XIRP2

 

Full name: xin actin binding repeat containing 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 2q24.3
Entrez ID: 129446 HGNC ID: HGNC:14303 Ensembl Gene: ENSG00000163092 OMIM ID: 609778
Drug and gene relationship at DGIdb

 

Expression of XIRP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 XIRP2 129446 228794_at 0.0220 0.9537
GSE26886 XIRP2 129446 228794_at 0.1975 0.1168
GSE45670 XIRP2 129446 228794_at 0.1137 0.3012
GSE53622 XIRP2 129446 90454 -0.0436 0.6900
GSE53624 XIRP2 129446 90454 0.0093 0.9236
GSE63941 XIRP2 129446 228794_at -0.0607 0.7092
GSE77861 XIRP2 129446 228794_at -0.0431 0.6332
GSE97050 XIRP2 129446 A_23_P108743 -2.2072 0.1061
TCGA XIRP2 129446 RNAseq 2.6522 0.0481

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by XIRP2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of XIRP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 XIRP2 129446 6 0 24
GSE20123 XIRP2 129446 5 0 25
GSE43470 XIRP2 129446 5 1 37
GSE46452 XIRP2 129446 1 4 54
GSE47630 XIRP2 129446 5 3 32
GSE54993 XIRP2 129446 0 5 65
GSE54994 XIRP2 129446 11 2 40
GSE60625 XIRP2 129446 0 3 8
GSE74703 XIRP2 129446 4 1 31
GSE74704 XIRP2 129446 2 0 18
TCGA XIRP2 129446 24 9 63

Total number of gains: 63; Total number of losses: 28; Total Number of normals: 397.  

 

Somatic mutations of XIRP2:

 

Generating mutation plots.

 

Highly correlated genes for XIRP2:

 

Showing all 9 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
XIRP2BTBD170.624752303
XIRP2SLC25A60.596035303
XIRP2DOK10.582182303
XIRP2GRIK1-AS10.578774303
XIRP2HMX20.555451303
XIRP2SFXN50.549039303
XIRP2C9orf500.54838403
XIRP2LDB30.54174303
XIRP2AKAP50.538586303

For details and further investigation, click here