| Full name: fem-1 homolog C | Alias Symbol: KIAA1785|EUROIMAGE686608|EUROIMAGE783647|FEM1A | ||
| Type: protein-coding gene | Cytoband: 5q22.3 | ||
| Entrez ID: 56929 | HGNC ID: HGNC:16933 | Ensembl Gene: ENSG00000145780 | OMIM ID: 608767 |
| Drug and gene relationship at DGIdb | |||
Expression of FEM1C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FEM1C | 56929 | 213341_at | -0.8822 | 0.1921 | |
| GSE20347 | FEM1C | 56929 | 213341_at | -0.7460 | 0.0002 | |
| GSE23400 | FEM1C | 56929 | 213341_at | -0.5810 | 0.0000 | |
| GSE26886 | FEM1C | 56929 | 213341_at | -1.2207 | 0.0003 | |
| GSE29001 | FEM1C | 56929 | 213341_at | -0.4761 | 0.1400 | |
| GSE38129 | FEM1C | 56929 | 213341_at | -0.7555 | 0.0000 | |
| GSE45670 | FEM1C | 56929 | 213341_at | -0.3694 | 0.1066 | |
| GSE53622 | FEM1C | 56929 | 65005 | -0.6677 | 0.0000 | |
| GSE53624 | FEM1C | 56929 | 65005 | -0.4075 | 0.0000 | |
| GSE63941 | FEM1C | 56929 | 213341_at | 0.0456 | 0.9412 | |
| GSE77861 | FEM1C | 56929 | 213341_at | -0.3492 | 0.3765 | |
| GSE97050 | FEM1C | 56929 | A_33_P3383871 | -0.8834 | 0.1313 | |
| SRP007169 | FEM1C | 56929 | RNAseq | -1.3250 | 0.0013 | |
| SRP008496 | FEM1C | 56929 | RNAseq | -1.3053 | 0.0000 | |
| SRP064894 | FEM1C | 56929 | RNAseq | -0.7373 | 0.0048 | |
| SRP133303 | FEM1C | 56929 | RNAseq | 0.0647 | 0.6877 | |
| SRP159526 | FEM1C | 56929 | RNAseq | -0.9859 | 0.0008 | |
| SRP193095 | FEM1C | 56929 | RNAseq | -0.8804 | 0.0000 | |
| SRP219564 | FEM1C | 56929 | RNAseq | -0.7000 | 0.2124 | |
| TCGA | FEM1C | 56929 | RNAseq | -0.3104 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by FEM1C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FEM1C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FEM1C | 56929 | 1 | 13 | 16 | |
| GSE20123 | FEM1C | 56929 | 1 | 13 | 16 | |
| GSE43470 | FEM1C | 56929 | 3 | 8 | 32 | |
| GSE46452 | FEM1C | 56929 | 0 | 28 | 31 | |
| GSE47630 | FEM1C | 56929 | 0 | 21 | 19 | |
| GSE54993 | FEM1C | 56929 | 9 | 1 | 60 | |
| GSE54994 | FEM1C | 56929 | 1 | 15 | 37 | |
| GSE60625 | FEM1C | 56929 | 0 | 0 | 11 | |
| GSE74703 | FEM1C | 56929 | 2 | 6 | 28 | |
| GSE74704 | FEM1C | 56929 | 1 | 7 | 12 | |
| TCGA | FEM1C | 56929 | 2 | 41 | 53 |
Total number of gains: 20; Total number of losses: 153; Total Number of normals: 315.
Somatic mutations of FEM1C:
Generating mutation plots.
Highly correlated genes for FEM1C:
Showing top 20/876 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FEM1C | MYO9A | 0.763034 | 3 | 0 | 3 |
| FEM1C | USP12 | 0.760926 | 3 | 0 | 3 |
| FEM1C | LRFN5 | 0.745513 | 3 | 0 | 3 |
| FEM1C | PIGP | 0.724258 | 4 | 0 | 4 |
| FEM1C | KDM3A | 0.723006 | 3 | 0 | 3 |
| FEM1C | PTGR1 | 0.716396 | 3 | 0 | 3 |
| FEM1C | JUN | 0.716368 | 4 | 0 | 3 |
| FEM1C | LSM11 | 0.716233 | 4 | 0 | 3 |
| FEM1C | EIF5 | 0.715798 | 3 | 0 | 3 |
| FEM1C | CCNDBP1 | 0.713648 | 3 | 0 | 3 |
| FEM1C | SPOP | 0.712473 | 4 | 0 | 4 |
| FEM1C | IGIP | 0.710138 | 4 | 0 | 3 |
| FEM1C | N4BP1 | 0.70802 | 3 | 0 | 3 |
| FEM1C | ASB5 | 0.705237 | 4 | 0 | 3 |
| FEM1C | RHOJ | 0.700127 | 3 | 0 | 3 |
| FEM1C | SNAP29 | 0.699448 | 5 | 0 | 4 |
| FEM1C | SS18 | 0.695615 | 3 | 0 | 3 |
| FEM1C | KCTD10 | 0.695548 | 3 | 0 | 3 |
| FEM1C | EXOC6B | 0.695506 | 4 | 0 | 3 |
| FEM1C | PPP1R11 | 0.694711 | 3 | 0 | 3 |
For details and further investigation, click here
