| Full name: solute carrier family 25 member 6 | Alias Symbol: ANT3Y|MGC17525 | ||
| Type: protein-coding gene | Cytoband: Xp22.32 and Yp11.3 | ||
| Entrez ID: 293 | HGNC ID: HGNC:10992 | Ensembl Gene: ENSG00000169100 | OMIM ID: 300151|403000 |
| Drug and gene relationship at DGIdb | |||
SLC25A6 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04020 | Calcium signaling pathway | |
| hsa04022 | cGMP-PKG signaling pathway | |
| hsa05012 | Parkinson's disease |
Expression of SLC25A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC25A6 | 293 | 212085_at | -0.1733 | 0.7221 | |
| GSE20347 | SLC25A6 | 293 | 212085_at | -0.3450 | 0.2270 | |
| GSE23400 | SLC25A6 | 293 | 212826_s_at | -0.2110 | 0.0433 | |
| GSE26886 | SLC25A6 | 293 | 212826_s_at | 0.2944 | 0.1311 | |
| GSE29001 | SLC25A6 | 293 | 212826_s_at | -0.4932 | 0.1580 | |
| GSE38129 | SLC25A6 | 293 | 212085_at | -0.3488 | 0.0590 | |
| GSE45670 | SLC25A6 | 293 | 212085_at | -0.4765 | 0.0168 | |
| GSE63941 | SLC25A6 | 293 | 212085_at | 0.7171 | 0.2595 | |
| GSE77861 | SLC25A6 | 293 | 212085_at | 0.3834 | 0.4643 | |
| GSE97050 | SLC25A6 | 293 | A_33_P3589217 | -0.2607 | 0.5112 | |
| SRP007169 | SLC25A6 | 293 | RNAseq | -1.2399 | 0.0032 | |
| SRP008496 | SLC25A6 | 293 | RNAseq | -1.2771 | 0.0000 | |
| SRP064894 | SLC25A6 | 293 | RNAseq | -0.1860 | 0.5785 | |
| SRP133303 | SLC25A6 | 293 | RNAseq | -0.2967 | 0.0729 | |
| SRP159526 | SLC25A6 | 293 | RNAseq | -0.3534 | 0.1678 | |
| SRP193095 | SLC25A6 | 293 | RNAseq | -0.7851 | 0.0000 | |
| SRP219564 | SLC25A6 | 293 | RNAseq | -0.1341 | 0.7252 | |
| TCGA | SLC25A6 | 293 | RNAseq | -0.1678 | 0.0048 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SLC25A6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SLC25A6:
No record found for this gene.
Somatic mutations of SLC25A6:
Generating mutation plots.
Highly correlated genes for SLC25A6:
Showing top 20/172 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC25A6 | PARM1 | 0.716975 | 3 | 0 | 3 |
| SLC25A6 | CHRDL1 | 0.692394 | 3 | 0 | 3 |
| SLC25A6 | PPM1M | 0.687729 | 3 | 0 | 3 |
| SLC25A6 | PNCK | 0.681722 | 3 | 0 | 3 |
| SLC25A6 | SETMAR | 0.678501 | 3 | 0 | 3 |
| SLC25A6 | GTPBP6 | 0.678154 | 11 | 0 | 10 |
| SLC25A6 | SMARCD2 | 0.674637 | 3 | 0 | 3 |
| SLC25A6 | NFIC | 0.67199 | 3 | 0 | 3 |
| SLC25A6 | RBM6 | 0.66702 | 4 | 0 | 3 |
| SLC25A6 | BTC | 0.665149 | 3 | 0 | 3 |
| SLC25A6 | CTSO | 0.663707 | 3 | 0 | 3 |
| SLC25A6 | TMEM143 | 0.654646 | 3 | 0 | 3 |
| SLC25A6 | USP20 | 0.650508 | 3 | 0 | 3 |
| SLC25A6 | TAB1 | 0.649716 | 3 | 0 | 3 |
| SLC25A6 | RALGPS1 | 0.643256 | 3 | 0 | 3 |
| SLC25A6 | DPP8 | 0.637744 | 3 | 0 | 3 |
| SLC25A6 | CEP68 | 0.633531 | 3 | 0 | 3 |
| SLC25A6 | RPS6KA2 | 0.631258 | 3 | 0 | 3 |
| SLC25A6 | BTG1 | 0.629919 | 4 | 0 | 3 |
| SLC25A6 | DNAJC11 | 0.624821 | 3 | 0 | 3 |
For details and further investigation, click here
