| Full name: inositol polyphosphate-5-phosphatase E | Alias Symbol: PPI5PIV|CORS1|pharbin | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 56623 | HGNC ID: HGNC:21474 | Ensembl Gene: ENSG00000148384 | OMIM ID: 613037 |
| Drug and gene relationship at DGIdb | |||
Expression of INPP5E:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INPP5E | 56623 | 204706_at | 0.0908 | 0.8727 | |
| GSE20347 | INPP5E | 56623 | 204706_at | 0.2708 | 0.1021 | |
| GSE23400 | INPP5E | 56623 | 204706_at | 0.2296 | 0.0000 | |
| GSE26886 | INPP5E | 56623 | 204706_at | 0.1110 | 0.6989 | |
| GSE29001 | INPP5E | 56623 | 204706_at | 0.4838 | 0.2220 | |
| GSE38129 | INPP5E | 56623 | 204706_at | 0.2116 | 0.0816 | |
| GSE45670 | INPP5E | 56623 | 204706_at | 0.0500 | 0.7918 | |
| GSE53622 | INPP5E | 56623 | 144540 | 0.3276 | 0.0002 | |
| GSE53624 | INPP5E | 56623 | 144540 | 0.5210 | 0.0000 | |
| GSE63941 | INPP5E | 56623 | 204706_at | 0.1244 | 0.7753 | |
| GSE77861 | INPP5E | 56623 | 204706_at | 0.2994 | 0.0279 | |
| GSE97050 | INPP5E | 56623 | A_24_P317835 | -0.0768 | 0.7426 | |
| SRP007169 | INPP5E | 56623 | RNAseq | 0.1517 | 0.7520 | |
| SRP008496 | INPP5E | 56623 | RNAseq | 0.0111 | 0.9743 | |
| SRP064894 | INPP5E | 56623 | RNAseq | 0.7112 | 0.0037 | |
| SRP133303 | INPP5E | 56623 | RNAseq | 0.3065 | 0.1080 | |
| SRP159526 | INPP5E | 56623 | RNAseq | 0.8024 | 0.0457 | |
| SRP193095 | INPP5E | 56623 | RNAseq | 0.4968 | 0.0001 | |
| SRP219564 | INPP5E | 56623 | RNAseq | 0.4577 | 0.3161 | |
| TCGA | INPP5E | 56623 | RNAseq | 0.1793 | 0.0042 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by INPP5E expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of INPP5E:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INPP5E | 56623 | 4 | 7 | 19 | |
| GSE20123 | INPP5E | 56623 | 4 | 7 | 19 | |
| GSE43470 | INPP5E | 56623 | 3 | 7 | 33 | |
| GSE46452 | INPP5E | 56623 | 6 | 13 | 40 | |
| GSE47630 | INPP5E | 56623 | 6 | 15 | 19 | |
| GSE54993 | INPP5E | 56623 | 3 | 3 | 64 | |
| GSE54994 | INPP5E | 56623 | 13 | 7 | 33 | |
| GSE60625 | INPP5E | 56623 | 0 | 0 | 11 | |
| GSE74703 | INPP5E | 56623 | 3 | 5 | 28 | |
| GSE74704 | INPP5E | 56623 | 2 | 5 | 13 | |
| TCGA | INPP5E | 56623 | 29 | 24 | 43 |
Total number of gains: 73; Total number of losses: 93; Total Number of normals: 322.
Somatic mutations of INPP5E:
Generating mutation plots.
Highly correlated genes for INPP5E:
Showing top 20/537 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INPP5E | STRADA | 0.823354 | 3 | 0 | 3 |
| INPP5E | NRL | 0.786569 | 3 | 0 | 3 |
| INPP5E | GLS | 0.783829 | 3 | 0 | 3 |
| INPP5E | TGFB1I1 | 0.782453 | 3 | 0 | 3 |
| INPP5E | PHKA1 | 0.774907 | 3 | 0 | 3 |
| INPP5E | ARF1 | 0.772674 | 3 | 0 | 3 |
| INPP5E | DHRSX | 0.768078 | 3 | 0 | 3 |
| INPP5E | FAM193B | 0.767781 | 3 | 0 | 3 |
| INPP5E | ZNF260 | 0.76662 | 3 | 0 | 3 |
| INPP5E | BCL9 | 0.754663 | 3 | 0 | 3 |
| INPP5E | NUCB1 | 0.751603 | 3 | 0 | 3 |
| INPP5E | MTMR11 | 0.751506 | 3 | 0 | 3 |
| INPP5E | LDB1 | 0.747619 | 3 | 0 | 3 |
| INPP5E | GSK3A | 0.743319 | 3 | 0 | 3 |
| INPP5E | USF2 | 0.738249 | 4 | 0 | 4 |
| INPP5E | CXXC1 | 0.737898 | 4 | 0 | 4 |
| INPP5E | NEK3 | 0.73739 | 4 | 0 | 4 |
| INPP5E | CACNA1B | 0.736302 | 3 | 0 | 3 |
| INPP5E | ZNF567 | 0.731483 | 3 | 0 | 3 |
| INPP5E | MFGE8 | 0.73006 | 4 | 0 | 3 |
For details and further investigation, click here
