| Full name: solute carrier family 7 member 14 | Alias Symbol: KIAA1613|PPP1R142 | ||
| Type: protein-coding gene | Cytoband: 3q26.2 | ||
| Entrez ID: 57709 | HGNC ID: HGNC:29326 | Ensembl Gene: ENSG00000013293 | OMIM ID: 615720 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC7A14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC7A14 | 57709 | 232904_at | -0.0034 | 0.9895 | |
| GSE26886 | SLC7A14 | 57709 | 232904_at | -0.1420 | 0.1589 | |
| GSE45670 | SLC7A14 | 57709 | 232904_at | 0.0478 | 0.6231 | |
| GSE53622 | SLC7A14 | 57709 | 22802 | 0.0888 | 0.2525 | |
| GSE53624 | SLC7A14 | 57709 | 22802 | 0.1469 | 0.0773 | |
| GSE63941 | SLC7A14 | 57709 | 232904_at | 0.1565 | 0.3294 | |
| GSE77861 | SLC7A14 | 57709 | 1556641_at | -0.1599 | 0.0746 | |
| GSE97050 | SLC7A14 | A_19_P00805942 | -0.1221 | 0.5845 | ||
| SRP064894 | SLC7A14 | 57709 | RNAseq | -0.3862 | 0.1798 | |
| SRP133303 | SLC7A14 | 57709 | RNAseq | -0.1868 | 0.1255 | |
| SRP159526 | SLC7A14 | 57709 | RNAseq | -0.3114 | 0.2817 | |
| SRP193095 | SLC7A14 | 57709 | RNAseq | 0.0023 | 0.9856 | |
| SRP219564 | SLC7A14 | 57709 | RNAseq | -0.8807 | 0.0198 | |
| TCGA | SLC7A14 | 57709 | RNAseq | -2.9478 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC7A14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC7A14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC7A14 | 57709 | 22 | 0 | 8 | |
| GSE20123 | SLC7A14 | 57709 | 22 | 0 | 8 | |
| GSE43470 | SLC7A14 | 57709 | 24 | 0 | 19 | |
| GSE46452 | SLC7A14 | 57709 | 19 | 1 | 39 | |
| GSE47630 | SLC7A14 | 57709 | 27 | 2 | 11 | |
| GSE54993 | SLC7A14 | 57709 | 1 | 15 | 54 | |
| GSE54994 | SLC7A14 | 57709 | 41 | 0 | 12 | |
| GSE60625 | SLC7A14 | 57709 | 0 | 6 | 5 | |
| GSE74703 | SLC7A14 | 57709 | 20 | 0 | 16 | |
| GSE74704 | SLC7A14 | 57709 | 14 | 0 | 6 | |
| TCGA | SLC7A14 | 57709 | 80 | 0 | 16 |
Total number of gains: 270; Total number of losses: 24; Total Number of normals: 194.
Somatic mutations of SLC7A14:
Generating mutation plots.
Highly correlated genes for SLC7A14:
Showing top 20/68 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC7A14 | SCGN | 0.77585 | 3 | 0 | 3 |
| SLC7A14 | SLC25A18 | 0.764546 | 3 | 0 | 3 |
| SLC7A14 | OR2D3 | 0.746819 | 3 | 0 | 3 |
| SLC7A14 | CADPS | 0.729092 | 3 | 0 | 3 |
| SLC7A14 | C20orf173 | 0.725223 | 3 | 0 | 3 |
| SLC7A14 | OR2T1 | 0.721825 | 3 | 0 | 3 |
| SLC7A14 | SYPL2 | 0.712082 | 3 | 0 | 3 |
| SLC7A14 | CLEC1B | 0.696826 | 3 | 0 | 3 |
| SLC7A14 | G6PC | 0.684553 | 3 | 0 | 3 |
| SLC7A14 | KCNJ13 | 0.682499 | 3 | 0 | 3 |
| SLC7A14 | RASGRF2 | 0.682106 | 4 | 0 | 3 |
| SLC7A14 | FNDC9 | 0.674107 | 3 | 0 | 3 |
| SLC7A14 | FAM171A2 | 0.671791 | 3 | 0 | 3 |
| SLC7A14 | ZNF280A | 0.665267 | 3 | 0 | 3 |
| SLC7A14 | AQP4 | 0.6568 | 5 | 0 | 4 |
| SLC7A14 | TAS2R39 | 0.65221 | 5 | 0 | 4 |
| SLC7A14 | ANO7 | 0.651634 | 5 | 0 | 3 |
| SLC7A14 | CELF4 | 0.651171 | 4 | 0 | 3 |
| SLC7A14 | RALYL | 0.645422 | 5 | 0 | 4 |
| SLC7A14 | GRID2 | 0.642639 | 4 | 0 | 3 |
For details and further investigation, click here
