| Full name: sideroflexin 5 | Alias Symbol: BBG-TCC|SLC56A5 | ||
| Type: protein-coding gene | Cytoband: 2p13.2 | ||
| Entrez ID: 94097 | HGNC ID: HGNC:16073 | Ensembl Gene: ENSG00000144040 | OMIM ID: 615572 |
| Drug and gene relationship at DGIdb | |||
Expression of SFXN5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFXN5 | 94097 | 226373_at | 0.4548 | 0.3569 | |
| GSE26886 | SFXN5 | 94097 | 226373_at | 0.4786 | 0.0219 | |
| GSE45670 | SFXN5 | 94097 | 226373_at | 0.2987 | 0.0005 | |
| GSE53622 | SFXN5 | 94097 | 48246 | -0.3645 | 0.0000 | |
| GSE53624 | SFXN5 | 94097 | 48246 | -0.3358 | 0.0000 | |
| GSE63941 | SFXN5 | 94097 | 226373_at | -0.2742 | 0.2992 | |
| GSE77861 | SFXN5 | 94097 | 226373_at | -0.0410 | 0.7480 | |
| GSE97050 | SFXN5 | 94097 | A_33_P3292896 | -0.5372 | 0.2336 | |
| SRP007169 | SFXN5 | 94097 | RNAseq | 0.9800 | 0.0878 | |
| SRP008496 | SFXN5 | 94097 | RNAseq | 0.9093 | 0.0355 | |
| SRP064894 | SFXN5 | 94097 | RNAseq | 1.2435 | 0.0000 | |
| SRP133303 | SFXN5 | 94097 | RNAseq | 0.8509 | 0.0003 | |
| SRP159526 | SFXN5 | 94097 | RNAseq | 0.9496 | 0.0044 | |
| SRP193095 | SFXN5 | 94097 | RNAseq | 0.5994 | 0.0007 | |
| SRP219564 | SFXN5 | 94097 | RNAseq | 0.8001 | 0.0474 | |
| TCGA | SFXN5 | 94097 | RNAseq | -0.1022 | 0.1524 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SFXN5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFXN5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFXN5 | 94097 | 11 | 1 | 18 | |
| GSE20123 | SFXN5 | 94097 | 11 | 1 | 18 | |
| GSE43470 | SFXN5 | 94097 | 3 | 0 | 40 | |
| GSE46452 | SFXN5 | 94097 | 2 | 3 | 54 | |
| GSE47630 | SFXN5 | 94097 | 7 | 0 | 33 | |
| GSE54993 | SFXN5 | 94097 | 0 | 6 | 64 | |
| GSE54994 | SFXN5 | 94097 | 11 | 0 | 42 | |
| GSE60625 | SFXN5 | 94097 | 0 | 3 | 8 | |
| GSE74703 | SFXN5 | 94097 | 3 | 0 | 33 | |
| GSE74704 | SFXN5 | 94097 | 9 | 0 | 11 | |
| TCGA | SFXN5 | 94097 | 38 | 2 | 56 |
Total number of gains: 95; Total number of losses: 16; Total Number of normals: 377.
Somatic mutations of SFXN5:
Generating mutation plots.
Highly correlated genes for SFXN5:
Showing top 20/78 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFXN5 | REPS2 | 0.757055 | 3 | 0 | 3 |
| SFXN5 | ASB16 | 0.660916 | 3 | 0 | 3 |
| SFXN5 | ARC | 0.646198 | 3 | 0 | 3 |
| SFXN5 | GM2A | 0.645187 | 3 | 0 | 3 |
| SFXN5 | APOL2 | 0.645028 | 3 | 0 | 3 |
| SFXN5 | CCDC78 | 0.641207 | 5 | 0 | 4 |
| SFXN5 | ARHGAP33 | 0.635257 | 4 | 0 | 4 |
| SFXN5 | DST | 0.634491 | 3 | 0 | 3 |
| SFXN5 | MOG | 0.626068 | 4 | 0 | 4 |
| SFXN5 | VMAC | 0.620377 | 3 | 0 | 3 |
| SFXN5 | SP110 | 0.619442 | 3 | 0 | 3 |
| SFXN5 | TMEM174 | 0.614958 | 3 | 0 | 3 |
| SFXN5 | KLC2 | 0.61345 | 3 | 0 | 3 |
| SFXN5 | C8orf58 | 0.609594 | 4 | 0 | 3 |
| SFXN5 | GLP2R | 0.603332 | 5 | 0 | 3 |
| SFXN5 | RBFOX1 | 0.602465 | 3 | 0 | 3 |
| SFXN5 | CLDN19 | 0.601885 | 4 | 0 | 3 |
| SFXN5 | EDA | 0.60033 | 4 | 0 | 4 |
| SFXN5 | EPN1 | 0.597504 | 3 | 0 | 3 |
| SFXN5 | SLC2A4RG | 0.597399 | 4 | 0 | 3 |
For details and further investigation, click here
