| Full name: Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 | Alias Symbol: MRG1 | ||
| Type: protein-coding gene | Cytoband: 6q24.1 | ||
| Entrez ID: 10370 | HGNC ID: HGNC:1987 | Ensembl Gene: ENSG00000164442 | OMIM ID: 602937 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CITED2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CITED2 | 10370 | 209357_at | -2.1402 | 0.0445 | |
| GSE20347 | CITED2 | 10370 | 209357_at | -2.4639 | 0.0000 | |
| GSE23400 | CITED2 | 10370 | 209357_at | -1.4336 | 0.0000 | |
| GSE26886 | CITED2 | 10370 | 209357_at | -2.5500 | 0.0000 | |
| GSE29001 | CITED2 | 10370 | 209357_at | -2.0247 | 0.0000 | |
| GSE38129 | CITED2 | 10370 | 209357_at | -2.3822 | 0.0000 | |
| GSE45670 | CITED2 | 10370 | 209357_at | -1.0731 | 0.0054 | |
| GSE53622 | CITED2 | 10370 | 116989 | -1.2331 | 0.0000 | |
| GSE53624 | CITED2 | 10370 | 116989 | -1.2950 | 0.0000 | |
| GSE63941 | CITED2 | 10370 | 209357_at | -2.0607 | 0.0465 | |
| GSE77861 | CITED2 | 10370 | 209357_at | -1.7157 | 0.0023 | |
| GSE97050 | CITED2 | 10370 | A_33_P3213374 | -0.9369 | 0.1318 | |
| SRP007169 | CITED2 | 10370 | RNAseq | -4.6927 | 0.0000 | |
| SRP008496 | CITED2 | 10370 | RNAseq | -4.0748 | 0.0000 | |
| SRP064894 | CITED2 | 10370 | RNAseq | -1.3795 | 0.0000 | |
| SRP133303 | CITED2 | 10370 | RNAseq | -1.2029 | 0.0000 | |
| SRP159526 | CITED2 | 10370 | RNAseq | -1.4433 | 0.0076 | |
| SRP193095 | CITED2 | 10370 | RNAseq | -1.9226 | 0.0000 | |
| SRP219564 | CITED2 | 10370 | RNAseq | -1.2980 | 0.0719 | |
| TCGA | CITED2 | 10370 | RNAseq | -0.4240 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 17.
Survival by CITED2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CITED2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CITED2 | 10370 | 2 | 4 | 24 | |
| GSE20123 | CITED2 | 10370 | 2 | 3 | 25 | |
| GSE43470 | CITED2 | 10370 | 5 | 0 | 38 | |
| GSE46452 | CITED2 | 10370 | 3 | 10 | 46 | |
| GSE47630 | CITED2 | 10370 | 9 | 4 | 27 | |
| GSE54993 | CITED2 | 10370 | 3 | 2 | 65 | |
| GSE54994 | CITED2 | 10370 | 8 | 8 | 37 | |
| GSE60625 | CITED2 | 10370 | 0 | 1 | 10 | |
| GSE74703 | CITED2 | 10370 | 4 | 0 | 32 | |
| GSE74704 | CITED2 | 10370 | 0 | 1 | 19 | |
| TCGA | CITED2 | 10370 | 11 | 18 | 67 |
Total number of gains: 47; Total number of losses: 51; Total Number of normals: 390.
Somatic mutations of CITED2:
Generating mutation plots.
Highly correlated genes for CITED2:
Showing top 20/1433 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CITED2 | SPNS2 | 0.866141 | 3 | 0 | 3 |
| CITED2 | EIF4E3 | 0.800049 | 7 | 0 | 7 |
| CITED2 | PCBP1-AS1 | 0.796472 | 4 | 0 | 4 |
| CITED2 | ARHGAP10 | 0.784264 | 12 | 0 | 12 |
| CITED2 | RAP1A | 0.778535 | 11 | 0 | 11 |
| CITED2 | CYP21A2 | 0.774062 | 3 | 0 | 3 |
| CITED2 | ZNRF1 | 0.76994 | 3 | 0 | 3 |
| CITED2 | SHROOM3 | 0.76818 | 7 | 0 | 7 |
| CITED2 | CLEC3B | 0.763296 | 3 | 0 | 3 |
| CITED2 | SORT1 | 0.748716 | 11 | 0 | 11 |
| CITED2 | SECISBP2L | 0.746948 | 12 | 0 | 12 |
| CITED2 | CYP4V2 | 0.741565 | 3 | 0 | 3 |
| CITED2 | NFIA | 0.736378 | 7 | 0 | 7 |
| CITED2 | GPD1L | 0.733484 | 11 | 0 | 11 |
| CITED2 | MSRB3 | 0.733448 | 4 | 0 | 4 |
| CITED2 | PPP1R3C | 0.732209 | 12 | 0 | 11 |
| CITED2 | HSPB8 | 0.729847 | 13 | 0 | 12 |
| CITED2 | COBL | 0.727993 | 11 | 0 | 11 |
| CITED2 | VAT1 | 0.727774 | 10 | 0 | 10 |
| CITED2 | CAMK2N1 | 0.726558 | 12 | 0 | 12 |
For details and further investigation, click here
