |
Total number of gains: 27; Total number of losses: 151; Total Number of normals: 310.
Somatic mutations of UIMC1:
Generating mutation plots.
Highly correlated genes for UIMC1:
Showing top 20/223 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UIMC1 | KPNA3 | 0.759216 | 3 | 0 | 3 |
| UIMC1 | ZMAT1 | 0.754669 | 3 | 0 | 3 |
| UIMC1 | ZNF449 | 0.743637 | 3 | 0 | 3 |
| UIMC1 | TOMM40L | 0.737193 | 3 | 0 | 3 |
| UIMC1 | KLHL3 | 0.705321 | 3 | 0 | 3 |
| UIMC1 | GALNT11 | 0.692567 | 3 | 0 | 3 |
| UIMC1 | CCDC97 | 0.687942 | 3 | 0 | 3 |
| UIMC1 | CITED2 | 0.687689 | 3 | 0 | 3 |
| UIMC1 | C20orf194 | 0.686376 | 3 | 0 | 3 |
| UIMC1 | EPC2 | 0.682027 | 4 | 0 | 3 |
| UIMC1 | SCAPER | 0.679677 | 3 | 0 | 3 |
| UIMC1 | RSF1 | 0.677817 | 3 | 0 | 3 |
| UIMC1 | EFCAB7 | 0.673655 | 3 | 0 | 3 |
| UIMC1 | KIAA2026 | 0.663006 | 3 | 0 | 3 |
| UIMC1 | INPP5E | 0.662221 | 3 | 0 | 3 |
| UIMC1 | MRPL9 | 0.661872 | 3 | 0 | 3 |
| UIMC1 | CLYBL | 0.660875 | 4 | 0 | 3 |
| UIMC1 | FEM1C | 0.659088 | 4 | 0 | 3 |
| UIMC1 | CACNA2D2 | 0.659073 | 4 | 0 | 3 |
| UIMC1 | DNAJC27 | 0.658119 | 4 | 0 | 3 |
For details and further investigation, click here
