| Full name: zinc finger protein 280A | Alias Symbol: 3'OY11.1|ZNF636 | ||
| Type: protein-coding gene | Cytoband: 22q11.22 | ||
| Entrez ID: 129025 | HGNC ID: HGNC:18597 | Ensembl Gene: ENSG00000169548 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF280A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF280A | 129025 | 216034_at | -0.1834 | 0.5013 | |
| GSE20347 | ZNF280A | 129025 | 216034_at | -0.1737 | 0.0179 | |
| GSE23400 | ZNF280A | 129025 | 216034_at | -0.2427 | 0.0000 | |
| GSE26886 | ZNF280A | 129025 | 216034_at | -0.1879 | 0.1252 | |
| GSE29001 | ZNF280A | 129025 | 216034_at | -0.2028 | 0.1483 | |
| GSE38129 | ZNF280A | 129025 | 216034_at | -0.1460 | 0.0954 | |
| GSE45670 | ZNF280A | 129025 | 216034_at | -0.0447 | 0.7959 | |
| GSE63941 | ZNF280A | 129025 | 216034_at | 0.3694 | 0.3279 | |
| GSE77861 | ZNF280A | 129025 | 216034_at | -0.4177 | 0.0056 | |
| GSE97050 | ZNF280A | 129025 | A_23_P154972 | -0.2370 | 0.3571 | |
| TCGA | ZNF280A | 129025 | RNAseq | 4.5797 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNF280A expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZNF280A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF280A | 129025 | 5 | 7 | 18 | |
| GSE20123 | ZNF280A | 129025 | 5 | 6 | 19 | |
| GSE43470 | ZNF280A | 129025 | 3 | 6 | 34 | |
| GSE46452 | ZNF280A | 129025 | 32 | 1 | 26 | |
| GSE47630 | ZNF280A | 129025 | 8 | 5 | 27 | |
| GSE54993 | ZNF280A | 129025 | 3 | 6 | 61 | |
| GSE54994 | ZNF280A | 129025 | 11 | 7 | 35 | |
| GSE60625 | ZNF280A | 129025 | 5 | 0 | 6 | |
| GSE74703 | ZNF280A | 129025 | 3 | 5 | 28 | |
| GSE74704 | ZNF280A | 129025 | 2 | 3 | 15 | |
| TCGA | ZNF280A | 129025 | 27 | 16 | 53 |
Total number of gains: 104; Total number of losses: 62; Total Number of normals: 322.
Somatic mutations of ZNF280A:
Generating mutation plots.
Highly correlated genes for ZNF280A:
Showing top 20/722 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF280A | WNK2 | 0.730978 | 3 | 0 | 3 |
| ZNF280A | CCDC36 | 0.726664 | 4 | 0 | 4 |
| ZNF280A | C10orf67 | 0.719528 | 3 | 0 | 3 |
| ZNF280A | LCN8 | 0.707087 | 3 | 0 | 3 |
| ZNF280A | TSHB | 0.693759 | 6 | 0 | 6 |
| ZNF280A | ANKRD30A | 0.673557 | 3 | 0 | 3 |
| ZNF280A | SLC25A20 | 0.67122 | 3 | 0 | 3 |
| ZNF280A | C9orf131 | 0.671144 | 3 | 0 | 3 |
| ZNF280A | CD300LG | 0.670778 | 4 | 0 | 4 |
| ZNF280A | KNCN | 0.670585 | 3 | 0 | 3 |
| ZNF280A | GALR3 | 0.670308 | 6 | 0 | 6 |
| ZNF280A | LINC00632 | 0.66804 | 3 | 0 | 3 |
| ZNF280A | FOXN4 | 0.666095 | 3 | 0 | 3 |
| ZNF280A | SLC7A14 | 0.665267 | 3 | 0 | 3 |
| ZNF280A | ADCY1 | 0.665115 | 6 | 0 | 6 |
| ZNF280A | ABCC8 | 0.662859 | 8 | 0 | 7 |
| ZNF280A | SPERT | 0.662253 | 3 | 0 | 3 |
| ZNF280A | VASH2 | 0.660262 | 4 | 0 | 3 |
| ZNF280A | SMPX | 0.659524 | 3 | 0 | 3 |
| ZNF280A | LRTM2 | 0.658843 | 3 | 0 | 3 |
For details and further investigation, click here
