| Full name: enhancer of polycomb homolog 2 | Alias Symbol: DKFZP566F2124 | ||
| Type: protein-coding gene | Cytoband: 2q23.1 | ||
| Entrez ID: 26122 | HGNC ID: HGNC:24543 | Ensembl Gene: ENSG00000135999 | OMIM ID: 611000 |
| Drug and gene relationship at DGIdb | |||
Expression of EPC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPC2 | 26122 | 225838_at | -0.1553 | 0.7075 | |
| GSE26886 | EPC2 | 26122 | 225838_at | 0.2997 | 0.2131 | |
| GSE45670 | EPC2 | 26122 | 225838_at | -0.1018 | 0.6145 | |
| GSE53622 | EPC2 | 26122 | 30094 | -0.0204 | 0.8209 | |
| GSE53624 | EPC2 | 26122 | 98349 | -0.0563 | 0.4462 | |
| GSE63941 | EPC2 | 26122 | 225838_at | -0.8769 | 0.0798 | |
| GSE77861 | EPC2 | 26122 | 225838_at | 0.0532 | 0.7419 | |
| GSE97050 | EPC2 | 26122 | A_23_P359738 | -0.2839 | 0.2579 | |
| SRP007169 | EPC2 | 26122 | RNAseq | 0.1622 | 0.6506 | |
| SRP008496 | EPC2 | 26122 | RNAseq | 0.2726 | 0.2343 | |
| SRP064894 | EPC2 | 26122 | RNAseq | 0.0760 | 0.7700 | |
| SRP133303 | EPC2 | 26122 | RNAseq | 0.1322 | 0.1677 | |
| SRP159526 | EPC2 | 26122 | RNAseq | 0.0034 | 0.9895 | |
| SRP193095 | EPC2 | 26122 | RNAseq | -0.0600 | 0.5343 | |
| SRP219564 | EPC2 | 26122 | RNAseq | -0.1160 | 0.7422 | |
| TCGA | EPC2 | 26122 | RNAseq | -0.0530 | 0.3211 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EPC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EPC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPC2 | 26122 | 3 | 3 | 24 | |
| GSE20123 | EPC2 | 26122 | 3 | 3 | 24 | |
| GSE43470 | EPC2 | 26122 | 3 | 1 | 39 | |
| GSE46452 | EPC2 | 26122 | 1 | 4 | 54 | |
| GSE47630 | EPC2 | 26122 | 5 | 3 | 32 | |
| GSE54993 | EPC2 | 26122 | 0 | 5 | 65 | |
| GSE54994 | EPC2 | 26122 | 11 | 2 | 40 | |
| GSE60625 | EPC2 | 26122 | 0 | 3 | 8 | |
| GSE74703 | EPC2 | 26122 | 2 | 1 | 33 | |
| GSE74704 | EPC2 | 26122 | 3 | 1 | 16 | |
| TCGA | EPC2 | 26122 | 22 | 9 | 65 |
Total number of gains: 53; Total number of losses: 35; Total Number of normals: 400.
Somatic mutations of EPC2:
Generating mutation plots.
Highly correlated genes for EPC2:
Showing top 20/285 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPC2 | CAMK1 | 0.796393 | 3 | 0 | 3 |
| EPC2 | SAT2 | 0.791808 | 3 | 0 | 3 |
| EPC2 | ZMAT1 | 0.768274 | 3 | 0 | 3 |
| EPC2 | FAM120AOS | 0.747516 | 3 | 0 | 3 |
| EPC2 | FAN1 | 0.747433 | 3 | 0 | 3 |
| EPC2 | MAU2 | 0.723262 | 3 | 0 | 3 |
| EPC2 | UHRF1BP1L | 0.71928 | 3 | 0 | 3 |
| EPC2 | AEBP2 | 0.719037 | 3 | 0 | 3 |
| EPC2 | KPNA3 | 0.717507 | 3 | 0 | 3 |
| EPC2 | ZNF548 | 0.716649 | 3 | 0 | 3 |
| EPC2 | NPHP3 | 0.715046 | 3 | 0 | 3 |
| EPC2 | UBE3A | 0.71128 | 3 | 0 | 3 |
| EPC2 | ANKRD40 | 0.705889 | 4 | 0 | 3 |
| EPC2 | KIAA0753 | 0.705682 | 3 | 0 | 3 |
| EPC2 | RASSF3 | 0.70548 | 3 | 0 | 3 |
| EPC2 | VEZT | 0.703856 | 3 | 0 | 3 |
| EPC2 | BCL6 | 0.701805 | 3 | 0 | 3 |
| EPC2 | CDC26 | 0.698457 | 4 | 0 | 3 |
| EPC2 | DDX42 | 0.694389 | 3 | 0 | 3 |
| EPC2 | KLHL15 | 0.694174 | 4 | 0 | 3 |
For details and further investigation, click here
