| Full name: citrate lyase beta like | Alias Symbol: CLB | ||
| Type: protein-coding gene | Cytoband: 13q32.3 | ||
| Entrez ID: 171425 | HGNC ID: HGNC:18355 | Ensembl Gene: ENSG00000125246 | OMIM ID: 609686 |
| Drug and gene relationship at DGIdb | |||
Expression of CLYBL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLYBL | 171425 | 238440_at | -1.1705 | 0.1168 | |
| GSE26886 | CLYBL | 171425 | 238440_at | -0.7524 | 0.0587 | |
| GSE45670 | CLYBL | 171425 | 238440_at | -1.0890 | 0.0026 | |
| GSE53622 | CLYBL | 171425 | 138385 | -1.1680 | 0.0000 | |
| GSE53624 | CLYBL | 171425 | 138385 | -1.5166 | 0.0000 | |
| GSE63941 | CLYBL | 171425 | 238440_at | 1.9971 | 0.0357 | |
| GSE77861 | CLYBL | 171425 | 238440_at | -0.5937 | 0.1985 | |
| GSE97050 | CLYBL | 171425 | A_23_P376591 | -0.8398 | 0.1287 | |
| SRP007169 | CLYBL | 171425 | RNAseq | -1.0639 | 0.0507 | |
| SRP064894 | CLYBL | 171425 | RNAseq | -0.7361 | 0.0015 | |
| SRP133303 | CLYBL | 171425 | RNAseq | -1.2601 | 0.0002 | |
| SRP159526 | CLYBL | 171425 | RNAseq | -1.3920 | 0.0000 | |
| SRP193095 | CLYBL | 171425 | RNAseq | -1.1695 | 0.0000 | |
| SRP219564 | CLYBL | 171425 | RNAseq | -1.0172 | 0.0582 | |
| TCGA | CLYBL | 171425 | RNAseq | -0.5561 | 0.0021 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by CLYBL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLYBL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLYBL | 171425 | 3 | 9 | 18 | |
| GSE20123 | CLYBL | 171425 | 3 | 8 | 19 | |
| GSE43470 | CLYBL | 171425 | 4 | 12 | 27 | |
| GSE46452 | CLYBL | 171425 | 0 | 32 | 27 | |
| GSE47630 | CLYBL | 171425 | 3 | 26 | 11 | |
| GSE54993 | CLYBL | 171425 | 11 | 4 | 55 | |
| GSE54994 | CLYBL | 171425 | 6 | 10 | 37 | |
| GSE60625 | CLYBL | 171425 | 0 | 3 | 8 | |
| GSE74703 | CLYBL | 171425 | 3 | 10 | 23 | |
| GSE74704 | CLYBL | 171425 | 1 | 8 | 11 | |
| TCGA | CLYBL | 171425 | 16 | 35 | 45 |
Total number of gains: 50; Total number of losses: 157; Total Number of normals: 281.
Somatic mutations of CLYBL:
Generating mutation plots.
Highly correlated genes for CLYBL:
Showing top 20/718 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLYBL | FBXL3 | 0.775553 | 4 | 0 | 4 |
| CLYBL | KAT6B | 0.769743 | 5 | 0 | 5 |
| CLYBL | CYTH2 | 0.757737 | 3 | 0 | 3 |
| CLYBL | TSPAN31 | 0.747555 | 3 | 0 | 3 |
| CLYBL | CIRBP | 0.739752 | 5 | 0 | 5 |
| CLYBL | RNF148 | 0.738785 | 3 | 0 | 3 |
| CLYBL | SLC12A6 | 0.735412 | 3 | 0 | 3 |
| CLYBL | CRBN | 0.722458 | 5 | 0 | 4 |
| CLYBL | CA11 | 0.719343 | 3 | 0 | 3 |
| CLYBL | ALDH6A1 | 0.718797 | 6 | 0 | 6 |
| CLYBL | TDRD3 | 0.717727 | 7 | 0 | 7 |
| CLYBL | RALGPS1 | 0.717521 | 7 | 0 | 7 |
| CLYBL | XPC | 0.714526 | 4 | 0 | 4 |
| CLYBL | UGP2 | 0.714027 | 3 | 0 | 3 |
| CLYBL | AGGF1 | 0.71178 | 3 | 0 | 3 |
| CLYBL | RNF135 | 0.71165 | 3 | 0 | 3 |
| CLYBL | RBM8A | 0.7111 | 3 | 0 | 3 |
| CLYBL | OXR1 | 0.710965 | 6 | 0 | 6 |
| CLYBL | FDX1 | 0.705564 | 3 | 0 | 3 |
| CLYBL | CBLL1 | 0.704764 | 3 | 0 | 3 |
For details and further investigation, click here
